MyBASE: a database for genome polymorphism and gene function studies of Mycobacterium
Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphism...
Saved in:
| Published in | BMC microbiology Vol. 9; no. 1; p. 40 |
|---|---|
| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
BioMed Central Ltd
20.02.2009
BioMed Central BMC |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1471-2180 1471-2180 |
| DOI | 10.1186/1471-2180-9-40 |
Cover
Loading…
| Abstract | Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations.
We have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE.
As an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn. |
|---|---|
| AbstractList | BACKGROUND: Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations. DESCRIPTION: We have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE. CONCLUSION: As an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn. Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations. We have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE. As an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn. Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations.BACKGROUNDMycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations.We have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE.DESCRIPTIONWe have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE.As an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn.CONCLUSIONAs an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn. Abstract Background Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and subsequent control strategies will be greatly accelerated. It has been suggested that genome polymorphisms, namely large sequence polymorphisms, can influence the pathogenicity of different mycobacterial strains. However, there is currently no database dedicated to mycobacterial genome polymorphisms with functional interpretations. Description We have developed a mycobacterial database (MyBASE) housing genome polymorphism data and gene functions to provide the mycobacterial research community with a useful information resource and analysis platform. Whole genome comparison data produced by our lab and the novel genome polymorphisms identified were deposited into MyBASE. Extensive literature review of genome polymorphism data, mainly large sequence polymorphisms (LSPs), operon predictions and curated annotations of virulence and essentiality of mycobacterial genes are unique features of MyBASE. Large-scale genomic data integration from public resources makes MyBASE a comprehensive data warehouse useful for current research. All data is cross-linked and can be graphically viewed via a toolbox in MyBASE. Conclusion As an integrated platform focused on the collection of experimental data from our own lab and published literature, MyBASE will facilitate analysis of genome structure and polymorphisms, which will provide insight into genome evolution. Importantly, the database will also facilitate the comparison of virulence factors among various mycobacterial strains. MyBASE is freely accessible via http://mybase.psych.ac.cn. |
| Audience | Academic |
