AllerTOP--a server for in silico prediction of allergens

• Published in: BMC bioinformatics Vol. 14 Suppl 6; no. Suppl 6; p. S4
• Main Authors: Dimitrov, Ivan, Flower, Darren R, Doytchinova, Irini
• Format: Journal Article
• Language: English
• Published: England BioMed Central 17.04.2013; BioMed Central Ltd
• Subjects: Algorithms; Allergens - chemistry; Allergens - immunology; Allergies; Amino Acid Sequence; Amino acids; Artificial Intelligence; Bayes Theorem; Bioinformatics; Computational Biology - methods; Computer Simulation; Databases, Protein; Food Hypersensitivity; Humans; Hypersensitivity - immunology; Proceedings; Proteins; Proteins - chemistry; Proteins - immunology; Studies; Toxins, Biological - chemistry; Toxins, Biological - immunology

Allergy is a form of hypersensitivity to normally innocuous substances, such as dust, pollen, foods or drugs. Allergens are small antigens that commonly provoke an IgE antibody response. There are two types of bioinformatics-based allergen prediction. The first approach follows FAO/WHO Codex aliment...