Adherence to antihypertensive treatment and associated factors among patients on follow up at University of Gondar Hospital, Northwest Ethiopia
Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the...
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Published in | BMC public health Vol. 12; no. 1; p. 282 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
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BioMed Central Ltd
10.04.2012
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Abstract | Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital.
Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16.
More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence.
Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. |
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AbstractList | BACKGROUND: Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. METHOD: Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. RESULTS: More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. CONCLUSION: Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. Abstract Background Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. Method Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. Results More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. Conclusion Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. BACKGROUNDHypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. METHODInstitution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. RESULTSMore than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. CONCLUSIONOnly 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. Doc number: 282 Abstract Background : Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. Method : Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. Results : More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. Conclusion : Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. Abstract Background Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in Addis Ababa. Poor adherence is associated with bad outcome of the disease and wastage of healthcare resources. In Ethiopia, particularly in the study area little is known about treatment adherence and associated factors. Therefore this study aimed to assess adherence to antihypertensive therapy and associated factors among HTN patients on follow up at University of Gondar Referral Hospital. Method Institution based cross sectional study was conducted. Systematic sampling technique was used to select 384 participants. A structured standard questionnaire was used after some modifications. Morisky Medication Adherence Scale was used for labeling patients as adherent or non-adherent. Data were entered and analyzed using SPSS version 16. Results More than half (64.6 %) of the study participants were found to be adherent to their treatment. Sex (AOR = 0.48, 95%CI = 0.28, 0.82), knowledge about HTN and its treatment (AOR = 6.21, 95%CI = 3.22, 11.97), distance from the hospital (AOR = 2.02, 95% CI =1.19-3.43) and co morbidity (AOR = 2.5, 95%CI = 1.01, 6.21) variables were found significantly associated with treatment adherence. Conclusion Only 64.6% of the study subjects were found to be adherent to their treatment. Factors such as sex, distance from the hospital, number of co morbidities, Knowledge about HTN and its treatment were associated with adherence behavior of patients. Early diagnosis and management of co morbidities, adherence counseling and patient education about the disease and its treatment are important to improve adherence status of patients. |
ArticleNumber | 282 |
Audience | Academic |
Author | Mengesha, Zelalem Birhanu Alemie, Getahun Asres W/Yohannes, Solomon Meseret Ambaw, Abere Dessie |
AuthorAffiliation | 1 College of Medicine and Health Sciences, University of Gondar, Gondar, P.O.Box 196, Ethiopia 2 Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, P.O.Box 196, Ethiopia 3 Department of Reproductive Health, Institute of Public Health, University of Gondar, Gondar, P.O.Box 196, Ethiopia |
AuthorAffiliation_xml | – name: 1 College of Medicine and Health Sciences, University of Gondar, Gondar, P.O.Box 196, Ethiopia – name: 2 Department of Epidemiology and Biostatistics, Institute of Public Health, University of Gondar, Gondar, P.O.Box 196, Ethiopia – name: 3 Department of Reproductive Health, Institute of Public Health, University of Gondar, Gondar, P.O.Box 196, Ethiopia |
Author_xml | – sequence: 1 givenname: Abere Dessie surname: Ambaw fullname: Ambaw, Abere Dessie – sequence: 2 givenname: Getahun Asres surname: Alemie fullname: Alemie, Getahun Asres – sequence: 3 givenname: Solomon Meseret surname: W/Yohannes fullname: W/Yohannes, Solomon Meseret – sequence: 4 givenname: Zelalem Birhanu surname: Mengesha fullname: Mengesha, Zelalem Birhanu |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/22490130$$D View this record in MEDLINE/PubMed |
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Copyright | COPYRIGHT 2012 BioMed Central Ltd. 2012 Ambaw et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Copyright ©2012 Ambaw et al.; licensee BioMed Central Ltd. 2012 Ambaw et al.; licensee BioMed Central Ltd. |
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PublicationDate_xml | – month: 04 year: 2012 text: 2012-04-10 day: 10 |
PublicationDecade | 2010 |
PublicationPlace | England |
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PublicationTitle | BMC public health |
