Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh
Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response...
Saved in:
| Published in | Environmental health Vol. 10; no. 1; p. 64 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
BioMed Central Ltd
08.07.2011
BioMed Central BMC |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh.
A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed.
Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics.
The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. |
|---|---|
| AbstractList | Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh.
A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed.
Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics.
The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. BACKGROUND: Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh. METHODS: A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed. RESULTS: Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics. CONCLUSIONS: The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh. A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed. Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics. The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh.BACKGROUNDChronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh.A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed.METHODSA total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed.Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics.RESULTSArsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics.The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases.CONCLUSIONSThe present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. Abstract Background Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a dose-response relationship with arsenic exposure has not yet been clearly documented. The aim of our study was to investigate the dose-response relationship between arsenic exposure and major serum enzyme marker activity associated with LFTs in the population living in arsenic-endemic areas in Bangladesh. Methods A total of 200 residents living in arsenic-endemic areas in Bangladesh were selected as study subjects. Arsenic concentrations in the drinking water, hair and nails were measured by Inductively Coupled Plasma Mass Spectroscopy (ICP-MS). The study subjects were stratified into quartile groups as follows, based on concentrations of arsenic in the drinking water, as well as in subjects' hair and nails: lowest, low, medium and high. The serum hepatic enzyme activities of alkaline phosphatase (ALP), aspartate transaminase (AST) and alanine transaminase (ALT) were then assayed. Results Arsenic concentrations in the subjects' hair and nails were positively correlated with arsenic levels in the drinking water. As regards the exposure-response relationship with arsenic in the drinking water, the respective activities of ALP, AST and ALT were found to be significantly increased in the high-exposure groups compared to the lowest-exposure groups before and after adjustments were made for different covariates. With internal exposure markers (arsenic in hair and nails), the ALP, AST and ALT activity profiles assumed a similar shape of dose-response relationship, with very few differences seen in the higher groups compared to the lowest group, most likely due to the temporalities of exposure metrics. Conclusions The present study demonstrated that arsenic concentrations in the drinking water were strongly correlated with arsenic concentrations in the subjects' hair and nails. Further, this study revealed a novel exposure- and dose- response relationship between arsenic exposure metrics and serum hepatic enzyme activity. Elevated serum hepatic enzyme activities in the higher exposure gradients provided new insights into arsenic-induced liver toxicity that might be helpful for the early prognosis of arsenic-induced liver diseases. |
| ArticleNumber | 64 |
| Audience | Academic |
