Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach

Background and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn’s disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches. Methods: We used, for the fir...

Full description

Saved in:

Bibliographic Details
Published in	Gut Vol. 55; no. 2; pp. 205 - 211
Main Authors	Manichanh, C, Rigottier-Gois, L, Bonnaud, E, Gloux, K, Pelletier, E, Frangeul, L, Nalin, R, Jarrin, C, Chardon, P, Marteau, P, Roca, J, Dore, J
Format	Journal Article
Language	English
Published	London BMJ Publishing Group Ltd and British Society of Gastroenterology 01.02.2006 BMJ BMJ Publishing Group LTD BMJ Publishing Group BMJ Group
Subjects	Adolescent Adult Bacteria Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Bacterial Typing Techniques Biological and medical sciences Cloning CPL Crohn Disease - microbiology Crohn patient library Crohn's disease Deoxyribonucleic acid DNA DNA, Bacterial - genetics Ecosystem Ecosystems faecal microbiota Feces - microbiology Female Firmicutes FISH fluorescent in situ hybridisation Gastroenterology. Liver. Pancreas. Abdomen Gene Library Genes Genomes healthy subject library HSL Humans IBD In Situ Hybridization, Fluorescence Inflammatory Bowel Disease Life Sciences Male Medical sciences metagenome Microorganisms Molecular weight operational taxonomic unit Other diseases. Semiology OTU PCR Phylogenetics Phylogeny polymerase chain reaction RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics saline sodium citrate SDS sodium dodecyl sulphate SSC Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies Crohn disease Gastroenterology Digestive diseases Intestinal disease Surgical approach Feces Inflammatory disease PHYLOGENY 16S rRNA CROHN'S DISEASE FAECAL MICROBIOTA METAGENOME FIRMICUTES FLUORESCENT IN SITU HIBRIDIZATION
Online Access	Get full text

Cover

Loading…

Abstract	Background and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn’s disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches. Methods: We used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We used a fosmid vector to construct two libraries of genomic DNA isolated directly from faecal samples of six healthy donors and six patients with CD. Bacterial diversity was analysed by screening the two DNA libraries, each composed of 25 000 clones, for the 16S rRNA gene by DNA hybridisation. Results: Among 1190 selected clones, we identified 125 non-redundant ribotypes mainly represented by the phyla Bacteroidetes and Firmicutes. Among the Firmicutes, 43 distinct ribotypes were identified in the healthy microbiota, compared with only 13 in CD (p<0.025). Fluorescent in situ hybridisation directly targeting 16S rRNA in faecal samples analysed individually (n = 12) confirmed the significant reduction in the proportion of bacteria belonging to this phylum in CD patients (p<0.02). Conclusion: The metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species.
AbstractList	Background and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn’s disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches. Methods: We used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We used a fosmid vector to construct two libraries of genomic DNA isolated directly from faecal samples of six healthy donors and six patients with CD. Bacterial diversity was analysed by screening the two DNA libraries, each composed of 25 000 clones, for the 16S rRNA gene by DNA hybridisation. Results: Among 1190 selected clones, we identified 125 non-redundant ribotypes mainly represented by the phyla Bacteroidetes and Firmicutes. Among the Firmicutes, 43 distinct ribotypes were identified in the healthy microbiota, compared with only 13 in CD (p<0.025). Fluorescent in situ hybridisation directly targeting 16S rRNA in faecal samples analysed individually (n = 12) confirmed the significant reduction in the proportion of bacteria belonging to this phylum in CD patients (p<0.02). Conclusion: The metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species. A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches. We used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We used a fosmid vector to construct two libraries of genomic DNA isolated directly from faecal samples of six healthy donors and six patients with CD. Bacterial diversity was analysed by screening the two DNA libraries, each composed of 25,000 clones, for the 16S rRNA gene by DNA hybridisation. Among 1190 selected clones, we identified 125 non-redundant ribotypes mainly represented by the phyla Bacteroidetes and Firmicutes. Among the Firmicutes, 43 distinct ribotypes were identified in the healthy microbiota, compared with only 13 in CD (p<0.025). Fluorescent in situ hybridisation directly targeting 16S rRNA in faecal samples analysed individually (n=12) confirmed the significant reduction in the proportion of bacteria belonging to this phylum in CD patients (p<0.02). The metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species. A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches.BACKGROUND AND AIMA role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of such a complex ecosystem is difficult, even with culture independent molecular approaches.We used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We used a fosmid vector to construct two libraries of genomic DNA isolated directly from faecal samples of six healthy donors and six patients with CD. Bacterial diversity was analysed by screening the two DNA libraries, each composed of 25,000 clones, for the 16S rRNA gene by DNA hybridisation.METHODSWe used, for the first time, a comprehensive metagenomic approach to investigate the full range of intestinal microbial diversity. We used a fosmid vector to construct two libraries of genomic DNA isolated directly from faecal samples of six healthy donors and six patients with CD. Bacterial diversity was analysed by screening the two DNA libraries, each composed of 25,000 clones, for the 16S rRNA gene by DNA hybridisation.Among 1190 selected clones, we identified 125 non-redundant ribotypes mainly represented by the phyla Bacteroidetes and Firmicutes. Among the Firmicutes, 43 distinct ribotypes were identified in the healthy microbiota, compared with only 13 in CD (p<0.025). Fluorescent in situ hybridisation directly targeting 16S rRNA in faecal samples analysed individually (n=12) confirmed the significant reduction in the proportion of bacteria belonging to this phylum in CD patients (p<0.02).RESULTSAmong 1190 selected clones, we identified 125 non-redundant ribotypes mainly represented by the phyla Bacteroidetes and Firmicutes. Among the Firmicutes, 43 distinct ribotypes were identified in the healthy microbiota, compared with only 13 in CD (p<0.025). Fluorescent in situ hybridisation directly targeting 16S rRNA in faecal samples analysed individually (n=12) confirmed the significant reduction in the proportion of bacteria belonging to this phylum in CD patients (p<0.02).The metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species.CONCLUSIONThe metagenomic approach allowed us to detect a reduced complexity of the bacterial phylum Firmicutes as a signature of the faecal microbiota in patients with CD. It also indicated the presence of new bacterial species.