| Author | Zhu, Xinxing Yu, Xuping Zhu, Baoli Chang, Suhua Gao, George F Fang, Kechi Wu, Zuowei Cui, Sijia Liu, Jun Wang, Jing Yang, Huanming |
| AuthorAffiliation | 5 Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310029, PR China 3 Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada 4 Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China 1 James D Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310007, PR China 2 Behavioral Genetics Center, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, PR China 6 Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, PR China |
| AuthorAffiliation_xml | – name: 6 Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100029, PR China – name: 5 Institute of Preventive Veterinary Medicine, College of Animal Sciences, Zhejiang University, Hangzhou 310029, PR China – name: 1 James D Watson Institute of Genome Sciences of Zhejiang University, Hangzhou 310007, PR China – name: 2 Behavioral Genetics Center, Institute of Psychology, Chinese Academy of Sciences, Beijing 100101, PR China – name: 4 Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, PR China – name: 3 Department of Molecular Genetics, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada |
| Author_xml | – sequence: 1 givenname: Xinxing surname: Zhu fullname: Zhu, Xinxing – sequence: 2 givenname: Suhua surname: Chang fullname: Chang, Suhua – sequence: 3 givenname: Kechi surname: Fang fullname: Fang, Kechi – sequence: 4 givenname: Sijia surname: Cui fullname: Cui, Sijia – sequence: 5 givenname: Jun surname: Liu fullname: Liu, Jun – sequence: 6 givenname: Zuowei surname: Wu fullname: Wu, Zuowei – sequence: 7 givenname: Xuping surname: Yu fullname: Yu, Xuping – sequence: 8 givenname: George F surname: Gao fullname: Gao, George F – sequence: 9 givenname: Huanming surname: Yang fullname: Yang, Huanming – sequence: 10 givenname: Baoli surname: Zhu fullname: Zhu, Baoli – sequence: 11 givenname: Jing surname: Wang fullname: Wang, Jing |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/19228437$$D View this record in MEDLINE/PubMed |
| BookMark | eNp1kt1r1TAYxotM3IfeeikFQdhFj0mbJq0XwnFMPbAhOHcd3uajy2ibsySVnf_e1M7DqpNcJLx5nh_Pm7zHycFgB5UkrzFaYVzR95gwnOW4QlmdEfQsOdoXDh6dD5Nj728Rwqwq2IvkENd5XpGCHSXXl7tP66vzDymkEgI04FWqrUtbNdhepVvb7XrrtjfG9ykMcqpHwTiIYOyQ-jBKo3xqdXq5E7YBEZQzY_8yea6h8-rVw36SXH8-_3H2Nbv49mVztr7IGoqLkElMYoiKFlDKQmgCoqZVnlOopWalRKSuUaOJKhvBdEMAQyEBM6GqvGSUNcVJspm50sIt3zrTg9txC4b_LljXcnDBiE7xaCoLAbVCTBEtVN2UTGNMMNFVWck8sj7OrO3Y9EoKNQQH3QK6vBnMDW_tT57Tkpa4iID1DGiM_Q9geSNsz6cv4tMX8ZoTFBnvHkI4ezcqH3hvvFBdB4Oyo-eUoYJSNqV9OwtbiM2ZQduIFJOYr3FdMoQImyKtnlDFJVVvRJwkbWJ9YThdGKImqPvQwug931x9X2rfPH6wfaN_hisKyCwQznrvlObCBJgGJ6YwHceITzP87xus_rLtyU8bfgHmIfER |
| CitedBy_id | crossref_primary_10_1016_j_tube_2011_02_005 crossref_primary_10_14232_abs_2023_2_203_220 crossref_primary_10_3389_fbioe_2020_00607 crossref_primary_10_1371_journal_pone_0036094 crossref_primary_10_14232_abs_2021_65_233_245 crossref_primary_10_1016_j_biotechadv_2011_06_008 crossref_primary_10_1016_j_meegid_2011_08_019 crossref_primary_10_1093_database_bau082 crossref_primary_10_1134_S1068162012040139 crossref_primary_10_1093_database_bas032 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2009 BioMed Central Ltd. Copyright ©2009 Zhu et al; licensee BioMed Central Ltd. 2009 Zhu et al; licensee BioMed Central Ltd. |