| Author | Salam, Kazi Abdus Saud, Zahangir Alam Rahman, Matiar Mandal, Abul Hossain, Khaled Rahman, Mashiur Haque, Abedul Sultana, Papia Fajol, Abul Ali, Nurshad Miyataka, Hideki Islam, Khairul Akhand, Anwarul Azim Karim, Rezaul Himeno, Seiichiro Hossain, Ekhtear Hossain, Mostaque |
| AuthorAffiliation | 5 Department of Medicine, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh 6 Department of Genetic Engineering and Biotechnology, Dhaka University, Dhaka-1000, Bangladesh 8 Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan 7 System Biology Research Center, University of Skövde, P. O. Box 408, SE-541-28 Skövde, Sweden 2 Department of Applied Nutrition and Food Technology, Islamic University, Kushtia-7003, Bangladesh 4 Department of Statistics, Rajshahi University, Rajshahi-6205, Bangladesh 3 FIST, UMP, Gambang 26300, Pahang, Malaysia 1 Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205, Bangladesh |
| AuthorAffiliation_xml | – name: 5 Department of Medicine, Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh – name: 3 FIST, UMP, Gambang 26300, Pahang, Malaysia – name: 6 Department of Genetic Engineering and Biotechnology, Dhaka University, Dhaka-1000, Bangladesh – name: 8 Laboratory of Molecular Nutrition and Toxicology, Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Tokushima 770-8514, Japan – name: 7 System Biology Research Center, University of Skövde, P. O. Box 408, SE-541-28 Skövde, Sweden – name: 4 Department of Statistics, Rajshahi University, Rajshahi-6205, Bangladesh – name: 2 Department of Applied Nutrition and Food Technology, Islamic University, Kushtia-7003, Bangladesh – name: 1 Department of Biochemistry and Molecular Biology, Rajshahi University, Rajshahi-6205, Bangladesh |
| Author_xml | – sequence: 1 givenname: Khairul surname: Islam fullname: Islam, Khairul – sequence: 2 givenname: Abedul surname: Haque fullname: Haque, Abedul – sequence: 3 givenname: Rezaul surname: Karim fullname: Karim, Rezaul – sequence: 4 givenname: Abul surname: Fajol fullname: Fajol, Abul – sequence: 5 givenname: Ekhtear surname: Hossain fullname: Hossain, Ekhtear – sequence: 6 givenname: Kazi Abdus surname: Salam fullname: Salam, Kazi Abdus – sequence: 7 givenname: Nurshad surname: Ali fullname: Ali, Nurshad – sequence: 8 givenname: Zahangir Alam surname: Saud fullname: Saud, Zahangir Alam – sequence: 9 givenname: Matiar surname: Rahman fullname: Rahman, Matiar – sequence: 10 givenname: Mashiur surname: Rahman fullname: Rahman, Mashiur – sequence: 11 givenname: Papia surname: Sultana fullname: Sultana, Papia – sequence: 12 givenname: Mostaque surname: Hossain fullname: Hossain, Mostaque – sequence: 13 givenname: Anwarul Azim surname: Akhand fullname: Akhand, Anwarul Azim – sequence: 14 givenname: Abul surname: Mandal fullname: Mandal, Abul – sequence: 15 givenname: Hideki surname: Miyataka fullname: Miyataka, Hideki – sequence: 16 givenname: Seiichiro surname: Himeno fullname: Himeno, Seiichiro – sequence: 17 givenname: Khaled surname: Hossain fullname: Hossain, Khaled |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/21740555$$D View this record in MEDLINE/PubMed https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-5533$$DView record from Swedish Publication Index |
| BookMark | eNp1k0tv1DAUhSNURB-wZocssWCB0tp52AkLpGnLo1IlNoDYWTfJ9YyrxJ7ayZTyp_iLOEk76qBWkRLr-pwv9zonh9GesQaj6DWjx4wV_IRlgseUl79iRmOePYsOtpW9B-v96ND7K0qZKHj-ItpPmMhonucH0d9z6zF26NfWeCQOW-h1WK70mlTY3yAaAs6j0TXB32vrB4cETEP6FRKPbugImj-3HXqirCOt3qAjajD1SCE9-t4TbSa1No3e6GaA1s8oDBR7T_9AgNTOeh-okxla4vuhuR3tp2CWLTToVy-j5yoA8NXd8yj68fnT97Ov8eW3Lxdni8u44gnt40qF0RtWgoAwMgIXIlU1iKwqq6rIhBAUWJUp2jRQJXlWlimtcsWUSAEFh_Qoupi5jYUruXa6A3crLWg5FaxbSnC9rluUgAwxgUBJiixJMlAcKKNYAi9Ymo6s9zPL3-B6qHZo5_rnYqKttJd5nqZB_XFWB2mHTY2md9DumHZ3jF7Jpd3IlGW8ZEUAnM6AStsnALs7te3kGBU5RkUyKnkWIO_uunD2egifUXba19i2YNAOXhYFFUywfHzd21m5hHAY2igboPWolouEJyVNwy2ojh9RhavBTtch1EqH-o7hzcNj2LZ_H90gOJkFU2ocqq0kTDD-HI_MlP_nqHU_xT30otsnff8A2yMX7g |