Author	Bonnaud, E Frangeul, L Jarrin, C Rigottier-Gois, L Roca, J Gloux, K Pelletier, E Nalin, R Marteau, P Chardon, P Dore, J Manichanh, C
AuthorAffiliation	R Nalin , C Jarrin , LibraGen, Bat Canal Biotech I, Toulouse, France P Marteau , Gastroenterology Department, European Hospital Georges Pompidou, Paris, France L Frangeul , Genopole, Institut Pasteur, Paris, France C Manichanh , L Rigottier‐Gois , E Bonnaud , K Gloux , J Dore , Unité d'Ecologie et de Physiologie du système Digestif, INRA Jouy‐en‐Josas, France P Chardon , UMR INRA CEA radiobiologie et étude du génome, INRA Domaine de Vilvert, Jouy‐en‐Josas, Cedex France J Roca , Department of Molecular Biology, IBMB‐CSIC, Barcelona, Spain E Pelletier , Genoscope, Centre National de Séquençage, Evry cedex, France
AuthorAffiliation_xml	– name: P Chardon , UMR INRA CEA radiobiologie et étude du génome, INRA Domaine de Vilvert, Jouy‐en‐Josas, Cedex France – name: E Pelletier , Genoscope, Centre National de Séquençage, Evry cedex, France – name: L Frangeul , Genopole, Institut Pasteur, Paris, France – name: P Marteau , Gastroenterology Department, European Hospital Georges Pompidou, Paris, France – name: R Nalin , C Jarrin , LibraGen, Bat Canal Biotech I, Toulouse, France – name: C Manichanh , L Rigottier‐Gois , E Bonnaud , K Gloux , J Dore , Unité d'Ecologie et de Physiologie du système Digestif, INRA Jouy‐en‐Josas, France – name: J Roca , Department of Molecular Biology, IBMB‐CSIC, Barcelona, Spain
Author_xml	– sequence: 1 givenname: C surname: Manichanh fullname: Manichanh, C organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 2 givenname: L surname: Rigottier-Gois fullname: Rigottier-Gois, L organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 3 givenname: E surname: Bonnaud fullname: Bonnaud, E organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 4 givenname: K surname: Gloux fullname: Gloux, K organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 5 givenname: E surname: Pelletier fullname: Pelletier, E organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 6 givenname: L surname: Frangeul fullname: Frangeul, L organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 7 givenname: R surname: Nalin fullname: Nalin, R organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 8 givenname: C surname: Jarrin fullname: Jarrin, C organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 9 givenname: P surname: Chardon fullname: Chardon, P organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 10 givenname: P surname: Marteau fullname: Marteau, P organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 11 givenname: J surname: Roca fullname: Roca, J organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain – sequence: 12 givenname: J surname: Dore fullname: Dore, J organization: Department of Molecular Biology, IBMB-CSIC, Barcelona, Spain
BackLink	http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17402321$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/16188921$$D View this record in MEDLINE/PubMed https://hal.inrae.fr/hal-02667954$$DView record in HAL
BookMark	eNqFksuO0zAUhi00iJkprNmhSAgkkNKx4_iSDdKoXAZUQEIwSyzbtVuXJC52UtEdr8Hr8SQ4pMxAF8zGtuzvP-f3OecUHLW-NQDcR3CKEKZny76bFhCSKWSYI3YLnKCS8hwXnB-BEwgRywkrq2NwGuMaQsh5he6AY0RROhXoBHz-YBa9Nots4bYmRNftMm8zK42WddY4HbxyvpOZa7NZ8Kv25_cfMbHRyGiyYLZG1kmsdpnMGtPJpWl9UmVyswle6tVdcNvKOpp7-30CPr188XF2kc_fv3o9O5_ninDW5aSSEmMKpVWwRFDrUmOIFLOcopJDxagsrKowU1RJarS1FnKkqaYGF4poPAHPxribXjVmoU3bBVmLTXCNDDvhpRP_vrRuJZZ-KxAnlECYAjwZA6wOZBfnczHcwYJSVpFyixL7eJ8s-K-9iZ1oXNSmrmVrfB8Fg5QXFaI3gqgqMSZpmYCHB-Da96FNFROIsSpBGA8eH_z9ySubf7qZgEd7QMbUPxtkq1285lgJC_ybOxu51N4Yg7HXCBTDXIk0V2KYKzHOVVKQA4V2neycH6rp6v_o8lHnYme-XaWR4YugDDMi3l3OxFuCn7PZm0sxOHs68qpZ32jqF0qN7jA
CODEN	GUTTAK
CitedBy_id	crossref_primary_10_14309_ctg_0000000000000009 crossref_primary_10_1002_mnfr_202300376 crossref_primary_10_1097_MIB_0000000000000908 crossref_primary_10_3390_ijms252313194 crossref_primary_10_3390_app13031742 crossref_primary_10_1016_j_anifeedsci_2020_114672 crossref_primary_10_1002_ibd_21436 crossref_primary_10_1016_j_jprot_2019_103436 crossref_primary_10_1002_ibd_20101 crossref_primary_10_1093_toxsci_kfu128 crossref_primary_10_1139_h11_101 crossref_primary_10_1128_mBio_01012_14 crossref_primary_10_1016_j_disamonth_2023_101606 crossref_primary_10_1080_19490976_2021_1882928 crossref_primary_10_1111_febs_16245 crossref_primary_10_3389_fmicb_2020_00393 crossref_primary_10_1093_femsre_fuaa060 crossref_primary_10_1586_erm_09_16 crossref_primary_10_1007_s00203_019_01787_w crossref_primary_10_3389_fmicb_2020_01256 crossref_primary_10_1016_j_bj_2023_01_004 crossref_primary_10_1152_ajpgi_00048_2015 crossref_primary_10_1016_j_envint_2019_105187 crossref_primary_10_1097_QCO_0b013e3282a56a99 crossref_primary_10_3109_00365521_2015_1105286 crossref_primary_10_1016_j_mam_2011_10_014 crossref_primary_10_1021_pr8009885 crossref_primary_10_3748_wjg_14_390 crossref_primary_10_1002_ibd_20548 crossref_primary_10_3390_ijms22041623 crossref_primary_10_1007_s13555_023_00904_4 crossref_primary_10_3168_jds_2012_5426 crossref_primary_10_1017_S0007114510003363 crossref_primary_10_1016_j_phrs_2012_09_008 crossref_primary_10_1111_apt_14384 crossref_primary_10_1016_j_lwt_2020_109876 crossref_primary_10_1055_a_1736_2627 crossref_primary_10_1080_10408398_2016_1274877 crossref_primary_10_1016_S0399_8320_09_73148_3 crossref_primary_10_3390_nu13030881 crossref_primary_10_1111_jfd_12799 crossref_primary_10_1039_C7DT04103A crossref_primary_10_3390_ijms222313156 crossref_primary_10_1126_sciadv_1500997 crossref_primary_10_1002_ibd_20547 crossref_primary_10_1093_ibd_izae307 crossref_primary_10_1002_ibd_21874 crossref_primary_10_1111_apt_14324 crossref_primary_10_3389_fmicb_2021_742033 crossref_primary_10_1097_01_mib_0000235828_09305_0c crossref_primary_10_4161_viru_27864 crossref_primary_10_1053_j_gastro_2007_05_030 crossref_primary_10_1126_science_aac4812 crossref_primary_10_1016_j_ygyno_2015_04_036 crossref_primary_10_1111_ijfs_16280 crossref_primary_10_1080_14712598_2019_1673725 crossref_primary_10_1016_j_critrevonc_2018_03_025 crossref_primary_10_1038_s41579_025_01163_0 crossref_primary_10_1017_S0029665114000597 crossref_primary_10_1136_gutjnl_2014_307198 crossref_primary_10_1371_journal_pone_0248427 crossref_primary_10_1016_j_ajog_2019_04_029 crossref_primary_10_4292_wjgpt_v7_i1_112 crossref_primary_10_3389_fimmu_2023_1284133 crossref_primary_10_3748_wjg_v21_i3_803 crossref_primary_10_1016_j_mgene_2020_100713 crossref_primary_10_1111_exd_14420 