A randomized trial of sodium-restriction on kidney function, fluid volume and adipokines in CKD patients

• Published in: BMC nephrology Vol. 15; no. 1; p. 57
• Main Authors: Campbell, Katrina L, Johnson, David W, Bauer, Judith D, Hawley, Carmel M, Isbel, Nicole M, Stowasser, Michael, Whitehead, Jonathan P, Dimeski, Goce, McMahon, Emma
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.04.2014; BioMed Central
• Subjects: Adipokines - blood; Aged; Albumin; Body Fluids - metabolism; Creatinine - blood; Diet; Diet, Sodium-Restricted - methods; Double-Blind Method; Female; Glomerular Filtration Rate; Health aspects; Hospitals; Humans; Male; Medical research; Molecular weight; Mortality; Natriuretic Peptide, Brain - blood; Nephrology; Peptide Fragments - blood; Renal Insufficiency, Chronic - diagnosis; Renal Insufficiency, Chronic - diet therapy; Renal Insufficiency, Chronic - physiopathology; Reproducibility of Results; Rodents; Sensitivity and Specificity; Sodium; Studies; Treatment Outcome; Canada; Queensland Australia; Australia

Dietary sodium restriction is a key management strategy in chronic kidney disease (CKD). Recent evidence has demonstrated short-term reduction in blood pressure (BP) and proteinuria with sodium restriction, however the effect on other cardiovascular-related risk factors requires investigation in CKD...