| CitedBy_id | crossref_primary_10_1016_j_jtemb_2023_127128 crossref_primary_10_1016_j_pharep_2018_02_007 crossref_primary_10_1016_j_scitotenv_2012_02_079 crossref_primary_10_1210_jc_2013_2310 crossref_primary_10_1093_eep_dvac014 crossref_primary_10_1016_j_jtemb_2023_127366 crossref_primary_10_12980_APJTB_4_201414B44 crossref_primary_10_3109_0886022X_2015_1074462 crossref_primary_10_1007_s12011_021_03026_0 crossref_primary_10_1016_j_biopha_2021_112167 crossref_primary_10_1016_j_jtcme_2017_08_001 crossref_primary_10_1242_dmm_031575 crossref_primary_10_2903_j_efsa_2024_8488 crossref_primary_10_1002_aws2_1292 crossref_primary_10_1016_j_chemosphere_2019_125790 crossref_primary_10_1016_j_heliyon_2021_e06361 crossref_primary_10_5528_wjtm_v3_i2_96 crossref_primary_10_1007_s00420_013_0914_5 crossref_primary_10_1007_s12668_021_00920_8 crossref_primary_10_3390_ijerph16060977 crossref_primary_10_31083_j_fbl2711314 crossref_primary_10_1016_j_taap_2014_09_011 crossref_primary_10_1007_s11356_022_22724_3 crossref_primary_10_1016_j_envint_2020_105890 crossref_primary_10_1088_1361_6528_aa9fa2 crossref_primary_10_1016_j_reprotox_2016_10_001 crossref_primary_10_1186_s40360_021_00484_z crossref_primary_10_1039_c3fo60237k crossref_primary_10_2131_jts_44_83 crossref_primary_10_1186_1471_2458_13_74 crossref_primary_10_1007_s10695_025_01484_0 crossref_primary_10_1186_s12199_019_0781_0 crossref_primary_10_1186_s12940_015_0079_7 crossref_primary_10_3390_ijms232012213 crossref_primary_10_1021_acs_jpcc_4c02905 crossref_primary_10_1016_j_chemosphere_2014_08_003 crossref_primary_10_1016_j_ecoenv_2024_116283 crossref_primary_10_1038_s41598_021_85780_8 crossref_primary_10_1016_j_cscee_2021_100103 crossref_primary_10_1016_j_ecoenv_2025_118038 crossref_primary_10_1093_toxsci_kft130 crossref_primary_10_1186_s40360_016_0091_8 crossref_primary_10_3390_ijerph13010062 crossref_primary_10_1016_j_ecoenv_2020_111719 crossref_primary_10_1016_j_envres_2017_02_002 crossref_primary_10_1016_j_scitotenv_2019_03_029 crossref_primary_10_1016_j_taap_2022_116166 crossref_primary_10_3390_ijms25126662 crossref_primary_10_1016_j_taap_2012_04_028 crossref_primary_10_3390_ijms20143418 crossref_primary_10_1016_j_scitotenv_2022_158652 crossref_primary_10_1289_EHP13018 crossref_primary_10_1016_j_apjtb_2017_09_001 crossref_primary_10_1371_journal_pone_0151225 crossref_primary_10_1038_s41598_017_15163_5 crossref_primary_10_1016_j_toxrep_2016_07_002 crossref_primary_10_1016_j_microc_2012_08_013 crossref_primary_10_1177_0748233712463778 crossref_primary_10_1007_s11356_018_1792_x crossref_primary_10_1016_j_scitotenv_2019_05_042 crossref_primary_10_1016_j_tox_2015_02_008 crossref_primary_10_1007_s12011_023_03577_4 crossref_primary_10_1039_C8MT00321A crossref_primary_10_1016_j_heha_2022_100004 crossref_primary_10_1016_j_toxrep_2015_09_003 crossref_primary_10_1007_s12011_017_1052_9 crossref_primary_10_1002_ejic_201600160 crossref_primary_10_1007_s11356_021_14273_y crossref_primary_10_1016_j_etap_2024_104397 |
| Cites_doi | 10.1016/S0095-4543(05)70347-X 10.4049/jimmunol.165.8.4290 10.1007/s00128-008-9471-0 10.1080/15298669091370293 10.1093/mutage/gem010 10.1186/1476-069X-9-36 10.1093/ije/27.5.871 10.1158/1055-9965.EPI-07-2816 10.1177/0748233708094096 10.1289/ehp.02110119 10.1016/j.scitotenv.2010.10.001 10.1289/ehp.9686 10.1016/j.taap.2006.12.032 10.1080/13547500500087913 10.1007/BF02784067 10.1016/j.cbi.2008.07.001 10.1016/j.taap.2003.10.020 10.3390/ijerph2005030002 10.1021/es702316k 10.1034/j.1600-0773.2001.d01-128.x 10.1016/j.mrfmmm.2003.07.009 10.5580/26a0 10.1093/carcin/8.6.803 10.1161/01.CIR.0000015862.64816.B2 10.1375/twin.10.5.757 10.1089/15230860260196236 10.1093/toxsci/kfh265 10.1002/(SICI)1098-2280(1998)32:4<301::AID-EM3>3.0.CO;2-I 10.1016/j.taap.2004.08.025 10.1093/aje/kwj154 10.1289/ehp.00108393 10.1016/j.scitotenv.2007.12.028 10.1097/01.ALC.0000128229.23396.42 10.1016/j.mrrev.2006.02.001 10.1039/b406573p 10.1016/j.taap.2003.10.016 10.1093/jn/137.12.2798 10.1016/0009-9120(93)90123-N 10.1056/NEJM197204062861404 10.1002/aheh.200390025 10.1186/1476-069X-6-4 10.1016/j.taap.2006.12.029 10.1016/j.taap.2007.02.007 10.1007/BF00316119 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2011 BioMed Central Ltd. Copyright ©2011 Islam et al; licensee BioMed Central Ltd. 2011 Islam et al; licensee BioMed Central Ltd. |