| Copyright_xml | – notice: COPYRIGHT 2009 BioMed Central Ltd. – notice: Copyright ©2009 Zhu et al; licensee BioMed Central Ltd. 2009 Zhu et al; licensee BioMed Central Ltd. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM ISR 7X8 5PM DOA |
| DOI | 10.1186/1471-2180-9-40 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Science in Context MEDLINE - Academic PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ : directory of open access journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1471-2180 |
| EndPage | 40 |
| ExternalDocumentID | oai_doaj_org_article_ce853ca9e07e4fce9b57f11414f858d2 PMC2656513 oai_biomedcentral_com_1471_2180_9_40 A195700473 19228437 10_1186_1471_2180_9_40 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | China |
| GeographicLocations_xml | – name: China |
| GroupedDBID | --- 0R~ 23N 2VQ 2WC 4.4 53G 5VS 6J9 7X7 88E 8FE 8FH 8FI 8FJ A8Z AAFWJ AAJSJ AASML AAYXX ABDBF ABUWG ACGFO ACGFS ACIHN ACPRK ACUHS ADBBV ADRAZ ADUKV AEAQA AENEX AEUYN AFKRA AFPKN AFRAH AHBYD AHMBA AHSBF AHYZX ALIPV ALMA_UNASSIGNED_HOLDINGS AMKLP AMTXH AOIJS BAPOH BAWUL BBNVY BCNDV BENPR BFQNJ BHPHI BMC BPHCQ BVXVI C1A C6C CCPQU CITATION CS3 DIK DU5 E3Z EAD EAP EAS EBD EBLON EBS EJD EMB EMK EMOBN ESX F5P FYUFA GROUPED_DOAJ GX1 H13 HCIFZ HMCUK HYE IAO IGS IHR INH INR IPNFZ ISR ITC KQ8 LK5 LK8 M1P M48 M7P M7R MM. M~E O5R O5S OK1 OVT P2P PGMZT PHGZM PHGZT PIMPY PQQKQ PROAC PSQYO RBZ RIG RNS ROL RPM RSV SBL SOJ SV3 TR2 TUS UKHRP W2D WOQ WOW XSB ~02 CGR CUY CVF ECM EIF NPM PJZUB PPXIY PQGLB PMFND 7X8 -A0 3V. ABVAZ ACRMQ ADINQ AFGXO AFNRJ AGJBV C24 ESTFP 5PM PUEGO |
| ID | FETCH-LOGICAL-b613t-d14437863a5d3cf4ac968226a9df75d04990bf4e5bc7fb4a1a3da17ce825767b3 |
| IEDL.DBID | RBZ |
| ISSN | 1471-2180 |
| IngestDate | Wed Aug 27 01:30:30 EDT 2025 Thu Aug 21 13:39:35 EDT 2025 Wed May 22 07:12:47 EDT 2024 Fri Jul 11 07:43:30 EDT 2025 Tue Jun 17 22:21:20 EDT 2025 Tue Jun 10 21:27:51 EDT 2025 Fri Jun 27 05:35:12 EDT 2025 Mon Jul 21 06:03:41 EDT 2025 Tue Jul 01 04:31:09 EDT 2025 Thu Apr 24 23:10:47 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 1 |
| Language | English |
| License | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-b613t-d14437863a5d3cf4ac968226a9df75d04990bf4e5bc7fb4a1a3da17ce825767b3 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | http://dx.doi.org/10.1186/1471-2180-9-40 |
| PMID | 19228437 |
| PQID | 67036672 |
| PQPubID | 23479 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_ce853ca9e07e4fce9b57f11414f858d2 pubmedcentral_primary_oai_pubmedcentral_nih_gov_2656513 biomedcentral_primary_oai_biomedcentral_com_1471_2180_9_40 proquest_miscellaneous_67036672 gale_infotracmisc_A195700473 gale_infotracacademiconefile_A195700473 gale_incontextgauss_ISR_A195700473 pubmed_primary_19228437 crossref_citationtrail_10_1186_1471_2180_9_40 crossref_primary_10_1186_1471_2180_9_40 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2009-02-20 |
| PublicationDateYYYYMMDD | 2009-02-20 |
| PublicationDate_xml | – month: 02 year: 2009 text: 2009-02-20 day: 20 |
