Body mass index and chronic unexplained gastrointestinal symptoms: an adult endoscopic population based study

• Published in: Gut Vol. 54; no. 10; pp. 1377 - 1383
• Main Authors: Aro, P, Ronkainen, J, Talley, N J, Storskrubb, T, Bolling-Sternevald, E, Agréus, L
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and British Society of Gastroenterology 01.10.2005; BMJ Publishing Group LTD; Copyright 2005 by Gut
• Subjects: Abdomen; abdominal symptom questionnaire; Antacids - therapeutic use; ASQ; BMI; Body Mass Index; Chronic Disease; Cohort Studies; dyspepsia; Endoscopy, Gastrointestinal - methods; epidemiology; Esophageal Sphincter, Lower - drug effects; Esophageal Sphincter, Lower - physiopathology; Esophagitis - complications; Esophagitis - epidemiology; Female; gastro-oesophageal reflux disease; gastro-oesophageal reflux symptoms; Gastroesophageal reflux; Gastroesophageal Reflux - epidemiology; Gastroesophageal Reflux - etiology; Gastroesophageal Reflux - physiopathology; gastrointestinal symptoms; GORD; GORS; Humans; IBS; identity number; irritable bowel syndrome; LOS; lower oesophageal sphincter; Male; Middle Aged; obesity; Obesity - complications; Obesity - epidemiology; Obesity - physiopathology; odds ratio; OEG; oesophagogastroduodenoscopy; population study; Population Surveillance - methods; Population-based studies; Pressure; Prevalence; questionnaires; Sweden - epidemiology; Sweden; United States > US

Background: We aimed to determine whether obese subjects experience more gastro-oesophageal reflux (GORS) symptoms than normal subjects, and further to determine if this association was explained by oesophagitis or medications that lower oesophageal sphincter pressure. Methods: In a representative S...