| Copyright_xml | – notice: COPYRIGHT 2011 BioMed Central Ltd. – notice: Copyright ©2011 Islam et al; licensee BioMed Central Ltd. 2011 Islam et al; licensee BioMed Central Ltd. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 5PM ABSHZ ADTPV AOWAS D8T DF6 ZZAVC DOA |
| DOI | 10.1186/1476-069X-10-64 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic PubMed Central (Full Participant titles) SWEPUB Högskolan i Skövde full text SwePub SwePub Articles SWEPUB Freely available online SWEPUB Högskolan i Skövde SwePub Articles full text DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 1476-069X |
| EndPage | 64 |
| ExternalDocumentID | oai_doaj_org_article_ae1ee2a254284224af6a010e9a68133a oai_DiVA_org_his_5533 PMC3146918 oai_biomedcentral_com_1476_069X_10_64 A262903629 21740555 10_1186_1476_069X_10_64 |
| Genre | Research Support, Non-U.S. Gov't Evaluation Study Journal Article |
| GeographicLocations | Bangladesh Sweden Malaysia |
| GeographicLocations_xml | – name: Bangladesh – name: Malaysia – name: Sweden |
| GroupedDBID | --- 0R~ 29G 2VQ 2WC 2XV 4.4 4P2 53G 5GY 5VS 6PF 7X7 7XC 88E 8C1 8FE 8FG 8FH 8FI 8FJ A8Z AAFWJ AAJSJ AASML AAWTL AAYXX ABDBF ABJCF ABUWG ACGFO ACGFS ACIHN ACIWK ACPRK ACUHS ADBBV ADFRT ADRAZ ADUKV AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHBYD AHMBA AHSBF AHYZX ALIPV ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS ATCPS BAPOH BAWUL BCNDV BENPR BFQNJ BGLVJ BHPHI BMC BPHCQ BVXVI C1A C6C CCPQU CITATION CS3 DIK E3Z EAD EAP EAS EBD EBLON EBS ECGQY EJD EMB EMK EMOBN ESX F5P FYUFA GROUPED_DOAJ GX1 H13 HCIFZ HMCUK HYE IAO IEP IHR INH INR IPNFZ ITC ITG ITH KQ8 L6V L7B M1P M48 M7S M~E O5R O5S OK1 OVT PATMY PGMZT PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO PTHSS PYCSY RBZ RIG RNS ROL RPM RSV SEV SOJ SV3 TR2 TUS U2A UKHRP WOQ WOW XSB -5A -5G -A0 -BR 3V. ACRMQ ADINQ C24 CGR CUY CVF ECM EIF FRP NPM PMFND 7X8 PPXIY PQGLB ABVAZ AFGXO AFNRJ ESTFP 5PM PJZUB ABSHZ ADTPV AOWAS D8T DF6 ZZAVC PUEGO |
| ID | FETCH-LOGICAL-b620t-bf476d19a7a786ea6773fca74b9bb847770a1b4f0ddab2549930b5f1f73ae76a3 |
| IEDL.DBID | RBZ |
| ISSN | 1476-069X |
| IngestDate | Wed Aug 27 01:30:42 EDT 2025 Thu Aug 21 06:45:24 EDT 2025 Thu Aug 21 18:31:17 EDT 2025 Wed May 22 07:16:52 EDT 2024 Fri Jul 11 08:06:59 EDT 2025 Tue Jun 17 21:41:58 EDT 2025 Tue Jun 10 20:34:04 EDT 2025 Wed Feb 19 02:08:01 EST 2025 Tue Jul 01 02:00:17 EDT 2025 Thu Apr 24 23:12:14 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| License | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-b620t-bf476d19a7a786ea6773fca74b9bb847770a1b4f0ddab2549930b5f1f73ae76a3 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Undefined-1 ObjectType-Feature-3 content type line 23 |
| OpenAccessLink | http://dx.doi.org/10.1186/1476-069X-10-64 |
| PMID | 21740555 |
| PQID | 880717158 |
| PQPubID | 23479 |
| PageCount | 1 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_ae1ee2a254284224af6a010e9a68133a swepub_primary_oai_DiVA_org_his_5533 pubmedcentral_primary_oai_pubmedcentral_nih_gov_3146918 biomedcentral_primary_oai_biomedcentral_com_1476_069X_10_64 proquest_miscellaneous_880717158 gale_infotracmisc_A262903629 gale_infotracacademiconefile_A262903629 pubmed_primary_21740555 crossref_primary_10_1186_1476_069X_10_64 crossref_citationtrail_10_1186_1476_069X_10_64 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2011-07-08 |
| PublicationDateYYYYMMDD | 2011-07-08 |
| PublicationDate_xml | – month: 07 year: 2011 text: 2011-07-08 day: 08 |
| PublicationDecade | 2010 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | Environmental health |
| PublicationTitleAlternate | Environ Health |
