Single-cell transcriptome analysis revealed a suppressive tumor immune microenvironment in EGFR mutant lung adenocarcinoma - Yang, Lei; He, Yun-Ting; Dong, Song; Wei, Xue-Wu; Chen, Zhi-Hong; Zhang, Bo; Chen, Wei-Dong; Yang, Xiao-Rong; Wang, Fen; Shang, Xue-Meng; Zhong, Wen-Zhao; Wu, Yi-Long; et al. (Journal for immunotherapy of cancer, 2022)
Keywords: Adenocarcinoma of Lung - genetics; Adenocarcinoma of Lung - pathology; Biomarkers, Tumor - metabolism; Cancer; Cancer therapies; Chemotherapy; Cytokines; Epidermal growth factor; ErbB Receptors - genetics; Female; Fibroblasts; Genes; Humans; Immune Checkpoint Inhibitors - pharmacology; Immune Checkpoint Inhibitors - therapeutic use; Immunotherapy; Immunotherapy - methods; Immunotherapy Biomarkers; Kinases; Lung cancer; lung neoplasms; Lung Neoplasms - genetics; Lung Neoplasms - pathology; Lymphocytes; Male; Mutation; Neutrophils; Ontology; Patients; Prognosis; Single-Cell Analysis - methods; Transcriptome - genetics; Tumor Microenvironment; lung neoplasms; immunotherapy; tumor microenvironment