Predictors of switching antipsychotic medications in the treatment of schizophrenia

• Published in: BMC psychiatry Vol. 10; no. 1; p. 75
• Main Authors: Nyhuis, Allen W, Faries, Douglas E, Ascher-Svanum, Haya, Stauffer, Virginia L, Kinon, Bruce J
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.09.2010; BioMed Central; BMC
• Subjects: Ambulatory Care; Antipsychotic Agents - administration & dosage; Antipsychotic Agents - therapeutic use; Antipsychotic drugs; Care and treatment; Clinical medicine; Cost control; Drug Administration Schedule; Female; Follow-Up Studies; Health aspects; Humans; Male; Middle Aged; Multicenter Studies as Topic - statistics & numerical data; Patient outcomes; Probability; Proportional Hazards Models; Psychiatric Status Rating Scales - statistics & numerical data; Psychiatry; Psychotropic drugs; Randomized Controlled Trials as Topic - statistics & numerical data; Schizophrenia; Schizophrenia - diagnosis; Schizophrenia - drug therapy; Schizophrenic Psychology; Severity of Illness Index; Survival Analysis; Treatment Outcome; United States

To identify patient characteristics and early changes in patients' clinical status that best predict subsequent switching of antipsychotic agents in the long-term treatment of schizophrenia. This post-hoc analysis used data from a one-year randomized, open-label, multisite study of antipsychoti...