| PublicationYear | 2011 |
| Publisher | BioMed Central Ltd BioMed Central BMC |
| Publisher_xml | – name: BioMed Central Ltd – name: BioMed Central – name: BMC |
| References | A Santra (454_CR48) 2007; 220 JP Buchet (454_CR49) 1984; 55 454_CR31 MA Rothschild (454_CR32) 1972; 286 MM Khan (454_CR13) 2003; 4 K Hossain (454_CR24) 2000; 165 C Ferreccio (454_CR58) 2006; 24 DJ Thomas (454_CR8) 2004; 198 BGS (British Geological Survey) and DPHE (Department of Public Health Engineering, Bangladesh) (454_CR12) 2010 IARC (International Agency for Research on Cancer) (454_CR4) 2004 JM Paakkanen (454_CR45) 1998; 32 A Vahidnia (454_CR15) 2008; 176 D Chakraborti (454_CR1) 2004; 6 I Leclercq (454_CR55) 1999; 62 M Bissen (454_CR2) 2003; 31 R Scheig (454_CR34) 1996; 23 S Stranges (454_CR56) 2004; 28 N Nilima (454_CR52) 2010; 3 JR Meliker (454_CR19) 2007; 2 M Bissen (454_CR3) 2003 E Schmidt (454_CR33) 1993; 26 CH Wang (454_CR14) 2002; 105 TG Rossman (454_CR26) 2003; 533 AA Akhand (454_CR25) 2002; 4 JL Mumford (454_CR17) 2007; 115 MR Karagas (454_CR43) 1996; 5 R Colognato (454_CR23) 2007; 22 MT Schmitt (454_CR44) 2005; 10 A Van Green (454_CR40) 2008; 42 MR Karim (454_CR36) 2010; 409 AH Nabi (454_CR38) 2005; 2 KL Chen (454_CR46) 1999; 67 TG Rossman (454_CR7) 2004; 198 X Cui (454_CR22) 2004; 82 DJ Thomas (454_CR47) 2007; 222 F Bertolero (454_CR5) 1987; 8 Y-S Zhou (454_CR29) 2002; 21 J Liaw (454_CR30) 2008; 17 DNG Mazumder (454_CR20) 1998; 27 X Li (454_CR21) 2008; 81 H Ahsan (454_CR41) 2006; 163 DNG Mazumder (454_CR37) 2005; 206 B Agahian (454_CR42) 1990; 51 ME Vahter (454_CR57) 2007; 137 IAA Ismail (454_CR51) 2006 S Tapio (454_CR18) 2006; 612 RP Middelberg (454_CR54) 2007; 10 N Ali (454_CR35) 2010; 9 AG Gault (454_CR50) 2008; 393 S Sambu (454_CR9) 2008; 24 WHO (454_CR10) 2010 M Vahter (454_CR6) 2001; 89 CJ Chen (454_CR16) 2007; 222 J Liu (454_CR28) 2002; 110 I Morańska (454_CR53) 2004; 57 UK Chowdhury (454_CR11) 2000; 108 DN Liu (454_CR27) 1992; 31 454_CR39 |
| References_xml | – volume: 23 start-page: 551 year: 1996 ident: 454_CR34 publication-title: Prim Care doi: 10.1016/S0095-4543(05)70347-X – volume: 4 start-page: 7 year: 2003 ident: 454_CR13 publication-title: Asian Pac J Cancer Prev – volume: 165 start-page: 4290 year: 2000 ident: 454_CR24 publication-title: J Immunol doi: 10.4049/jimmunol.165.8.4290 – volume: 81 start-page: 406 year: 2008 ident: 454_CR21 publication-title: Bull Environ Contam Toxicol doi: 10.1007/s00128-008-9471-0 – volume: 51 start-page: 646 year: 1990 ident: 454_CR42 publication-title: Am Ind Hyg Assoc J doi: 10.1080/15298669091370293 – start-page: 269 volume-title: Monographs on evaluation of carcinogenic risk to humans. In: Some Drinking Water Disinfectants and Contaminants, including Arsenic year: 2004 ident: 454_CR4 – volume: 22 start-page: 255 year: 2007 ident: 454_CR23 publication-title: Mutagenesis doi: 10.1093/mutage/gem010 – volume-title: Arsenic in drinking water resulting in arsenic toxicity in India and Bangladesh year: 2010 ident: 454_CR10 – volume: 9 start-page: 36 year: 2010 ident: 454_CR35 publication-title: Environ Health doi: 10.1186/1476-069X-9-36 – volume: 27 start-page: 871 year: 1998 ident: 454_CR20 publication-title: Int J Epidemio doi: 10.1093/ije/27.5.871 – volume: 17 start-page: 1982 year: 2008 ident: 454_CR30 publication-title: Cancer Epidemiol Biomarkers Prev doi: 10.1158/1055-9965.EPI-07-2816 – volume: 24 start-page: 217 year: 2008 ident: 454_CR9 publication-title: Toxicol Ind Health doi: 10.1177/0748233708094096 – volume: 110 start-page: 119 year: 2002 ident: 454_CR28 publication-title: Environ Health Perspect doi: 10.1289/ehp.02110119 – volume: 409 start-page: 278 year: 2010 ident: 454_CR36 publication-title: Sci Total Environ doi: 10.1016/j.scitotenv.2010.10.001 – volume: 115 start-page: 690 year: 2007 ident: 454_CR17 publication-title: Environ Health Perspect doi: 10.1289/ehp.9686 – volume: 222 start-page: 298 year: 2007 ident: 454_CR16 