Evaluation of chloroquine therapy for vivax and falciparum malaria in southern Sumatra, western Indonesia

• Published in: Malaria journal Vol. 9; no. 1; p. 52
• Main Authors: Sutanto, Inge, Endawati, Dedeh, Ling, Liem Hui, Laihad, Ferdinand, Setiabudy, Rianto, Baird, J Kevin
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 12.02.2010; BioMed Central; BMC
• Subjects: Adolescent; Adult; Animals; Antimalarials - pharmacology; Antimalarials - therapeutic use; Archipelagoes; Artemisinin; Asexuality; Blood; Causes of; Child; Child, Preschool; Chloroquine; Chloroquine - blood; Chloroquine - pharmacology; Chloroquine - therapeutic use; Complications and side effects; Demographic aspects; Dosage and administration; Drug Resistance; Drug resistance in microorganisms; Drug therapy; Drugs; Enrollments; Erythrocytes; Failure; Failures; Female; Human diseases; Humans; Indonesia; Infant; Infections; Malaria; Malaria, Falciparum - drug therapy; Malaria, Vivax - drug therapy; Male; Metabolites; Middle Aged; Parasitemia - drug therapy; Parasites; Plasmodium falciparum; Plasmodium falciparum - drug effects; Plasmodium falciparum - isolation & purification; Plasmodium vivax; Plasmodium vivax - drug effects; Plasmodium vivax - isolation & purification; Recurrence; Studies; Treatment Failure; Urine; Vector-borne diseases; Young Adult; Indonesia; Sumatra

Chloroquine was used as first-line treatment for Plasmodium falciparum or Plasmodium vivax in Indonesia before the initial launch of artemisinin combination therapy in 2004. A study to evaluate efficacies of chloroquine against P. falciparum and P. vivax was undertaken at Lampung in southern Sumatra...