Goat milk with and without increased concentrations of lysozyme improves repair of intestinal cell damage induced by enteroaggregative Escherichia coli

• Published in: BMC gastroenterology Vol. 12; no. 1; p. 106
• Main Authors: Carvalho, Eunice B, Maga, Elizabeth A, Quetz, Josiane S, Lima, Ila F N, Magalhães, Hemerson Y F, Rodrigues, Felipe A R, Silva, Antônio V A, Prata, Mara M G, Cavalcante, Paloma A, Havt, Alexandre, Bertolini, Marcelo, Bertolini, Luciana R, Lima, Aldo A M
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.08.2012; BioMed Central; BMC
• Subjects: Animal genetic engineering; Animals; Animals, Genetically Modified; Apoptosis; Apoptosis - drug effects; Bacteria; Bacterial Adhesion - drug effects; Bacterial infections; Cell Line, Tumor; Cell Movement - drug effects; Cell Proliferation - drug effects; Cell Survival - drug effects; Cells; Cells migration; Cells proliferation; Cells viability; Cells, Cultured; Colon cancer; Diarrhea; Dose-Response Relationship, Drug; EAEC adherence; Epithelium - drug effects; Epithelium - microbiology; Epithelium - pathology; Escherichia coli; Escherichia coli - drug effects; Escherichia coli - isolation & purification; Escherichia coli - physiology; Gastroenterology; Genetically modified animals; Goat's milk; Goats; Health aspects; Humans; In Vitro Techniques; Intestinal cells; Intestines - drug effects; Intestines - microbiology; Intestines - pathology; Lysozyme; Milk; Milk - enzymology; Muramidase - genetics; Muramidase - pharmacology; Physiological aspects; Proteins; Rats; Small intestine; Studies; Brazil; United States

Enteroaggregative Escherichia coli (EAEC) causes diarrhea, malnutrition and poor growth in children. Human breast milk decreases disease-causing bacteria by supplying nutrients and antimicrobial factors such as lysozyme. Goat milk with and without human lysozyme (HLZ) may improve the repair of intes...