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2006.12.032 – volume: 10 start-page: 95 year: 2005 ident: 454_CR44 publication-title: Biomarkers doi: 10.1080/13547500500087913 – volume: 67 start-page: 109 year: 1999 ident: 454_CR46 publication-title: Biol Trace Elem Res doi: 10.1007/BF02784067 – volume: 176 start-page: 188 year: 2008 ident: 454_CR15 publication-title: Chem Biol Interact doi: 10.1016/j.cbi.2008.07.001 – start-page: 97 volume-title: Arsenic - a review. Part-II: Oxidation of arsenic and its removal in water treatment year: 2003 ident: 454_CR3 – volume: 198 start-page: 319 year: 2004 ident: 454_CR8 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2003.10.020 – volume: 2 start-page: 385 year: 2005 ident: 454_CR38 publication-title: Int J Environ Res Public Health doi: 10.3390/ijerph2005030002 – volume: 42 start-page: 2283 year: 2008 ident: 454_CR40 publication-title: Environmental Science and Technology doi: 10.1021/es702316k – volume: 89 start-page: 1 year: 2001 ident: 454_CR6 publication-title: Pharmacol Toxico doi: 10.1034/j.1600-0773.2001.d01-128.x – volume: 533 start-page: 37 year: 2003 ident: 454_CR26 publication-title: Mutat Res doi: 10.1016/j.mrfmmm.2003.07.009 – start-page: 10 volume-title: J Al-Aqsa Unv year: 2006 ident: 454_CR51 – ident: 454_CR39 doi: 10.5580/26a0 – volume: 31 start-page: 560 year: 1992 ident: 454_CR27 publication-title: Chin J Med – volume: 8 start-page: 80 year: 1987 ident: 454_CR5 publication-title: Carcinogenesis doi: 10.1093/carcin/8.6.803 – volume: 105 start-page: 1804 year: 2002 ident: 454_CR14 publication-title: Circulation doi: 10.1161/01.CIR.0000015862.64816.B2 – volume: 3 start-page: 284 year: 2010 ident: 454_CR52 publication-title: Al Ame en J Med Sci – volume: 5 start-page: 849 year: 1996 ident: 454_CR43 publication-title: Cancer Epidemiol Biomarkers Prev – volume: 10 start-page: 757 year: 2007 ident: 454_CR54 publication-title: Twin Res Hum Genet doi: 10.1375/twin.10.5.757 – volume: 24 start-page: 164 year: 2006 ident: 454_CR58 publication-title: J Health Popul Nutr – volume: 4 start-page: 445 year: 2002 ident: 454_CR25 publication-title: Antioxid Redox Signal doi: 10.1089/15230860260196236 – volume: 82 start-page: 478 year: 2004 ident: 454_CR22 publication-title: Toxicol Sci doi: 10.1093/toxsci/kfh265 – volume: 32 start-page: 301 year: 1998 ident: 454_CR45 publication-title: Environ Mol Mutagen doi: 10.1002/(SICI)1098-2280(1998)32:4<301::AID-EM3>3.0.CO;2-I – volume: 206 start-page: 169 year: 2005 ident: 454_CR37 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2004.08.025 – volume: 163 start-page: 1138 year: 2006 ident: 454_CR41 publication-title: Am J Epidemiol doi: 10.1093/aje/kwj154 – volume: 108 start-page: 393 year: 2000 ident: 454_CR11 publication-title: Environ Health Perspect doi: 10.1289/ehp.00108393 – volume: 393 start-page: 168 year: 2008 ident: 454_CR50 publication-title: Sci Total Environ doi: 10.1016/j.scitotenv.2007.12.028 – volume: 28 start-page: 949 year: 2004 ident: 454_CR56 publication-title: Alcohol Clin Exp Res doi: 10.1097/01.ALC.0000128229.23396.42 – volume: 612 start-page: 215 year: 2006 ident: 454_CR18 publication-title: Mutat Res doi: 10.1016/j.mrrev.2006.02.001 – volume-title: Arsenic Contamination of Groundwater in Bangladesh year: 2010 ident: 454_CR12 – volume: 62 start-page: 16 year: 1999 ident: 454_CR55 publication-title: Acta Gastroenterol Belg – volume: 6 start-page: 74 year: 2004 ident: 454_CR1 publication-title: J Environ Monit doi: 10.1039/b406573p – volume: 57 start-page: 427 year: 2004 ident: 454_CR53 publication-title: Wiad Lek – volume: 198 start-page: 394 year: 2004 ident: 454_CR7 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2003.10.016 – volume: 137 start-page: 2798 year: 2007 ident: 454_CR57 publication-title: J Nutr doi: 10.1093/jn/137.12.2798 – volume: 26 start-page: 241 year: 1993 ident: 454_CR33 publication-title: Clin Biochem doi: 10.1016/0009-9120(93)90123-N – ident: 454_CR31 – volume: 286 start-page: 