In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation

• Published in: Annals of the rheumatic diseases Vol. 83; no. 3; pp. 277 - 287
• Main Authors: Pertsinidou, Eleftheria, Saevarsdottir, Saedis, Manivel, Vivek Anand, Klareskog, Lars, Alfredsson, Lars, Mathsson-Alm, Linda, Hansson, Monika, Cornillet, Martin, Serre, Guy, Holmdahl, Rikard, Skriner, Karl, Jakobsson, Per-Johan, Westerlind, Helga, Askling, Johan, Rönnelid, Johan
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and European League Against Rheumatism 01.03.2024; Elsevier Limited; BMJ Publishing Group
• Subjects: Anti-Citrullinated Protein Antibodies; Antibodies; Arthritis; Arthritis, Rheumatoid; Autoantibodies; Autoimmune Diseases; C-reactive protein; Citrulline; Classification; Erythrocyte sedimentation rate; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Immunology; Inflammation; Isotypes; Joint diseases; Life Sciences; Patients; Peptides; Peptides, Cyclic; Rheumatoid; Rheumatoid Arthritis; Rheumatoid Factor; Rheumatology; Serology; Sweden; Autoantibodies; Anti-Citrullinated Protein Antibodies; Rheumatoid Factor; Autoimmune Diseases; Arthritis, Rheumatoid; Rheumatoid; Arthritis

ObjectivesTo investigate how individual rheumatoid arthritis (RA) autoantibodies associate with individual signs and symptoms at the time of RA diagnosis.MethodsIgA, IgG, IgM rheumatoid factor (RF), antibodies against cyclic citrullinated peptide version 2 (anti-CCP2) and 16 individual antibodies ag...