PublicationTitleAlternate | BMC Public Health |
PublicationYear | 2012 |
Publisher | BioMed Central Ltd BioMed Central BMC |
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References_xml | – volume: 24 start-page: 1187 issue: 6 year: 2006 ident: 4082_CR7 publication-title: J Hypertens doi: 10.1097/01.hjh.0000226210.95936.bc contributor: fullname: P Primatesta – volume: 8 start-page: 579 issue: 4–5 year: 2002 ident: 4082_CR16 publication-title: East Mediterr Health J contributor: fullname: Y Rm – volume: 22 start-page: 11 issue: 1 year: 2004 ident: 4082_CR13 publication-title: J Hypertens doi: 10.1097/00004872-200401000-00003 contributor: fullname: PM Kearney – volume: 43 start-page: 517 issue: 6 year: 2005 ident: 4082_CR9 publication-title: Med Care doi: 10.1097/01.mlr.0000166617.68751.5f contributor: fullname: R Balkrishnan – volume: 290 start-page: 199 issue: 2 year: 2003 ident: 4082_CR3 publication-title: JAMA doi: 10.1001/jama.290.2.199 contributor: fullname: I Hajjar – volume: 14 start-page: 489 issue: 8 year: 2000 ident: 4082_CR14 publication-title: J Hum Hypertens doi: 10.1038/sj.jhh.1001050 contributor: fullname: MA van der Sande – volume: 9 start-page: 8 issue: s1 year: 2001 ident: 4082_CR15 publication-title: Int J Pharm Pract doi: 10.1111/j.2042-7174.2001.tb01068.x contributor: fullname: C Lennon – volume: 365 start-page: 217 issue: 9455 year: 2005 ident: 4082_CR1 publication-title: Lancet doi: 10.1016/S0140-6736(05)70151-3 contributor: fullname: PM Kearney – volume: 24 start-page: 67 issue: 1 year: 1986 ident: 4082_CR10 publication-title: Med Care doi: 10.1097/00005650-198601000-00007 contributor: fullname: DE Morisky – volume: 42 start-page: 1206 issue: 6 year: 2003 ident: 4082_CR2 publication-title: Hypertension doi: 10.1161/01.HYP.0000107251.49515.c2 contributor: fullname: AV Chobanian – volume: 15 start-page: 997 issue: 6 year: 1993 ident: 4082_CR4 publication-title: Clin Exp Hypertens doi: 10.3109/10641969309037087 contributor: fullname: LA Salako – volume: 19 start-page: 357 issue: 4 year: 2004 ident: 4082_CR18 publication-title: Curr Opin Cardiol doi: 10.1097/01.hco.0000126978.03828.9e contributor: fullname: M Krousel-Wood – volume: 12 start-page: 243 issue: 3 year: 2005 ident: 4082_CR19 publication-title: Eur J Cardiovasc Prev Rehabil doi: 10.1097/00149831-200506000-00010 contributor: fullname: E Yiannakopoulou – volume: 49 start-page: 69 year: 2006 ident: 4082_CR6 publication-title: Hypertension doi: 10.1161/01.HYP.0000252676.46043.18 contributor: fullname: KL Ong – volume: 2 start-page: 146 issue: 2 year: 2001 ident: 4082_CR11 publication-title: HIV Clin Trials doi: 10.1310/89E2-XNJL-W107-R2GL contributor: fullname: RJ Pratt – volume: 9 start-page: 39 year: 2009 ident: 4082_CR5 publication-title: BMC Cardiovasc Disord doi: 10.1186/1471-2261-9-39 contributor: fullname: F Tesfaye – volume: 5 start-page: 6 year: 2006 ident: 4082_CR17 publication-title: Ann Gen Psychiatr doi: 10.1186/1744-859X-5-6 contributor: fullname: B Baune – volume: 2 start-page: e280 issue: 3 year: 2007 ident: 4082_CR8 publication-title: PLoS One doi: 10.1371/journal.pone.0000280 contributor: fullname: SK Hashmi – volume: 20 start-page: 295 issue: 4 year: 2006 ident: 4082_CR12 publication-title: J Hum Hypertens doi: 10.1038/sj.jhh.1001981 contributor: fullname: ME Inkster |
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Snippet | Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and 30% in... Abstract Background Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in... Background Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia... Doc number: 282 Abstract Background : Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is... BACKGROUNDHypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia and... BACKGROUND: Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in Ethiopia... Abstract Background Hypertension is an overwhelming global challenge with high morbidity and mortality rates. The prevalence of HTN is estimated to be 6% in... |
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SubjectTerms | Adolescent Adult Analysis Antihypertensive Agents - economics Antihypertensive Agents - therapeutic use Antihypertensive drugs Antihypertensives Blood pressure Blood Pressure - physiology Care and treatment Chronic Disease - epidemiology Chronic illnesses Comorbidity Confidence intervals Counseling Cross-Sectional Studies Data collection Drug therapy Ethiopia Ethiopia - epidemiology Ethnic Groups - psychology Ethnic Groups - statistics & numerical data Female Follow-Up Studies Health aspects Health care policy Health Knowledge, Attitudes, Practice Hospitals, University Humans Hypertension Hypertension - diagnosis Hypertension - drug therapy Hypertension - epidemiology Logistic Models Male Medical referrals Medication Adherence - psychology Medication Adherence - statistics & numerical data Middle Aged Mortality Patient compliance Patient education Patients Population Prevalence Prevalence studies (Epidemiology) Public health Quality of life Questionnaires Sociodemographics Socioeconomic Factors Surveys and Questionnaires Teaching hospitals Young Adult |
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Title | Adherence to antihypertensive treatment and associated factors among patients on follow up at University of Gondar Hospital, Northwest Ethiopia |
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