A large-scale association study identified multiple HLA-DRB1 alleles associated with ACPA-negative rheumatoid arthritis in Japanese subjects - Terao, Chikashi; Ohmura, Koichiro; Kochi, Yuta; Ikari, Katsunori; Maruya, Etsuko; Katayama, Masaki; Shimada, Kota; Murasawa, Akira; Honjo, Shigeru; Takasugi, Kiyoshi; Matsuo, Keitaro; Tajima, Kazuo; et al. (Annals of the rheumatic diseases, 2011)
Keywords: Adult; Aged; Arthritis, Rheumatoid - genetics; Autoantibodies - blood; Biological and medical sciences; Case-Control Studies; Consortia; Deoxyribonucleic acid; Diseases of the osteoarticular system; DNA; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genetic testing; Genotype; Histocompatibility Testing - methods; HLA-DRB1 Chains - genetics; Hospitals; Humans; Inflammatory joint diseases; Laboratories; Male; Medical sciences; Middle Aged; Peptides, Cyclic - immunology; Rheumatoid arthritis; Software; Statistical analysis; Studies; Japan; Human; Immunopathology; HLA-System; Allele; Chronic; Multiple; Rheumatoid arthritis; Diseases of the osteoarticular system; Rheumatology; Autoimmune disease; Inflammatory joint disease