748 year: 1972 ident: 454_CR32 publication-title: N Engl J Med doi: 10.1056/NEJM197204062861404 – volume: 21 start-page: 484 year: 2002 ident: 454_CR29 publication-title: Chin J Endemiol – volume: 31 start-page: 9 year: 2003 ident: 454_CR2 publication-title: Acta Hydrochim Hydrobiol doi: 10.1002/aheh.200390025 – volume: 2 start-page: 4 year: 2007 ident: 454_CR19 publication-title: Environ Health doi: 10.1186/1476-069X-6-4 – volume: 220 start-page: 146 year: 2007 ident: 454_CR48 publication-title: Toxicol and Applied Pharm doi: 10.1016/j.taap.2006.12.029 – volume: 222 start-page: 365 year: 2007 ident: 454_CR47 publication-title: Toxicol Appl Pharmacol doi: 10.1016/j.taap.2007.02.007 – volume: 55 start-page: 151 year: 1984 ident: 454_CR49 publication-title: Arch Toxicol doi: 10.1007/BF00316119 |
| SSID | ssj0017865 |
| Score | 2.2686913 |
| Snippet | Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs) showing a... Background Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs)... BACKGROUND: Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs)... Background: Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests (LFTs)... Abstract Background Chronic arsenic exposure has been shown to cause liver damage. However, serum hepatic enzyme activity as recognized on liver function tests... |
| SourceID | doaj swepub pubmedcentral biomedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 64 |
| SubjectTerms | Adult Alanine Transaminase - blood Alkaline Phosphatase - blood Arsenic Arsenic - analysis Arsenic Poisoning - blood Arsenic Poisoning - epidemiology Aspartate Aminotransferases - blood Bangladesh - epidemiology Biomarkers - blood Cross-Sectional Studies Dose-response relationship (Biochemistry) Dose-Response Relationship, Drug Environmental Monitoring Enzymes Epidemiological Monitoring Female Hair - chemistry Health aspects Humans Liver - enzymology Liver function tests Liver Function Tests - methods Male Middle Aged Nails - chemistry Natural sciences Naturvetenskap Physiological aspects Water Pollutants, Chemical - analysis Water Pollutants, Chemical - poisoning Water Supply - analysis |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV1Lb9QwELZQD4gL4k1KQT5UgktonIedwGlLqSqkcqJob5adjLWRttnVZlcC_hR_kRknWdWtEBeusT3xYzIznzP-zNhxWjooUiViAwnEuUshRqeHYEXVjZN0JljQ4eTLr_LiKv8yL-Y3rvqinLCBHniYuBMDAiA1iGPQkKK_MU4axBBQGVkivvKhEfq8CUyN_w9U6S-RFLlCvCyr-UjqI0p5sn9GFkjePui-DPyTp_G_a6xveKvbmZQB36j3UeeP2MMxuOSzYVCP2T3onrD7l-Pv86fs99mqh3gzpMUC30yJcIt2zceELY5AF7q25vBjvaLdQ266hmOUyFFXd9ccul8_r6HnGOvyJeV0cPKMJIVj0Lrtedv52u3-oFc_iAKUspqkf-CG-_Gj1HrYjeSe6Jaanxq6WKSBfvGMXZ1__vbpIh5vbIitTJNtbB1ObiMqowyuABipVOZqo3JbWYt-UKnECJu7pGmM9dA0S2zhhFOZASVN9pwddKsOXjKOLjVBCUVpMaisZVJWrhYZYMBWCiGditjHYN30emDn0MSXHZbgp6tp1TWtukbUI_OIvZ9WWdcjGTrdybHUHhSV8m6Dd_sG05v-WvWU1CbokH-Aaq1Htdb_UuuIvSWl02RmsGO1GU9L4OQQYZeepTKtKPqoInYU1ETzUAfFfFJbTUWUU9fBatdrtNyI5UVRRuzFoMX7LhNOJSa4iKlAv4MxhSVdu_Dk5Bm63kqgzOPhSwianLXfZ34aFm2vC0Qah_9jrl6xB8NOv4qT8ogdbDc7eI2h4ta-8VbhDzx8aQM priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrR3LbtQw0IIiIS6ovEML8qESXFLiPOwEhNCWUlVIy4lFe7OcZNKNtE2Wza7U8lP8IjNOdovbcuMa2xNnZjwPZx6MHYRpBUmohG8gAD-uQvBR6aGzooqykpQTLCg5efxNnk7ir9NketUOaEBgd6trR_2kJsv54cXPy0944D_aA5_KdyJW6BXLbEoyRcZ32T1US4raGYzjq18KKrV9JbeThzo_twC4lvs-d1SWrex_U37_pcCuB1c6JUit2jrZZQ8He5OPegZ5xO5A85jdHw9_1J-w38dtB_6yj5QFvtzExs3qBR9iuDgiCJq64HCxaOlCkZum5Gg4cmTf9TmH5tflOXQczV8-pzAPTsqSoHC0Y1cdrxs7u97mfnU9KEAo7Qb6e264_X6EWvQXlNzWvqXlR4Z6jZTQzZ6yycmX759P_aGJg5_LMFj5eYXILUVmlEEKgJFKRVVhVJxneY6qUanAiDyugrI0ufVWoyBPKlGpyICSJnrGdpq2gReMo5YNEEKS5mhnFjJIs6oQEaANlwohK-WxDw7d9KIv2KGphLY7gqdZE9U1UV2jIyRjjx1uqKyLoT46temYa-snpfLmgrfbBZs3_XPqEbGNsyH7oF2e6UFEaAMCIDSIAzQZ0LIylTToLUNmZCqiyHjsDTGdprOAGyvMkECByKEaXnoUyjAjgyTz2L4zEyVG4QzzDdtqGqIwuwbadadRmKN7L5LUY897Lt5umVxXKg7nMeXwt_NN7khTz2y98gi1cSYQ5kF_Epwlx_WPkUXDrO50gs7Hy_-Bqz32oL_8V36Q7rOd1XINr9B6XOWvrVT4A5SAcD4 priority: 102 providerName: Scholars Portal |