| PublicationDecade | 2000 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | BMC microbiology |
| PublicationTitleAlternate | BMC Microbiol |
| PublicationYear | 2009 |
| Publisher | BioMed Central Ltd BioMed Central BMC |
| Publisher_xml | – name: BioMed Central Ltd – name: BioMed Central – name: BMC |
| References | 15659067 - Cell Microbiol. 2005 Feb;7(2):233-44 11234002 - Nature. 2001 Feb 22;409(6823):1007-11 17342140 - Nat Med. 2007 Mar;13(3):286-7 14681438 - Nucleic Acids Res. 2004 Jan 1;32(Database issue):D377-82 11891304 - Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3684-9 15749894 - J Immunol. 2005 Mar 15;174(6):3570-9 15928073 - Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8327-32 17488849 - Nucleic Acids Res. 2007;35(11):3654-67 12595424 - Infect Immun. 2003 Mar;71(3):1134-40 15608225 - Nucleic Acids Res. 2005 Jan 1;33(Database issue):D399-402 17984080 - Nucleic Acids Res. 2008 Jan;36(Database issue):D539-42 18032431 - Nucleic Acids Res. 2008 Jan;36(Database issue):D469-74 17433778 - Tuberculosis (Edinb). 2007 Jul;87(4):347-59 15722376 - Bioinformatics. 2005 May 15;21(10):2563-5 17360388 - Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5157-62 11606763 - Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12712-7 15608233 - Nucleic Acids Res. 2005 Jan 1;33(Database issue):D438-41 17890243 - Nucleic Acids Res. 2008 Jan;36(Database issue):D836-41 15024109 - Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4865-70 18835847 - Nucleic Acids Res. 2009 Jan;37(Database issue):D499-508 17254314 - BMC Bioinformatics. 2006;7 Suppl 5:S9 16381881 - Nucleic Acids Res. 2006 Jan 1;34(Database issue):D335-7 10592175 - Nucleic Acids Res. 2000 Jan 1;28(1):33-6 15701760 - Nucleic Acids Res. 2005;33(3):880-92 14987770 - FEMS Microbiol Lett. 2004 Feb 16;231(2):237-45 12657046 - Mol Microbiol. 2003 Apr;48(1):77-84 14569030 - Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12989-94 18793412 - BMC Genomics. 2008;9:413 15998914 - Genome Res. 2005 Jul;15(7):1015-22 17785835 - J Immunol. 2007 Sep 15;179(6):3973-81 15479716 - Bioinformatics. 2005 Feb 15;21(4):537-9 14557547 - Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12420-5 17658950 - PLoS Pathog. 2007 Jul;3(7):e110 14756778 - Mol Microbiol. 2004 Jan;51(2):359-70 9381173 - Science. 1997 Oct 24;278(5338):631-7 17065465 - Nucleic Acids Res. 2007 Jan;35(Database issue):D376-80 18681951 - BMC Genomics. 2008;9:373 10348738 - Science. 1999 May 28;284(5419):1520-3 17005003 - Immunology. 2006 Oct;119(2):224-31 16755503 - Genet Mol Res. 2006;5(1):115-26 15342607 - J Bacteriol. 2004 Sep;186(18):6332-4 9634230 - Nature. 1998 Jun 11;393(6685):537-44 18186793 - Mol Microbiol. 2008 Feb;67(3):672-84 12857778 - Clin Microbiol Rev. 2003 Jul;16(3):463-96 17360408 - Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5145-50 17984072 - Nucleic Acids Res. 2008 Jan;36(Database issue):D543-6 17372194 - Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5596-601 11282970 - Genome Res. 2001 Apr;11(4):547-54 17906132 - Microbiology. 2007 Oct;153(Pt 10):3323-36 12788972 - Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7877-82 |
