Analysis of expression in the Anopheles gambiae developing testes reveals rapidly evolving lineage-specific genes in mosquitoes

• Published in: BMC genomics Vol. 10; no. 1; p. 300
• Main Authors: Krzywinska, Elzbieta, Krzywinski, Jaroslaw
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.07.2009; BioMed Central; BMC
• Subjects: Amino Acid Sequence; Animals; Anopheles; Anopheles - genetics; Antisense DNA; Comparative Genomic Hybridization; DNA, Complementary - genetics; Evolution, Molecular; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genes, Insect; Genetic aspects; Genetic transcription; Male; Molecular Sequence Data; Physiological aspects; Sequence Alignment; Sequence Analysis, DNA; Spermatogenesis; Spermatogenesis - genetics; Testis - metabolism; United Kingdom

Male mosquitoes do not feed on blood and are not involved in delivery of pathogens to humans. Consequently, they are seldom the subjects of research, which results in a very poor understanding of their biology. To gain insights into male developmental processes we sought to identify genes transcribe...