crossref_primary_10_1186_s13099_018_0276_3 crossref_primary_10_3748_wjg_v24_i13_1464 crossref_primary_10_1371_journal_pone_0184719 crossref_primary_10_3389_fmicb_2023_989303 crossref_primary_10_1016_S1875_5364_15_60002_4 crossref_primary_10_1038_s41467_021_22306_w crossref_primary_10_3389_fmed_2021_669913 crossref_primary_10_1038_mi_2014_128 crossref_primary_10_3390_nu12113433 crossref_primary_10_1080_10408398_2014_941457 crossref_primary_10_1371_journal_pone_0063157 crossref_primary_10_1128_AEM_02204_06 crossref_primary_10_1177_1756283X12454590 crossref_primary_10_1146_annurev_immunol_030409_101225 crossref_primary_10_1186_s40168_022_01331_x crossref_primary_10_1093_bib_bbz034 crossref_primary_10_5713_ab_21_0318 crossref_primary_10_1016_j_immuni_2014_05_016 crossref_primary_10_1016_j_jinf_2022_01_005 crossref_primary_10_1371_journal_pone_0219489 crossref_primary_10_1016_j_immuni_2014_05_014 crossref_primary_10_1093_bioinformatics_btad747 crossref_primary_10_1016_j_mimet_2008_07_025 crossref_primary_10_3402_jom_v4i0_9367 crossref_primary_10_3920_BM2015_0114 crossref_primary_10_1016_j_immuni_2014_05_013 crossref_primary_10_3390_cancers13071748 crossref_primary_10_1016_j_jff_2018_05_041 crossref_primary_10_1016_j_ijbiomac_2024_136687 crossref_primary_10_1126_science_1213799 crossref_primary_10_1016_j_tibtech_2011_06_011 crossref_primary_10_1186_s12866_025_03812_z crossref_primary_10_1016_j_bcp_2011_07_088 crossref_primary_10_1093_cdn_nzac110 crossref_primary_10_1371_journal_pone_0055555 crossref_primary_10_1097_MCG_0b013e31825ca21a crossref_primary_10_1016_j_ypmed_2014_05_010 crossref_primary_10_1182_blood_2020006375 crossref_primary_10_1016_j_mimet_2017_11_014 crossref_primary_10_3390_microorganisms11112616 crossref_primary_10_1038_nrmicro2047 crossref_primary_10_1053_j_gastro_2020_09_036 crossref_primary_10_1073_pnas_1415174111 crossref_primary_10_1016_j_ijbiomac_2025_142392 crossref_primary_10_1002_bies_201300073 crossref_primary_10_1093_ibd_izz188 crossref_primary_10_1155_2014_351204 crossref_primary_10_3389_fimmu_2016_00290 crossref_primary_10_1016_j_jcmgh_2016_07_001 crossref_primary_10_1016_j_vas_2020_100102 crossref_primary_10_1016_j_dld_2020_03_007 crossref_primary_10_1007_s00284_020_02299_3 crossref_primary_10_4166_kjg_2010_55_1_4 crossref_primary_10_1016_j_theriogenology_2017_12_028 crossref_primary_10_1016_j_dib_2019_104948 crossref_primary_10_1016_j_rhum_2013_02_002 crossref_primary_10_1016_S0399_8320_10_70004_X crossref_primary_10_1017_S0029665114001426 crossref_primary_10_1186_s13099_019_0297_6 crossref_primary_10_1038_s41598_021_96289_5 crossref_primary_10_1080_14728222_2017_1363184 crossref_primary_10_2217_bmm_2018_0074 crossref_primary_10_1016_j_cgh_2015_02_043 crossref_primary_10_1016_j_xcrm_2023_101124 crossref_primary_10_1016_j_jaut_2016_06_009 crossref_primary_10_3390_molecules25235681 crossref_primary_10_1007_s12011_019_01877_2 crossref_primary_10_1093_ecco_jcc_jjv203 crossref_primary_10_1016_j_jnutbio_2018_04_004 crossref_primary_10_1161_CIRCULATIONAHA_115_019645 crossref_primary_10_1051_medsci_20143003013 crossref_primary_10_1097_MD_0000000000015718 crossref_primary_10_1038_ncomms4889 crossref_primary_10_1186_s13567_018_0538_6 crossref_primary_10_1016_j_dld_2020_10_033 crossref_primary_10_3389_fmicb_2022_958346 crossref_primary_10_1007_s11938_019_00221_w crossref_primary_10_1016_j_jff_2024_106321 crossref_primary_10_1155_2008_597603 crossref_primary_10_1186_s12989_020_00349_z crossref_primary_10_1186_2049_2618_1_15 crossref_primary_10_1038_ajg_2011_58 crossref_primary_10_1039_D1FO02702F crossref_primary_10_1051_medsci_2024101 crossref_primary_10_1016_j_imbio_2014_11_014 crossref_primary_10_1016_j_anifeedsci_2020_114617 crossref_primary_10_1097_MIB_0000000000000011 crossref_primary_10_4103_sjg_SJG_580_19 crossref_primary_10_1016_j_crfs_2023_100521 crossref_primary_10_3390_nu13093143 crossref_primary_10_1038_s41564_024_01896_3 crossref_primary_10_3109_1040841X_2011_638273 crossref_primary_10_1067_j_cpsurg_2016_06_001 crossref_primary_10_1111_imm_13150 crossref_primary_10_1093_femsre_fuaa020 crossref_primary_10_1111_j_1472_765X_2008_02444_x crossref_primary_10_1111_j_1574_695X_2007_00337_x crossref_primary_10_1186_2049_2618_1_26 crossref_primary_10_1155_2017_8201672 crossref_primary_10_3389_fimmu_2015_00489 crossref_primary_10_1038_srep45308 crossref_primary_10_1038_ismej_2008_37 crossref_primary_10_1159_000356454 crossref_primary_10_1016_j_jcmgh_2020_03_008 crossref_primary_10_1097_MOG_0b013e3282eeb43b crossref_primary_10_1155_2014_152428 crossref_primary_10_1002_ibd_20903 crossref_primary_10_1038_s41540_018_0063_2 crossref_primary_10_3390_molecules27196461 crossref_primary_10_1080_00365520802433231 crossref_primary_10_1097_MIB_0000000000000036 crossref_primary_10_1007_s00253_021_11333_8 crossref_primary_10_3390_nu14163384 crossref_primary_10_1177_1099800415620840 crossref_primary_10_3389_fimmu_2017_00598 crossref_primary_10_1007_s00203_010_0568_6 crossref_primary_10_1007_s13365_015_0357_8 crossref_primary_10_1097_HNP_0000000000000213 crossref_primary_10_1586_17474124_2_3_337 crossref_primary_10_1016_j_jaci_2015_03_036 crossref_primary_10_3390_nu11040923 crossref_primary_10_1016_j_febslet_2014_03_019 crossref_primary_10_1007_s10620_012_2236_y crossref_primary_10_1086_510385 crossref_primary_10_3389_fimmu_2020_02144 crossref_primary_10_3390_microorganisms9040697 crossref_primary_10_1038_ajg_2014_73 crossref_primary_10_1371_journal_pone_0084960 crossref_primary_10_2217_fon_2021_0087 crossref_primary_10_1016_j_crvi_2016_04_008 crossref_primary_10_2217_ahe_11_8 crossref_primary_10_1111_j_1574_6941_2008_00556_x crossref_primary_10_1155_2008_175285 crossref_primary_10_1097_MIB_0000000000000461 crossref_primary_10_1016_j_jiac_2019_02_008 crossref_primary_10_1128_JCM_01542_06 crossref_primary_10_3389_fphys_2017_01064 crossref_primary_10_1097_MOG_0000000000000216 crossref_primary_10_1371_journal_pone_0160353 crossref_primary_10_4061_2010_671258 crossref_primary_10_1038_s41598_021_86425_6 crossref_primary_10_3390_nu7010045 crossref_primary_10_1016_j_gecco_2024_e02983 crossref_primary_10_1097_MIB_0000000000000454 crossref_primary_10_3390_immuno1040040 crossref_primary_10_3390_ijms241713504 crossref_primary_10_1186_s12864_022_08423_w crossref_primary_10_1039_D3FO03612J crossref_primary_10_1136_flgastro_2011_100097 crossref_primary_10_3389_fcimb_2018_00025 crossref_primary_10_1007_s40200_020_00511_6 crossref_primary_10_3389_fped_2019_00326 crossref_primary_10_1111_j_1574_6968_2009_01514_x