Insulin resistance and glycemic abnormalities are associated with deterioration of left ventricular diastolic function: a cross-sectional study

• Published in: Cardiovascular diabetology Vol. 9; no. 1; p. 63
• Main Authors: Dinh, Wilfried, Lankisch, Mark, Nickl, Werner, Scheyer, Daniel, Scheffold, Thomas, Kramer, Frank, Krahn, Thomas, Klein, Rolf M, Barroso, Michael Coll, Füth, Reiner
• Format: Journal Article
• Language: English
• Published: England BioMed Central 15.10.2010; BioMed Central Ltd; BMC
• Subjects: Aged; Biomarkers - blood; Blood Glucose - analysis; Cardiovascular disease; Chi-Square Distribution; Cross-Sectional Studies; Diabetes; Diabetes Mellitus, Type 2 - blood; Diabetes Mellitus, Type 2 - epidemiology; Diabetes Mellitus, Type 2 - physiopathology; Diastole; Echocardiography, Doppler; Female; Germany - epidemiology; Glucose Tolerance Test; Glycated Hemoglobin A - analysis; Humans; Insulin - blood; Insulin Resistance; Logistic Models; Male; Metabolic disorders; Middle Aged; Original Investigation; Prevalence; Risk Assessment; Risk Factors; Stroke Volume; Studies; Ventricular Dysfunction, Left - diagnostic imaging; Ventricular Dysfunction, Left - epidemiology; Ventricular Dysfunction, Left - physiopathology; Ventricular Function, Left

Left ventricular diastolic dysfunction (LVDD) is considered a precursor of diabetic cardiomyopathy, while insulin resistance (IR) is a precursor of type 2 diabetes mellitus (T2DM) and independently predicts heart failure (HF). We assessed whether IR and abnormalities of the glucose metabolism are re...