Weekend light shifts evoke persistent Drosophila circadian neural network desynchrony

• Published in: bioRxiv
• Main Authors: Nave, Ceazar, Roberts, Logan, Hwu, Patrick, Estrella, Jerson D, Vo, Thanh C, Nguyen, Thanh H, Pervolarakis, Nicholas, Shaw, Paul J, Leise, Tanya L, Holmes, Todd C
• Format: Paper
• Language: English
• Published: Cold Spring Harbor Cold Spring Harbor Laboratory Press 02.01.2020; Cold Spring Harbor Laboratory
• Edition: 1.1
• Subjects: Biological clocks; Bioluminescence; Circadian rhythms; Circuits; Drosophila; Entrainment; Insects; Learning; Light; Neural networks; Neuroscience; Oscillations; Period protein; Sleep; Suprachiasmatic nucleus; Synchronization

Billions of people subject themselves to phase-shifting light signals on a weekly basis by remaining active later at night and sleeping in later on weekends relative to weekday for up to a 3hr weekend light shift (WLS). Unnatural light signals disrupt circadian rhythms and physiology and behavior. R...