crossref_primary_10_3389_fmicb_2017_01809 crossref_primary_10_1111_1751_2980_12591 crossref_primary_10_1016_j_autrev_2019_03_006 crossref_primary_10_1097_MIB_0000000000000488 crossref_primary_10_1016_j_idairyj_2019_04_014 crossref_primary_10_1016_j_jaip_2021_05_045 crossref_primary_10_1186_s12866_024_03570_4 crossref_primary_10_1186_s12917_017_1073_9 crossref_primary_10_1002_med_21584 crossref_primary_10_1097_MCG_0000000000001170 crossref_primary_10_1016_j_autrev_2019_03_016 crossref_primary_10_7717_peerj_12977 crossref_primary_10_1186_s12974_020_1705_z crossref_primary_10_1007_s00018_012_0993_6 crossref_primary_10_1186_1471_230X_9_95 crossref_primary_10_23736_S2724_5985_21_02907_7 crossref_primary_10_1016_j_foodres_2023_113797 crossref_primary_10_5217_ir_2018_16_2_209 crossref_primary_10_1089_ees_2014_0518 crossref_primary_10_1152_ajpgi_00382_2007 crossref_primary_10_1016_j_foodres_2021_110676 crossref_primary_10_1016_j_cgh_2015_02_028 crossref_primary_10_1155_2012_157948 crossref_primary_10_1111_nyas_12468 crossref_primary_10_1007_s12275_021_0632_8 crossref_primary_10_1017_S0954422416000019 crossref_primary_10_1152_ajpgi_00319_2017 crossref_primary_10_3748_wjg_14_845 crossref_primary_10_3389_fcimb_2023_1191126 crossref_primary_10_1007_s12263_011_0226_x crossref_primary_10_1155_2019_1092563 crossref_primary_10_1016_j_chom_2008_05_001 crossref_primary_10_3390_nu7010017 crossref_primary_10_1038_s41598_018_30055_y crossref_primary_10_1186_1471_2164_15_202 crossref_primary_10_1007_s10620_020_06715_3 crossref_primary_10_1146_annurev_micro_090110_102922 crossref_primary_10_2147_JIR_S353038 crossref_primary_10_1186_s40104_019_0401_2 crossref_primary_10_5468_ogs_21185 crossref_primary_10_18632_oncotarget_6463 crossref_primary_10_1016_j_celrep_2017_06_060 crossref_primary_10_1016_j_chom_2008_05_010 crossref_primary_10_1186_s40168_017_0262_x crossref_primary_10_1007_s10620_018_5428_2 crossref_primary_10_1038_nrmicro3451 crossref_primary_10_1038_s41385_020_0296_4 crossref_primary_10_3389_fmicb_2017_00525 crossref_primary_10_1186_s12931_020_01340_0 crossref_primary_10_2217_imt_13_130 crossref_primary_10_1016_j_ab_2013_08_021 crossref_primary_10_1016_S1773_035X_15_72819_4 crossref_primary_10_1111_j_1365_2036_2009_04072_x crossref_primary_10_1053_j_gastro_2009_01_072 crossref_primary_10_1016_j_nmni_2025_101567 crossref_primary_10_1016_S0399_8320_10_70017_8 crossref_primary_10_1186_s40168_024_01832_x crossref_primary_10_3390_metabo12010044 crossref_primary_10_1038_nature11553 crossref_primary_10_3389_fmicb_2018_02247 crossref_primary_10_1016_j_molmed_2016_01_002 crossref_primary_10_1073_pnas_0804812105 crossref_primary_10_1093_ibd_izy281 crossref_primary_10_3390_biomedicines12010158 crossref_primary_10_1093_ibd_izz130 crossref_primary_10_1002_advs_201900752 crossref_primary_10_3390_nu7125497 crossref_primary_10_1128_mBio_01212_14 crossref_primary_10_1186_1471_230X_13_20 crossref_primary_10_3168_jds_2017_14139 crossref_primary_10_1111_j_1365_2567_2012_03624_x crossref_primary_10_1016_j_bcp_2011_09_004 crossref_primary_10_1099_jmm_0_021170_0 crossref_primary_10_1080_10790268_2020_1769949 crossref_primary_10_1042_BST0391067 crossref_primary_10_1111_j_1751_2980_2010_00449_x crossref_primary_10_1186_s13099_024_00657_1 crossref_primary_10_3389_fimmu_2022_928865 crossref_primary_10_1016_j_resmic_2007_12_011 crossref_primary_10_1016_j_bbrc_2019_01_123 crossref_primary_10_1016_j_aquaculture_2024_741741 crossref_primary_10_3390_ijms232113328 crossref_primary_10_1517_14712598_2014_880420 crossref_primary_10_1007_s13167_024_00351_x crossref_primary_10_12938_bmfh_31_71 crossref_primary_10_3389_fmicb_2023_1034325 crossref_primary_10_1002_ibd_20174 crossref_primary_10_3389_fped_2020_620254 crossref_primary_10_1111_j_1749_6632_2009_04036_x crossref_primary_10_1002_ibd_21026 crossref_primary_10_1016_j_sjbs_2019_09_004 crossref_primary_10_1021_acsnano_7b08660 crossref_primary_10_1002_mnfr_201800535 crossref_primary_10_1016_j_biopha_2022_113079 crossref_primary_10_3748_wjg_v21_i40_11236 crossref_primary_10_1093_ecco_jcc_jjaa081 crossref_primary_10_1186_s40779_022_00373_4 crossref_primary_10_1016_j_diagmicrobio_2012_11_022 crossref_primary_10_1016_S2468_1253_16_30241_2 crossref_primary_10_1038_s41598_021_86247_6 crossref_primary_10_1371_journal_pone_0021644 crossref_primary_10_3390_ijms24065767 crossref_primary_10_1111_j_1600_065X_2011_01079_x crossref_primary_10_1016_j_mam_2025_101349 crossref_primary_10_1146_annurev_ecolsys_110411_160307 crossref_primary_10_1099_jmm_0_000331 crossref_primary_10_3390_pathogens10121550 crossref_primary_10_1111_1751_7915_13583 crossref_primary_10_1002_ibd_20151 crossref_primary_10_1093_ecco_jcc_jjaa094 crossref_primary_10_3389_fcimb_2023_1275405 crossref_primary_10_2147_CEG_S371965 crossref_primary_10_1016_j_celrep_2017_04_006 crossref_primary_10_1097_MIB_0000000000000875 crossref_primary_10_4061_2010_386956 crossref_primary_10_1186_s40168_018_0439_y crossref_primary_10_1080_19490976_2024_2409207 crossref_primary_10_1038_nrmicro2989 crossref_primary_10_1038_s43705_021_00033_z crossref_primary_10_1051_fopen_2018007 crossref_primary_10_1038_scibx_2013_52 crossref_primary_10_1146_annurev_immunol_020711_074937 crossref_primary_10_18632_oncotarget_14758 crossref_primary_10_3390_ijms20020283 crossref_primary_10_1016_j_bbrc_2024_150831 crossref_primary_10_1096_fj_202402572R crossref_primary_10_1111_cei_13276 crossref_primary_10_3389_fimmu_2022_1015372 crossref_primary_10_1038_ismej_2013_80 crossref_primary_10_1080_00365521_2020_1839961 crossref_primary_10_1093_bib_bbs022 crossref_primary_10_5223_pghn_2013_16_1_17 crossref_primary_10_4110_in_2017_17_1_25 crossref_primary_10_1002_wsbm_48 crossref_primary_10_1002_ibd_21460 crossref_primary_10_12677_ACM_2022_1281040 crossref_primary_10_1038_s41598_018_26423_3 crossref_primary_10_3390_life12070972 crossref_primary_10_1146_annurev_publhealth_032013_182426 crossref_primary_10_1007_s10620_013_2844_1 crossref_primary_10_3390_ijms232113358 crossref_primary_10_1038_s41385_019_0252_3 crossref_primary_10_1093_advances_nmac029 crossref_primary_10_1080_00365521_2017_1347812 crossref_primary_10_3168_jds_2011_4384 crossref_primary_10_1016_j_bbadis_2014_05_023 crossref_primary_10_1177_1756283X13482996 crossref_primary_10_1186_s13073_016_0262_7 crossref_primary_10_1155_2019_2624941 crossref_primary_10_1111_j_1572_0241_2007_01592_x crossref_primary_10_4161_gmic_25275 crossref_primary_10_7762_cnr_2021_10_3_181 crossref_primary_10_3390_ijms23115891 