| References_xml | – reference: 15024109 - Proc Natl Acad Sci U S A. 2004 Apr 6;101(14):4865-70 – reference: 14557547 - Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12420-5 – reference: 10348738 - Science. 1999 May 28;284(5419):1520-3 – reference: 10592175 - Nucleic Acids Res. 2000 Jan 1;28(1):33-6 – reference: 17658950 - PLoS Pathog. 2007 Jul;3(7):e110 – reference: 17890243 - Nucleic Acids Res. 2008 Jan;36(Database issue):D836-41 – reference: 18835847 - Nucleic Acids Res. 2009 Jan;37(Database issue):D499-508 – reference: 12595424 - Infect Immun. 2003 Mar;71(3):1134-40 – reference: 17984080 - Nucleic Acids Res. 2008 Jan;36(Database issue):D539-42 – reference: 12657046 - Mol Microbiol. 2003 Apr;48(1):77-84 – reference: 17984072 - Nucleic Acids Res. 2008 Jan;36(Database issue):D543-6 – reference: 14987770 - FEMS Microbiol Lett. 2004 Feb 16;231(2):237-45 – reference: 17785835 - J Immunol. 2007 Sep 15;179(6):3973-81 – reference: 18793412 - BMC Genomics. 2008;9:413 – reference: 17906132 - Microbiology. 2007 Oct;153(Pt 10):3323-36 – reference: 17488849 - Nucleic Acids Res. 2007;35(11):3654-67 – reference: 9634230 - Nature. 1998 Jun 11;393(6685):537-44 – reference: 16381881 - Nucleic Acids Res. 2006 Jan 1;34(Database issue):D335-7 – reference: 16755503 - Genet Mol Res. 2006;5(1):115-26 – reference: 17360408 - Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5145-50 – reference: 15722376 - Bioinformatics. 2005 May 15;21(10):2563-5 – reference: 15659067 - Cell Microbiol. 2005 Feb;7(2):233-44 – reference: 15701760 - Nucleic Acids Res. 2005;33(3):880-92 – reference: 15608225 - Nucleic Acids Res. 2005 Jan 1;33(Database issue):D399-402 – reference: 11891304 - Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3684-9 – reference: 17342140 - Nat Med. 2007 Mar;13(3):286-7 – reference: 15342607 - J Bacteriol. 2004 Sep;186(18):6332-4 – reference: 15479716 - Bioinformatics. 2005 Feb 15;21(4):537-9 – reference: 15928073 - Proc Natl Acad Sci U S A. 2005 Jun 7;102(23):8327-32 – reference: 17005003 - Immunology. 2006 Oct;119(2):224-31 – reference: 17254314 - BMC Bioinformatics. 2006;7 Suppl 5:S9 – reference: 17433778 - Tuberculosis (Edinb). 2007 Jul;87(4):347-59 – reference: 11282970 - Genome Res. 2001 Apr;11(4):547-54 – reference: 14756778 - Mol Microbiol. 2004 Jan;51(2):359-70 – reference: 15749894 - J Immunol. 2005 Mar 15;174(6):3570-9 – reference: 14681438 - Nucleic Acids Res. 2004 Jan 1;32(Database issue):D377-82 – reference: 12857778 - Clin Microbiol Rev. 2003 Jul;16(3):463-96 – reference: 9381173 - Science. 1997 Oct 24;278(5338):631-7 – reference: 18681951 - BMC Genomics. 2008;9:373 – reference: 17360388 - Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5157-62 – reference: 18186793 - Mol Microbiol. 2008 Feb;67(3):672-84 – reference: 18032431 - Nucleic Acids Res. 2008 Jan;36(Database issue):D469-74 – reference: 15998914 - Genome Res. 2005 Jul;15(7):1015-22 – reference: 11606763 - Proc Natl Acad Sci U S A. 2001 Oct 23;98(22):12712-7 – reference: 17065465 - Nucleic Acids Res. 2007 Jan;35(Database issue):D376-80 – reference: 12788972 - Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7877-82 – reference: 11234002 - Nature. 2001 Feb 22;409(6823):1007-11 – reference: 14569030 - Proc Natl Acad Sci U S A. 2003 Oct 28;100(22):12989-94 – reference: 15608233 - Nucleic Acids Res. 2005 Jan 1;33(Database issue):D438-41 – reference: 17372194 - Proc Natl Acad Sci U S A. 2007 Mar 27;104(13):5596-601 |
