Risks of adverse pregnancy and birth outcomes in women treated or not treated with mood stabilisers for bipolar disorder: population based cohort study

• Published in: BMJ (Online) Vol. 345; no. 7883; p. 18
• Main Authors: Bodén, Robert, Lundgren, Maria, Brandt, Lena, Reutfors, Johan, Andersen, Morten, Kieler, Helle
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 08.11.2012; BMJ Publishing Group; BMJ Publishing Group LTD; BMJ Publishing Group Ltd
• Subjects: Adult; Analysis of Variance; Anticonvulsants; Antipsychotic Agents - adverse effects; Antipsychotic Agents - therapeutic use; Antipsychotics; Bipolar disorder; Bipolar Disorder - complications; Bipolar Disorder - diagnosis; Bipolar Disorder - drug therapy; Birth; Child and Adolescent Psychiatry; Child and Adolescent Psychiatry (Paedatrics); Child Health; Cohort analysis; Cohort Studies; Congenital Abnormalities - epidemiology; Congenital Abnormalities - etiology; Congenital defects; Diabetes mellitus; Diabetes, Gestational - epidemiology; Diabetes, Gestational - etiology; Drugs: Psychiatry; Epidemiologic Studies; Female; Gestational age; Health risk assessment; Humans; Incidence; Infant, Newborn; Infant, Small for Gestational Age; Infants; Lithium; Medicin och hälsovetenskap; Menstruation; Mental health outcomes; Metabolic Disorders; Microcephaly; Mood; Mood disorders; Mood Disorders (Including Depression); Morbidity; Neonates; Odds Ratio; Population studies; Population-based studies; Pregnancy; Pregnancy Complications - chemically induced; Pregnancy Complications - epidemiology; Pregnancy Outcome; Pregnancy, High-Risk; Premature birth; Premature Birth - epidemiology; Premature Birth - etiology; Prenatal Exposure Delayed Effects - chemically induced; Psychotic Disorders (Incl Schizophrenia); Psychotropic drugs; Reference Values; Registries; Reproductive Medicine; Risk Assessment; Small for gestational age; Sweden; Womens health; Sweden

Objective To investigate the risks of adverse pregnancy and birth outcomes for treated and untreated bipolar disorder during pregnancy.Design Population based cohort study using data from national health registers.Setting Sweden.Participants 332 137 women with a last menstrual period anytime after 1...