crossref_primary_10_1089_zeb_2018_1648 crossref_primary_10_1016_j_jaut_2017_03_009 crossref_primary_10_1111_ijfs_15005 crossref_primary_10_1007_s11154_020_09589_y crossref_primary_10_1097_MD_0000000000005019 crossref_primary_10_1128_mBio_00376_12 crossref_primary_10_3389_fnut_2024_1324793 crossref_primary_10_1371_journal_pone_0109798 crossref_primary_10_1038_nrgastro_2011_3 crossref_primary_10_1093_femsre_fuab011 crossref_primary_10_1097_00054725_200810001_00018 crossref_primary_10_1093_nar_gkn496 crossref_primary_10_1016_j_csbj_2023_11_027 crossref_primary_10_1186_1471_230X_13_131 crossref_primary_10_1111_ped_15677 crossref_primary_10_1152_ajpgi_00044_2014 crossref_primary_10_1002_ibd_21556 crossref_primary_10_1016_S0399_8320_10_70001_4 crossref_primary_10_1128_mBio_00145_21 crossref_primary_10_1016_j_gastrohep_2020_06_025 crossref_primary_10_1146_annurev_immunol_030409_101330 crossref_primary_10_1007_s10096_013_2044_0 crossref_primary_10_1016_S0399_8320_09_73158_6 crossref_primary_10_1128_AEM_01843_08 crossref_primary_10_14218_ERHM_2017_00026 crossref_primary_10_1155_2022_2939921 crossref_primary_10_1128_IAI_00647_12 crossref_primary_10_1128_mSystems_00188_16 crossref_primary_10_3390_diagnostics11061090 crossref_primary_10_1016_j_ijmm_2016_02_010 crossref_primary_10_1186_1757_4749_6_22 crossref_primary_10_1111_cen3_12401 crossref_primary_10_1016_j_jid_2024_07_020 crossref_primary_10_1186_1741_7007_11_61 crossref_primary_10_1038_srep34337 crossref_primary_10_3390_ijms23010206 crossref_primary_10_4161_gmic_24372 crossref_primary_10_3389_fped_2016_00010 crossref_primary_10_1093_ecco_jcc_jjae041 crossref_primary_10_1016_j_nut_2021_111439 crossref_primary_10_3390_ijms222212506 crossref_primary_10_1002_ibd_22860 crossref_primary_10_5009_gnl14344 crossref_primary_10_1073_pnas_1000066107 crossref_primary_10_1371_journal_pone_0218096 crossref_primary_10_1016_j_abb_2025_110294 crossref_primary_10_3748_wjg_v23_i25_4624 crossref_primary_10_3390_nu7021301 crossref_primary_10_3389_fcimb_2019_00002 crossref_primary_10_1371_journal_pone_0034939 crossref_primary_10_1186_1471_2164_15_918 crossref_primary_10_1016_j_jff_2020_104167 crossref_primary_10_5217_ir_2018_00089 crossref_primary_10_1016_j_cels_2020_05_006 crossref_primary_10_3389_fmicb_2015_01050 crossref_primary_10_1007_s11894_006_0037_1 crossref_primary_10_1016_j_mimet_2018_07_003 crossref_primary_10_1016_j_apsb_2024_02_020 crossref_primary_10_1111_j_1365_2249_2010_04139_x crossref_primary_10_1016_j_biotechadv_2012_12_009 crossref_primary_10_1038_s41385_021_00383_w crossref_primary_10_5217_ir_2018_16_1_26 crossref_primary_10_1186_1471_230X_13_175 crossref_primary_10_1038_ismej_2010_92 crossref_primary_10_1016_j_gastrohep_2015_01_004 crossref_primary_10_1080_10408360802485792 crossref_primary_10_1038_s41598_022_07042_5 crossref_primary_10_1038_srep35216 crossref_primary_10_1074_jbc_M113_483628 crossref_primary_10_3390_ijms20051232 crossref_primary_10_1186_s12876_022_02191_3 crossref_primary_10_1016_j_gtc_2017_08_012 crossref_primary_10_1080_19490976_2023_2297872 crossref_primary_10_1186_s12866_018_1154_3 crossref_primary_10_1186_s12864_018_5306_5 crossref_primary_10_1016_j_anaerobe_2017_04_011 crossref_primary_10_1007_s10620_011_1731_x crossref_primary_10_1371_journal_pone_0202587 crossref_primary_10_1111_j_1600_065X_2011_01080_x crossref_primary_10_1155_2018_7192646 crossref_primary_10_1074_jbc_M116_714386 crossref_primary_10_3945_ajcn_112_038893 crossref_primary_10_1128_JCM_01512_08 crossref_primary_10_1002_fsn3_1033 crossref_primary_10_1186_s12931_022_01947_5 crossref_primary_10_1038_s41598_017_13722_4 crossref_primary_10_3389_fphar_2021_644387 crossref_primary_10_1016_j_dci_2016_02_020 crossref_primary_10_3389_fimmu_2014_00318 crossref_primary_10_1016_j_livsci_2020_104120 crossref_primary_10_1007_s12026_013_8413_z crossref_primary_10_1016_j_cll_2014_08_003 crossref_primary_10_1093_rheumatology_keu469 crossref_primary_10_3389_fcell_2021_703310 crossref_primary_10_1016_j_phrs_2016_09_044 crossref_primary_10_1002_jca_21887 crossref_primary_10_2217_fmb_12_37 crossref_primary_10_1093_femsec_fiv054 crossref_primary_10_1007_s00018_013_1318_0 crossref_primary_10_1007_s10620_014_3360_7 crossref_primary_10_1080_17474124_2019_1596025 crossref_primary_10_3389_fmicb_2019_00163 crossref_primary_10_1002_mnfr_201100139 crossref_primary_10_1080_00365521_2016_1216587 crossref_primary_10_1038_s41598_018_22408_4 crossref_primary_10_1111_1462_2920_12934 crossref_primary_10_4161_gmic_22156 crossref_primary_10_1038_nrgastro_2011_133 crossref_primary_10_1016_j_autrev_2021_102845 crossref_primary_10_1136_gutjnl_2015_309333 crossref_primary_10_1164_rccm_201504_0779OC crossref_primary_10_1016_j_neuint_2017_12_003 crossref_primary_10_1016_j_berh_2021_101687 crossref_primary_10_1021_acs_jafc_0c07537 crossref_primary_10_1371_journal_pone_0202929 crossref_primary_10_1016_j_ijpara_2017_11_003 crossref_primary_10_1038_srep04985 crossref_primary_10_1016_j_pharmthera_2014_12_006 crossref_primary_10_1097_CM9_0000000000000351 crossref_primary_10_18632_oncotarget_16458 crossref_primary_10_1159_000510536 crossref_primary_10_1136_gutjnl_2014_307264 crossref_primary_10_3390_ijms15069594 crossref_primary_10_1007_s11894_007_0066_4 crossref_primary_10_3390_medicina59111965 crossref_primary_10_1136_gutjnl_2014_308119 crossref_primary_10_1371_journal_pone_0003578 crossref_primary_10_1016_j_advms_2020_06_003 crossref_primary_10_1007_s11102_021_01137_4 crossref_primary_10_2746_042516409X474284 crossref_primary_10_1038_s41598_022_10450_2 crossref_primary_10_1038_msb_2013_22 crossref_primary_10_1016_j_intimp_2022_108656 crossref_primary_10_1016_j_chom_2012_02_006 crossref_primary_10_1007_s00384_020_03599_7 crossref_primary_10_1007_s11892_013_0409_5 crossref_primary_10_1016_j_jinf_2020_01_023 crossref_primary_10_1038_nutd_2014_18 crossref_primary_10_1002_ibd_21923 crossref_primary_10_1097_MCG_0000000000000351 crossref_primary_10_1152_ajprenal_00298_2018 crossref_primary_10_1371_journal_pone_0115175 crossref_primary_10_1038_s41522_021_00191_x crossref_primary_10_1186_s12884_020_02961_5 crossref_primary_10_1097_MCG_0000000000000356 crossref_primary_10_1136_gutjnl_2016_313235 crossref_primary_10_26442_00403660_2019_04_000211 crossref_primary_10_1002_ibd_20602 crossref_primary_10_3389_fcimb_2023_1278582 crossref_primary_10_1016_j_gtc_2020_08_006 crossref_primary_10_1186_s12929_018_0483_8 crossref_primary_10_1038_s41598_019_49833_3 crossref_primary_10_7243_2052_6180_3_6 crossref_primary_10_7243_2052_6180_3_7 