| SSID | ssj0017837 |
| Score | 1.918613 |
| SecondaryResourceType | review_article |
| Snippet | Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial pathogenesis and... BACKGROUND: Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on mycobacterial... Abstract Background Mycobacterial pathogens are a major threat to humans. With the increasing availability of functional genomic data, research on... |
| SourceID | doaj pubmedcentral biomedcentral proquest gale pubmed crossref |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 40 |
| SubjectTerms | Computational Biology Databases, Genetic Genes, Bacterial Genetic aspects Genetic polymorphisms Genome, Bacterial Genomics Mycobacteria Mycobacterium Mycobacterium - genetics Mycobacterium - pathogenicity Online databases Polymorphism, Genetic Virulence |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3da9wwDDejMNjL2PduazczBnsKjeOvpG_X0dINbg_rDvpmFMfeCndJ2d093H9fKcl1Z8rYy14tQWxJtqRY_omxjyZXoBo0XmVzAtX2JgMDIhMWyrISALqgx8mzb-Zirr5e6au9Vl9UEzbAAw-CO6a2mtJDFXIbVPShqrWNGMQLFUtdNv3piz5vl0yN9we27NEyBR69GTqxfIRrFKU5vhvLqox-eSTv3BeJe-pR_O-f1XvOKi2k3PNM50_Y4zGk5NNhKU_Zg9A-Yw-HJpPb52w-255OL89OOHAqByW3xTFS5YTOugz8pltg-o_Svl4tObQNjSMDujtSGV8NdYa8i3y29bj5e3DnzfIFm5-f_fh8kY3NFLIaPfY6azBzkrY0EnQjfVTgK4PBgYGqiVY3lPnkdVRB197GWoEA2YCwKH5KSWwtX7KDtmvDa8ZzA6oupLVBgyqsBeFrXSGPjUGVqpiwk0Sm7mYAznAEZZ1ScFc5UogjhbjKqXzCsp0CnB9hyqlbxsL16Upp7vF_uuPffedvnKekz2Q2_QCamxvNzf3L3CbsA1mDI-iMlmpzfsJmtXJfLr-7qaj6ZgFW4pxGptjh3D2MTx1QfIS2lXAeJpy4t31Cfr8zOkckKohrQ7dZOUPAacbifF4NJvhn8VWBIYe0E2YT40zWnVLa6189sHiBwb0W8s3_ENRb9mi4eCvwID5kB-vfm3CE8du6ftdv1VvGSUBu priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Journals: Open Access dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3db9MwELdgCIkXxDeFARZC4ikQJ46dTEKoQ5sGUnlgVNqbdXHsMalNRtNK9L_nLknXmQKv9kU5--58d_L5d4y9UbEEWaHySh0TqLZVESgQkdCQ54UAyBJ6nDz5qk6m8stZdratfxo2sP1rakf9pKaL2btfP9cf0eA_dAafq_cCD9gIXVUcFZgO3WS30CtpauMwkdsbBZ13-JlXtAOA4-73f7x8nwUOq8P13z29r7mvsLTymq86vsfuDkEmH_dacZ_dcPUDdrtvO7l-yKaT9eH49OiAA6cCUXJkHGNXTnitc8cvm9l63uD-X7RzDnVF40iADpCEyNu-8pA3nk_WFo-DDu55NX_EpsdH3z-dREN7hahEH76MKsylUp2rFLIqtV6CLRSGCwqKyuusolwoLr10WWm1LyUISCsQ2rqckhRdpo_ZXt3U7injsQJZJqnWLgOZaA3CllmBNNo7mctkxA6CPTWXPZSGIXDrcAbtzJBADAnEFEbGIxZtBGDsAFxO_TNmpktgcrVD__aKfvOff1EekjwDbrqBZnFuBss11Nc1tVC4WDvprSvKTHvMIoX0eZZXuLbXpA2GwDRqqtY5h1Xbms-n38xYFF37AJ0iTwORb5B3C8PjB9w-wt8KKPcDSrR2G0y_2iidoSkqkatds2qNIig1pZGfJ70KbhdfJBiEpHrEdKCcwbrDmfriRwc1nmC4n4n02f-Zes7u9JdsCR66-2xvuVi5FxirLcuXnRH-BtUyOSc priority: 102 providerName: Scholars Portal |
| Title | MyBASE: a database for genome polymorphism and gene function studies of Mycobacterium |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/19228437 https://www.proquest.com/docview/67036672 http://dx.doi.org/10.1186/1471-2180-9-40 https://pubmed.ncbi.nlm.nih.gov/PMC2656513 https://doaj.org/article/ce853ca9e07e4fce9b57f11414f858d2 |
