Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis

• Published in: BMC genomics Vol. 10; no. 1; p. 54
• Main Authors: Ward, Philip N, Holden, Matthew T G, Leigh, James A, Lennard, Nicola, Bignell, Alexandra, Barron, Andy, Clark, Louise, Quail, Michael A, Woodward, John, Barrell, Bart G, Egan, Sharon A, Field, Terence R, Maskell, Duncan, Kehoe, Michael, Dowson, Christopher G, Chanter, Neil, Whatmore, Adrian M, Bentley, Stephen D, Parkhill, Julian
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 28.01.2009; BioMed Central; BMC
• Subjects: Adaptation, Biological - genetics; Animals; Bacterial Proteins - genetics; Bacterial Proteins - metabolism; Cattle; Comparative Genomic Hybridization; Diseases; DNA, Bacterial - genetics; Evolution, Molecular; Gene Expression Profiling; Genes, Bacterial; Genetic aspects; Genome, Bacterial; Genomic Islands; Mastitis, Bovine - microbiology; Phylogeny; Physiological aspects; Sequence Analysis, DNA; Streptococcus; Streptococcus - genetics; Streptococcus - metabolism; Streptococcus - pathogenicity; Virulence; United Kingdom

Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland. Comparative analysis of the complete genome sequence of S. uber...