crossref_primary_10_1080_10242420701444314 crossref_primary_10_7243_2052_6180_3_5 crossref_primary_10_1007_s10620_020_06173_x crossref_primary_10_3390_ijms21051711 crossref_primary_10_1016_j_tim_2017_09_011 crossref_primary_10_1016_j_immuni_2009_08_009 crossref_primary_10_1038_srep43211 crossref_primary_10_1136_egastro_2023_100006 crossref_primary_10_26508_lsa_201900592 crossref_primary_10_2174_1389450121666200324151530 crossref_primary_10_1016_S0399_8320_10_70014_2 crossref_primary_10_1097_CM9_0000000000000308 crossref_primary_10_1128_msystems_00188_17 crossref_primary_10_2152_jmi_63_27 crossref_primary_10_6000_1927_5951_2018_08_02_1 crossref_primary_10_1016_j_imlet_2023_02_006 crossref_primary_10_1186_s12967_016_0989_3 crossref_primary_10_1038_ismej_2012_146 crossref_primary_10_1128_CMR_00060_18 crossref_primary_10_1007_s44403_024_00010_z crossref_primary_10_1016_j_lssr_2023_08_006 crossref_primary_10_1080_17474124_2023_2231340 crossref_primary_10_3389_fmicb_2020_579521 crossref_primary_10_1038_s41598_023_32901_0 crossref_primary_10_3389_fmed_2022_915179 crossref_primary_10_3390_nu16152446 crossref_primary_10_1016_j_crfs_2022_08_011 crossref_primary_10_3390_cells11030455 crossref_primary_10_1080_14737159_2016_1184574 crossref_primary_10_5507_bp_2021_042 crossref_primary_10_14309_ctg_0000000000000389 crossref_primary_10_1038_ajg_2010_398 crossref_primary_10_1371_journal_pone_0244341 crossref_primary_10_1111_apt_13302 crossref_primary_10_1016_j_anaerobe_2013_09_011 crossref_primary_10_1134_S1990750820040113 crossref_primary_10_3390_nu16060778 crossref_primary_10_1007_s00103_014_2095_0 crossref_primary_10_4161_gmic_21216 crossref_primary_10_1053_j_gastro_2011_04_011 crossref_primary_10_1089_bio_2019_0112 crossref_primary_10_1007_s12079_022_00695_x crossref_primary_10_3390_ijms23137093 crossref_primary_10_1038_s41385_021_00433_3 crossref_primary_10_1016_j_fbio_2023_103546 crossref_primary_10_1111_j_1462_2920_2009_01982_x crossref_primary_10_1111_j_1462_2920_2007_01503_x crossref_primary_10_1016_j_mrfmmm_2007_03_011 crossref_primary_10_1016_j_nutres_2017_11_008 crossref_primary_10_1021_acs_chemrev_2c00431 crossref_primary_10_3389_fphar_2018_00468 crossref_primary_10_3109_09637486_2015_1025721 crossref_primary_10_3389_fmicb_2018_01008 crossref_primary_10_1038_nrg3182 crossref_primary_10_1177_0884533615609896 crossref_primary_10_1073_pnas_1922189117 crossref_primary_10_1038_s41591_023_02599_8 crossref_primary_10_3390_nu11071541 crossref_primary_10_3748_wjg_v26_i21_2758 crossref_primary_10_1038_s41598_021_88823_2 crossref_primary_10_3390_biomedicines13030708 crossref_primary_10_1111_imr_12185 crossref_primary_10_1016_j_phymed_2021_153914 crossref_primary_10_1109_TCBB_2011_113 crossref_primary_10_3892_etm_2021_10868 crossref_primary_10_1002_jsfa_12732 crossref_primary_10_3748_wjg_v28_i30_4089 crossref_primary_10_1007_s13346_013_0156_9 crossref_primary_10_1371_journal_pone_0114352 crossref_primary_10_1515_BC_2009_052 crossref_primary_10_1002_ajp_22989 crossref_primary_10_1016_S1773_035X_22_00309_4 crossref_primary_10_3389_fimmu_2021_789334 crossref_primary_10_1007_s00253_021_11617_z crossref_primary_10_1186_s12967_019_1810_x crossref_primary_10_3390_ani10122199 crossref_primary_10_1186_1471_2180_9_68 crossref_primary_10_3748_wjg_v22_i40_8929 crossref_primary_10_3389_fmicb_2016_01081 crossref_primary_10_1002_mnfr_201600129 crossref_primary_10_1152_ajpgi_00239_2011 crossref_primary_10_1016_j_biopha_2021_112414 crossref_primary_10_1097_MCO_0000000000000284 crossref_primary_10_1152_ajpgi_00193_2009 crossref_primary_10_4014_jmb_2009_09005 crossref_primary_10_1007_s12275_018_8152_x crossref_primary_10_3389_fimmu_2020_01164 crossref_primary_10_1038_srep15699 crossref_primary_10_1097_MIB_0000000000000129 crossref_primary_10_1264_jsme2_ME16024 crossref_primary_10_1111_1758_2229_13233 crossref_primary_10_2492_inflammregen_35_122 crossref_primary_10_3389_fmicb_2022_856165 crossref_primary_10_1155_2008_639803 crossref_primary_10_1016_j_biopha_2023_115202 crossref_primary_10_3390_gidisord1010007 crossref_primary_10_3389_fmicb_2015_01543 crossref_primary_10_1016_j_celrep_2022_111809 crossref_primary_10_2217_fmb_10_126 crossref_primary_10_1016_j_gtc_2020_10_008 crossref_primary_10_1038_nrmicro3552 crossref_primary_10_3748_wjg_v22_i42_9257 crossref_primary_10_1111_imm_13586 crossref_primary_10_18632_oncotarget_20477 crossref_primary_10_1016_j_foodchem_2022_134989 crossref_primary_10_1080_21678421_2021_1904994 crossref_primary_10_1186_s40168_018_0460_1 crossref_primary_10_1183_13993003_02086_2016 crossref_primary_10_2174_1570159X19666210629145351 crossref_primary_10_1186_s40168_018_0603_4 crossref_primary_10_1016_j_gastre_2020_06_016 crossref_primary_10_1186_1752_0509_8_41 crossref_primary_10_4161_gmic_19320 crossref_primary_10_1038_nature11450 crossref_primary_10_1016_j_gastrohep_2010_11_009 crossref_primary_10_1016_j_immuni_2012_04_011 crossref_primary_10_1038_srep43741 crossref_primary_10_1097_MEG_0000000000001330 crossref_primary_10_1371_journal_pone_0095534 crossref_primary_10_1186_s13059_021_02306_1 crossref_primary_10_4103_sjg_sjg_368_22 crossref_primary_10_31665_JFB_2019_5175 crossref_primary_10_1016_j_fct_2014_06_024 crossref_primary_10_1016_j_retram_2019_01_002 crossref_primary_10_1002_advs_201900610 crossref_primary_10_18097_pbmc20206603233 crossref_primary_10_1371_journal_pone_0199640 crossref_primary_10_1111_1751_7915_12752 crossref_primary_10_1053_j_gastro_2015_04_017 crossref_primary_10_1093_dnares_dst037 crossref_primary_10_1016_j_ebiom_2019_09_008 crossref_primary_10_7717_peerj_14842 crossref_primary_10_1111_jhn_12371 crossref_primary_10_3389_fnins_2019_01295 crossref_primary_10_1136_gutjnl_2016_313678 crossref_primary_10_1186_s13073_022_01099_7 crossref_primary_10_1111_apt_12976 crossref_primary_10_5217_ir_2014_12_3_178 crossref_primary_10_1002_ibd_21177 crossref_primary_10_1016_j_amjmed_2018_03_010 crossref_primary_10_1007_s10096_012_1641_7 crossref_primary_10_3389_fmed_2024_1395861 crossref_primary_10_1093_dnares_dst006 crossref_primary_10_1007_s11033_020_05318_5 crossref_primary_10_1096_fj_202002697RRR crossref_primary_10_1111_apt_16096 crossref_primary_10_3390_medicina56010038 crossref_primary_10_1007_s11882_013_0382_8 crossref_primary_10_1097_JCMA_0000000000000532 crossref_primary_10_1016_j_ebiom_2019_05_052 crossref_primary_10_4291_wjgp_v11_i3_64 crossref_primary_10_1007_s00248_010_9796_1 crossref_primary_10_1136_gutjnl_2014_307649 crossref_primary_10_1111_1574_6941_12256 