| Volume | 9 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwELfYJiReEN8URrEQEk8RceL4nL21qNNA6oQ6KlW8WI7jwKQ2nWj70P-euyTt5lU88ZKH-KLYvjvfnX3-HWMfVSytLFF4JcQEqu1UZJUVkQCrdS6szRK6nDy-VBdT-W2WzW73O-6d4AutPgtcPiM0RHGUY7BzxE4SCZKKNEyGP_fnBaAbdMw9bQfPePj9vXvt88AcNaj9h2vzHeMUJk7esUTnT9jjzoXkg5bnT9kDXz9jD9uiktvnbDreDgdXozNuOaV_kpni6JlyQmNdeH6znGO4j7N7vVpwW5f0HgnQvBGL-KrNK-TLio-3DpW9AXPeLF6w6fnox5eLqCueEBVooddRiZFSClqlNitTV0nrcoXOgLJ5WUFWUqQTF5X0WeGgKqQVNi2tAOc1hSBQpC_Zcb2s_WvGY2VlkaQAPrMyAbDCFVmONFB5qWXSY2fBnJqbFijDEHR12IJaZIghhhhiciPjHot2DDCugyWn6hhz04QnWh3Qf9rT7_7zL8oh8TPoTfMCpct0emmoamvqbO5j8LJyPi8yqDBGFLLSmS5xbB9IGgxBZdSUi_PLblYr8_VqYgYib4oDQIp96oiqJfbd2e5qA04foWsFlKcBJeqyC5rf74TOUBMlwNV-uVkZRUBpCrA_r1oRvB18nqCLkUKPQSCcwbjDlvr6dwMknqAzn4n0zf_w7y171B6wJbjgnrLj9Z-Nf4d-2rrosyOYQZ-dDEeX3yf9ZrcDn2Op-43y_gWsrDv1 |
| linkProvider | BioMedCentral |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwELdgCMEL4nMUBrMQEk-BOPFHsrcWbepg3cO2ShMvluM4o1KTTEv70P-euyTtaiqeeLUviu0734d89ztCPsuQG56D8HIVIqi2lYGRhgVMmSRJmTEiwuLkybkcT_mPa3HdQwphLUxW2nJ2D0H0dbsIfd5q7nXCWHffE_mNgX4NwFKFQQrR0EPySAmh8I5ejH5tHhRU0sJnbmh7_Mbd7_8qfJ979qqF9d9V3lvWy8-s3DJVJ8_Js97HpMNuCy_IA1e9JI-7rpOrV2Q6WY2Gl8dH1FDMD0U7RsF1pQjXWjp6W89XZQ3HP2tKaqocx4EA7B_ykDZd4iGtCzpZWdAGLdrzsnxNpifHV9_HQd9dIcjAhC-CHEKpWCUyNiKPbcGNTSV4C9KkeaFEjqFQmBXcicyqIuOGmTg3TFmXYIyisvgN2avqyr0lNJSGZ1GslBOGR0oZZjORAo0qHE94NCBH3pnq2w5JQyO2tT8DHNbIEI0M0anm4YAEawZo2-OWY_uMuW7jl0Tu0H_Z0K__8y_KEfLTW007UN_d6F7MNLZ1ja1JXagcL6xLM6EKCCIZLxKR5LC3TygNGrE0KkzWuTHLptGnlxd6yNK2e4CKYU09UVHD2q3pax_g-BB-y6M88Cjhsltv-nAtdBqnMEOucvWy0RKR1KSC9ex3Ini_-TQCHyRWA6I84fT27c9Us98t0ngE3r5g8bv_4d8heTK-mpzps9Pzn-_J0-41LgLtfED2FndL9wGcukX2sb2ufwDvRUgq |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3db9MwELdgCMQL4puOwSyExFNYPhw72VsLqzagE2JUmnixbMce1ZqkWtuH_vfcJWlXU_HEWxRfFNt3vg_57neEvOchU6wA4WUiRFBtwwPFVRREQmVZHimVxlicPDrnp2P25TK97PKfsBZGl6ac3EIQfdwuQp82mhsezPXRrHDtgc_4UQQKNgBTFQY5hEN3yT2BuFIYuQ9-bW4URNbgZ25oOwDH3e__qnyfegarwfXf1d5b5stPrdyyVcPH5FHnZNJ-KxVPyB1bPSX327aTq2dkPFoN-hcnx1RRTBBFQ0bBd6WI11paOqunq7KG_Z_MS6qqAt8DARhAZCKdt5mHtHZ0tDKgDhq452X5nIyHJz8_nQZde4VAgw1fBAXEUonIeKLSIjGOKZNzcBe4ygsn0gJjoVA7ZlNthNNMRSopVCSMzTBIETp5QfaqurKvCA25YjpOhLCpYrEQKjI6zYFGOMsyFvfIsbenctZCaUgEt_ZHgMUSGSKRITKXLOyRYM0AaTrgcuyfMZVNAJPxHfoPG_r1f_5FOUB-erNpXtQ3V7I7uRL7uiZG5TYUljljc50KB1FkxFyWZgWs7R1Kg0QwjQqzda7Ucj6XZxc_ZD_Km_YBIoE5dUSuRgFWXfEDbB_ib3mUBx4lnHbjDR-uhU7iEKbIVbZeziVHKDUuYD4vWxG8XXwegxOSiB4RnnB66_ZHqsnvBmo8Bnc_jZL9_-HfIXnw_fNQfjs7__qaPGxv42LQzgdkb3GztG_AqVvot81p_QNWikf1 |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=MyBASE%3A+a+database+for+genome+polymorphism+and+gene+function+studies+of+Mycobacterium&rft.jtitle=BMC+microbiology&rft.au=Zhu%2C+Xinxing&rft.au=Chang%2C+Suhua&rft.au=Fang%2C+Kechi&rft.au=Cui%2C+Sijia&rft.date=2009-02-20&rft.pub=BioMed+Central+Ltd&rft.issn=1471-2180&rft.eissn=1471-2180&rft.volume=9&rft.spage=40&rft_id=info:doi/10.1186%2F1471-2180-9-40&rft.externalDocID=A195700473 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1471-2180&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1471-2180&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1471-2180&client=summon |