| Title | Dose-response relationship between arsenic exposure and the serum enzymes for liver function tests in the individuals exposed to arsenic: a cross sectional study in Bangladesh |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/21740555 https://www.proquest.com/docview/880717158 http://dx.doi.org/10.1186/1476-069X-10-64 https://pubmed.ncbi.nlm.nih.gov/PMC3146918 https://urn.kb.se/resolve?urn=urn:nbn:se:his:diva-5533 https://doaj.org/article/ae1ee2a254284224af6a010e9a68133a |
| Volume | 10 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lj9MwELbYXQlxQbwJLJUPK8ElEOdhO3Bqd7eskLpCiEUVF8tJJmqkblo1rQT8Kf4iM05aSBdOXHyI7YnjmczMZ4_HjJ2EuoQkVMK3EIAflyH4aPQQrKi8KCWdCRZ0OHlyKS-u4g_TZPo7WfTeDr7Q8o2IFWJemU5JY8j4gB2FMeI5Auajr7sNA6XdrZG7xl0Wn78Q2DvZPu8ZJJe3_6Z2_sM87YdO9hKMOqM0vsfudt4kH7bsv89uQf2A3Z50--UP2c-zRQP-qo2DBb7aRr7NqiXvIrQ4Iluoq5zDt-WClgu5rQuObiFH4dxcc6h_fL-GhqNzy-cUxMHJFBIVjl7quuFV7VpXu5NdTUsKkMpiS_0tt9x9P1LN2-VH7jLbUveRpZtECmhmj9jV-Pzz6YXfXdHgZzIM1n5W4uQWIrXKIgfASqWiMrcqztIsQ8OnVGBFFpdBUdjMYdEoyJJSlCqyoKSNHrPDelHDU8bRhgZIIdEZepG5DHRa5iIC9NC0ELJUHnvX45tZtuk4DCXI7tfgv2qI64a4bhDmyNhjr7dcNnmX_Zwu4Zgbh4K0vNnh1a7D9k3_bDoisekNyD1AMTadAjAWBEBocQ7QIUC_yZbSIhaG1Eotosh67CUJnSG9ggPLbXc8AieHMnSZYSjDlNyN1GPHvZaoD_JeNd-KraEqCqKrYbFpDKpqBO8i0R570krxbsgETCn1m8dUT75739SvqauZy0Yeoa1NBdI8af-EXpez6svQTcOsakyC0OLZf3HxObvTrukrP9DH7HC92sALdArX2YAdqKnCUp8KKsfvB-xodH758dPALbNgOYn1wCmNX0W7aA8 |
| linkProvider | BioMedCentral |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELZKkYAL4k2ggA-V4JIS52EncNqlVAt099SiiovlJGM20jZZbXYl4E_xFxk7yWrdwolrbE9sz2Qe8cxnQg7DVEMSCuYrCMCPdQg-Gj0MVkRRam5qgpkpTp7O-OQ8_nyRXOyR2VALs1PepRZdKeDRbiH6wmrvIWms--ZT_pbFAgNjnl0YtcLjG-SmSBJh67nG37anCiK1V0tuO_dQP38hcKX8feFYLQvuf12F79iwq_mVDgqptVwn98jd3uWko24198ke1A_IrWl_qP6Q_D5uWvBXXbIs0NWQHjevlrRP46IY_kJdFRR-LBvzT5GquqToO1KU4M0lhfrXz0toKXrAdGEyPaixl4YKRVd23dKqtr2rbflX25ECpNIM1N9RRe36kWrR_aOkFv7WDB8rc91ICe38ETk_-Xj2YeL39zj4OQ-DtZ9r3NySZUoo5AAoLkSkCyXiPMtztI5CBIrlsQ7KUuU2YI2CPNFMi0iB4Cp6TPbrpoanhKKhDZBCkuboahY8SDNdsAjQjUsZ41p45L3DN7nsMDukQdF2W1COpOG6NFyXGAvx2CNHA5dl0UOkm5s6FtKGSim_PuDNdsDwpn92HRuxcSZkHzSr77KXZ6mAAYQK9wC9BnSulOYKA2bIFE9ZFCmPvDZCJ43ywYkVqq-hwM0xMF5yFPIwMz5J5pEDpycqjcJppoPYStNkMu1qaDatRH2OET5LUo886aR4O2UTvRp8OI8IR76dNbktdTW3kOURGuSMIc3D7ktwhhxXX0d2G-ZVKxOMP579FxdfkduTs-mpPP00-_Kc3OkOAYQfpAdkf73awAv0Itf5S6sa_gAtvnRM |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV1Lb9QwELZKkSouiHcDBXyoBJe0cR52AqddllV5tCBE0YqL5SQ2G5Emq82uBPwp_iIzTrLatHDiFsX2JPGM5xHPfCbk0I-NjnzBXKU97YbG1y4YPQhWRJYbjjXBDIuTT8_4yXn4dhbNdsiHvhZmq7xLlW0p4NF2IXpptTdcZN-PF7lpF33Mj1koIDLmyQz1Cg-vkesiigQeafBp_HWzrSBie7bkpnOH9fMXApfq38uB2bLo_ld1-JYRu5xgOYAhtaZreovc7HxOOmqF5DbZ0dUdsnfa7arfJb8ndaPdZZstq-myz4-bFwva5XFRiH91VWRU_1jU-FORqiqn4DxSEOH1BdXVr58XuqHgAtMSUz0oGkykQsGXXTW0qGzvYlP_1bSkNFCpe-ovqKL2-4Fq1v6kpBb_FoePFZ43kutmfo-cT19_fnXidgc5uCn3vZWbGpjcnCVKKOCAVlyIwGRKhGmSpmAehfAUS0Pj5blKbcQaeGlkmBGB0oKr4D7ZrepK7xMKltYDClGcgq-ZcS9OTMYCDX5czBg3wiEvB3yTixa0QyKM9rAFBEki1yVyXUIwxEOHHPVcllmHkY5HdZTSxkoxvzrg-WZA_6R_dh2j2AxeyN6ol99kpyak0kxrX8EcgNsA3pUyXEHErBPFYxYEyiHPUOgkah9cBKorooDJQRwvOfK5n6BTkjjkYNATtEY2aKa92EpswlS7StfrRoJChxCfRbFDHrRSvHllDF8RIM4hYiDfg28atlTF3GKWB2CREwY0D9uVMBgyKb6M7DTMi0ZGEIA8_C8uPiV7HydT-f7N2btH5Ea7CSBcLz4gu6vlWj8GL3KVPrGa4Q97qXQX |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Dose-response+relationship+between+arsenic+exposure+and+the+serum+enzymes+for+liver+function+tests+in+the+individuals+exposed+to+arsenic%3A+a+cross+sectional+study+in+Bangladesh&rft.jtitle=Environmental+health&rft.au=Hossain+Mostaque&rft.au=Sultana+Papia&rft.au=Karim+Rezaul&rft.au=Rahman+Mashiur&rft.date=2011-07-08&rft.pub=BMC&rft.issn=1476-069X&rft.eissn=1476-069X&rft.volume=10&rft.issue=1&rft.spage=64&rft_id=info:doi/10.1186%2F1476-069X-10-64&rft.externalDBID=DOA&rft.externalDocID=oai_doaj_org_article_ae1ee2a254284224af6a010e9a68133a |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1476-069X&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1476-069X&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1476-069X&client=summon |