crossref_primary_10_3389_fmicb_2023_1188455 crossref_primary_10_1186_s40168_017_0283_5 crossref_primary_10_1053_j_scrs_2014_05_013 crossref_primary_10_3389_fimmu_2020_01192 crossref_primary_10_1128_aem_00915_24 crossref_primary_10_1179_146532806X107403 crossref_primary_10_1373_clinchem_2008_107565 crossref_primary_10_1016_j_bbagen_2014_05_003 crossref_primary_10_1371_journal_pone_0137429 crossref_primary_10_1586_eri_10_14 crossref_primary_10_1080_19490976_2024_2323237 crossref_primary_10_3389_fmicb_2017_00625 crossref_primary_10_3389_fcimb_2020_567268 crossref_primary_10_1016_j_bbi_2012_12_005 crossref_primary_10_1007_s00248_010_9787_2 crossref_primary_10_1097_SLA_0b013e3181e3dc8b crossref_primary_10_1038_s41419_021_03395_3 crossref_primary_10_1111_anu_12320 crossref_primary_10_1111_j_1751_2980_2007_00310_x crossref_primary_10_1007_s11926_018_0758_9 crossref_primary_10_1016_j_cimid_2015_10_005 crossref_primary_10_1080_10408398_2015_1010034 crossref_primary_10_1111_jpn_13088 crossref_primary_10_3390_microorganisms10010167 crossref_primary_10_1177_1756283X16644242 crossref_primary_10_1089_zeb_2012_0814 crossref_primary_10_1039_C9FO01519A crossref_primary_10_1111_j_1572_0241_2008_01868_x crossref_primary_10_1002_ibd_20295 crossref_primary_10_1097_MIB_0000000000000970 crossref_primary_10_1038_nature12331 crossref_primary_10_3389_fimmu_2021_578386 crossref_primary_10_1111_imm_12677 crossref_primary_10_1152_ajpgi_00327_2011 crossref_primary_10_1007_s40484_014_0037_3 crossref_primary_10_1038_s41598_024_72797_y crossref_primary_10_1186_s12934_022_01973_4 crossref_primary_10_1053_j_gastro_2019_11_294 crossref_primary_10_17352_2455_2283_000038 crossref_primary_10_1073_pnas_1100292108 crossref_primary_10_1097_MIB_0000000000000518 crossref_primary_10_1152_ajpheart_00512_2019 crossref_primary_10_1016_j_bcp_2016_03_017 crossref_primary_10_1136_bmjopen_2019_036275 crossref_primary_10_1016_j_jnutbio_2015_10_014 crossref_primary_10_1038_ismej_2014_64 crossref_primary_10_1111_1469_0691_12799 crossref_primary_10_1002_ajhb_24058 crossref_primary_10_1038_cti_2016_91 crossref_primary_10_1080_1744666X_2019_1627876 crossref_primary_10_1016_j_semcancer_2020_06_009 crossref_primary_10_1099_jmm_0_001966 crossref_primary_10_1016_j_jaci_2018_09_025 crossref_primary_10_3390_toxins13020106 crossref_primary_10_1371_journal_pone_0062220 crossref_primary_10_1007_s12263_011_0229_7 crossref_primary_10_1073_pnas_0706625104 crossref_primary_10_1002_ibd_21590 crossref_primary_10_1016_j_syapm_2015_06_008 crossref_primary_10_1177_0884533612439895 crossref_primary_10_1128_CMR_00136_21 crossref_primary_10_3390_biomedicines10092140 crossref_primary_10_1016_j_ijpharm_2020_119648 crossref_primary_10_1099_ijsem_0_000617 crossref_primary_10_1097_00054725_200810001_00043 crossref_primary_10_3389_fbioe_2021_675194 crossref_primary_10_1146_annurev_animal_022114_111112 crossref_primary_10_3390_microorganisms8111715 crossref_primary_10_1002_mnfr_201100630 crossref_primary_10_1016_j_intimp_2025_114193 crossref_primary_10_1111_1751_2980_12603 crossref_primary_10_1111_apt_16465 crossref_primary_10_1002_ibd_21108 crossref_primary_10_1016_j_micpath_2016_01_024 crossref_primary_10_3390_nu12071945 crossref_primary_10_1371_journal_pone_0031976 crossref_primary_10_1016_j_jnutbio_2018_08_005 crossref_primary_10_1007_s13679_019_00351_3 crossref_primary_10_1371_journal_ppat_1003829 crossref_primary_10_1371_journal_pone_0003064 crossref_primary_10_3390_molecules27041351 crossref_primary_10_1053_j_gastro_2021_08_057 crossref_primary_10_2527_jas_2010_3392 crossref_primary_10_3390_antiox11101947 crossref_primary_10_4143_crt_2022_080 crossref_primary_10_1080_17474124_2019_1685874 crossref_primary_10_1093_femsml_uqad032 crossref_primary_10_1038_ismej_2014_30 crossref_primary_10_1371_journal_pone_0016384 crossref_primary_10_1155_2011_971938 crossref_primary_10_1016_j_bpg_2016_02_001 crossref_primary_10_1016_j_jaci_2015_12_1331 crossref_primary_10_1038_s41467_022_31761_y crossref_primary_10_15857_ksep_2022_00479 crossref_primary_10_3390_nu11102270 crossref_primary_10_1016_j_tibtech_2011_01_009 crossref_primary_10_1155_2014_398147 crossref_primary_10_1007_s00281_014_0454_4 crossref_primary_10_1021_acs_jafc_9b01687 crossref_primary_10_1007_s11101_023_09866_z crossref_primary_10_1093_ecco_jcc_jjad204 crossref_primary_10_1007_s10123_022_00243_y crossref_primary_10_1371_journal_pcbi_1002358 crossref_primary_10_1080_19490976_2017_1344809 crossref_primary_10_1038_s41598_023_39491_x crossref_primary_10_1042_BSR20231217 crossref_primary_10_5217_ir_2021_00168 crossref_primary_10_1097_MEG_0000000000001918 crossref_primary_10_1186_s13075_022_02733_w crossref_primary_10_3390_ijerph18073742 crossref_primary_10_3390_ani12172187 crossref_primary_10_1016_j_clinthera_2015_03_009 crossref_primary_10_1016_j_idairyj_2009_11_010 crossref_primary_10_1007_s00253_017_8285_6 crossref_primary_10_1038_s41531_021_00170_1 crossref_primary_10_1101_gr_107987_110 crossref_primary_10_1099_ijs_0_000030 crossref_primary_10_1371_journal_pone_0152044 crossref_primary_10_1146_annurev_food_032818_121303 crossref_primary_10_1186_s13059_017_1323_y crossref_primary_10_1016_j_critrevonc_2020_103165 crossref_primary_10_1128_JCM_01720_06 crossref_primary_10_1016_j_jprot_2019_04_009 crossref_primary_10_1016_j_pnpbp_2021_110259 crossref_primary_10_1097_MOG_0b013e328331b6b4 crossref_primary_10_1038_cti_2016_38 crossref_primary_10_1038_ajg_2013_257 crossref_primary_10_1136_gutjnl_2023_330002 crossref_primary_10_1159_000375303 crossref_primary_10_14309_ctg_0000000000000232 crossref_primary_10_1093_dnares_dsm018 crossref_primary_10_1016_S1876_3553_12_60007_6 crossref_primary_10_1007_s00108_022_01395_9 crossref_primary_10_1038_s41598_018_28448_0 crossref_primary_10_1186_1471_2180_14_112 crossref_primary_10_1111_nmo_12046 crossref_primary_10_1016_j_neuint_2018_08_005 crossref_primary_10_3748_wjg_v20_i33_11505 crossref_primary_10_3390_cells9092104 crossref_primary_10_1099_mic_0_042127_0 crossref_primary_10_1373_clinchem_2018_289728 crossref_primary_10_1371_journal_ppat_0040020 crossref_primary_10_1186_1746_6148_9_140 crossref_primary_10_3402_jom_v1i0_2009 crossref_primary_10_1371_journal_pcbi_1004977 crossref_primary_10_3389_fmed_2022_887044 crossref_primary_10_1016_j_jand_2020_04_024 crossref_primary_10_56373_2008_10_4 crossref_primary_10_7554_eLife_39982 crossref_primary_10_3920_BM2012_0029 crossref_primary_10_1002_pmic_201500183 crossref_primary_10_1002_ibd_20783 crossref_primary_10_1128_AEM_02766_16 crossref_primary_10_1111_j_1462_2920_2009_01941_x crossref_primary_10_1002_pmic_201400329 crossref_primary_10_1111_apt_13236 crossref_primary_10_1038_s41575_019_0261_4 crossref_primary_10_1007_s10620_018_5086_4 crossref_primary_10_1016_j_micinf_2021_104816 crossref_primary_10_3390_cells12222654 crossref_primary_10_1371_journal_pone_0202460 crossref_primary_10_1172_JCI72336 crossref_primary_10_1016_j_jsbmb_2016_11_001 crossref_primary_10_1152_ajpgi_00338_2016 crossref_primary_10_3390_nu13041305 crossref_primary_10_1099_mic_0_082610_0 crossref_primary_10_1172_JCI72330 crossref_primary_10_5223_pghn_2013_16_2_71 crossref_primary_10_1007_s00253_020_10838_y crossref_primary_10_3389_fmicb_2018_01948 crossref_primary_10_1002_ibd_21606 crossref_primary_10_1371_journal_pone_0080702 crossref_primary_10_17116_dokgastro20176319_25 crossref_primary_10_1016_j_fshw_2023_02_026 crossref_primary_10_1111_1751_7915_12049 crossref_primary_10_1111_cea_12666 crossref_primary_10_2174_0115665240286793240306053111 crossref_primary_10_1016_j_jceh_2013_03_225 crossref_primary_10_1128_mBio_01263_15 crossref_primary_10_1152_physrev_00018_2018 crossref_primary_10_1186_s40168_021_01114_w crossref_primary_10_1155_2012_493717 crossref_primary_10_3389_fcimb_2021_724376 crossref_primary_10_3390_ijms24097998 crossref_primary_10_1371_journal_pone_0090981 crossref_primary_10_1186_s13059_015_0639_8 crossref_primary_10_4161_gmic_24220 crossref_primary_10_1128_spectrum_00645_21 crossref_primary_10_1128_MMBR_00014_10 crossref_primary_10_1155_2013_297501 crossref_primary_10_1080_19490976_2020_1778262 crossref_primary_10_3389_fimmu_2014_00427 crossref_primary_10_2217_nnm_2019_0191 crossref_primary_10_1055_s_0043_1771467 crossref_primary_10_1093_gastro_goac011 crossref_primary_10_1016_j_fct_2022_113368 crossref_primary_10_1371_journal_pone_0284709 crossref_primary_10_5812_pedinfect_34558 crossref_primary_10_1038_nbt_3960 crossref_primary_10_1111_j_1365_2036_2008_03796_x crossref_primary_10_1038_s41598_019_47204_6 crossref_primary_10_1292_jvms_20_0190 crossref_primary_10_1016_j_freeradbiomed_2018_05_066 crossref_primary_10_1097_MRM_0000000000000085 crossref_primary_10_1099_ijsem_0_005958 crossref_primary_10_3389_fimmu_2018_02318 crossref_primary_10_1038_s41598_022_23757_x crossref_primary_10_1136_flgastro_2022_102119 crossref_primary_10_1080_13543784_2018_1483333 crossref_primary_10_3390_pathogens8030126 crossref_primary_10_1002_mnfr_200700139 crossref_primary_10_1007_s00394_016_1304_z crossref_primary_10_1016_j_bpg_2013_03_005 crossref_primary_10_1097_MPA_0000000000000355 crossref_primary_10_1186_s40168_016_0218_6 crossref_primary_10_1093_ibd_izy060 crossref_primary_10_1002_cam4_6636 crossref_primary_10_3389_fmicb_2020_01405 crossref_primary_10_1093_ibd_izy067 crossref_primary_10_1097_MCG_0000000000001798 crossref_primary_10_3390_nu15092104 crossref_primary_10_1016_j_jss_2019_04_032 crossref_primary_10_1136_bmjpo_2017_000176 crossref_primary_10_1128_mSystems_00065_17 crossref_primary_10_1128_mSystems_00323_18 crossref_primary_10_1016_j_micres_2014_11_002 crossref_primary_10_1016_S0399_8320_10_70015_4 crossref_primary_10_1016_j_csbj_2015_06_001 crossref_primary_10_1111_1758_2229_12411 crossref_primary_10_1016_j_jaci_2013_05_021 crossref_primary_10_3390_microorganisms10051044 crossref_primary_10_1111_imr_12567 crossref_primary_10_1016_j_carbpol_2021_118830 crossref_primary_10_1007_s10620_015_3797_3 crossref_primary_10_1136_gutjnl_2013_304833 crossref_primary_10_1089_ars_2022_0033 crossref_primary_10_3389_fnins_2019_00839 crossref_primary_10_1016_j_anaerobe_2016_12_001 crossref_primary_10_1097_MD_0000000000000051 crossref_primary_10_1016_j_jprot_2024_105360 crossref_primary_10_1055_a_1954_7864 crossref_primary_10_3389_fmicb_2017_00792 crossref_primary_10_1089_jir_2014_0225 crossref_primary_10_1093_ibd_izy085 crossref_primary_10_1007_s00394_019_02161_8 crossref_primary_10_1038_ctg_2017_58 crossref_primary_10_1111_cts_12722 crossref_primary_10_3390_microorganisms9051049 crossref_primary_10_2139_ssrn_3305552 crossref_primary_10_3389_fcimb_2021_717636 crossref_primary_10_1016_j_bpg_2013_03_018 crossref_primary_10_3389_fimmu_2017_00397 crossref_primary_10_3748_wjg_v22_i3_949 crossref_primary_10_1007_s11605_018_3744_7 crossref_primary_10_1513_AnnalsATS_201310_339FR crossref_primary_10_1007_s10620_018_5243_9 crossref_primary_10_1016_j_csbj_2021_07_009 crossref_primary_10_3389_fmicb_2022_875238 crossref_primary_10_1016_j_freeradbiomed_2013_11_008 crossref_primary_10_1016_j_ejca_2020_07_026 crossref_primary_10_1038_tpj_2012_43 crossref_primary_10_1093_ibd_izaa103 crossref_primary_10_1097_MIB_0000000000001118 crossref_primary_10_1016_j_carbpol_2021_118415 crossref_primary_10_1016_j_micinf_2009_01_001 crossref_primary_10_1155_2016_6951091 crossref_primary_10_1016_j_phanu_2013_05_002 crossref_primary_10_1142_S0192415X24500502 crossref_primary_10_1186_s13052_020_0781_0 crossref_primary_10_3390_microorganisms9051021 crossref_primary_10_5021_ad_2020_32_4_265 crossref_primary_10_3389_fmicb_2019_01306 crossref_primary_10_1097_01_qco_0000244054_69253_f3 crossref_primary_10_1016_j_lwt_2021_111829 crossref_primary_10_1128_AEM_00880_18 crossref_primary_10_1007_s00109_016_1495_z crossref_primary_10_1016_j_semcancer_2017_06_009 crossref_primary_10_1016_j_jep_2022_115537 crossref_primary_10_1017_S0031182017001263 crossref_primary_10_1038_s41598_021_89185_5 crossref_primary_10_3389_fmicb_2018_02897 crossref_primary_10_1016_j_medmic_2022_100057 crossref_primary_10_1371_journal_pone_0081635 crossref_primary_10_1016_j_avrs_2023_100108 crossref_primary_10_1038_srep02868 crossref_primary_10_1111_j_1472_765X_2007_02129_x crossref_primary_10_1053_j_gastro_2008_01_064 crossref_primary_10_1111_j_1574_6941_2009_00671_x crossref_primary_10_1016_S0399_8320_10_70002_6 crossref_primary_10_3389_fmicb_2024_1489906 crossref_primary_10_1016_j_ijbiomac_2021_03_137 crossref_primary_10_1017_S0007114507832958 crossref_primary_10_1038_emm_2017_24 crossref_primary_10_1038_mi_2017_87 crossref_primary_10_1177_1756284819890534 crossref_primary_10_1016_j_tim_2005_12_007 crossref_primary_10_1177_1756284818769076 crossref_primary_10_1146_annurev_micro_091313_103456 crossref_primary_10_1038_ncomms3304 crossref_primary_10_3390_nu6125786 crossref_primary_10_1007_s12603_014_0513_5 crossref_primary_10_4162_nrp_2024_18_5_663 crossref_primary_10_3390_microorganisms9030565 crossref_primary_10_1016_j_clim_2016_06_002 crossref_primary_10_3748_wjg_v30_i39_4329 crossref_primary_10_4137_MBI_S10819 crossref_primary_10_1038_nrgastro_2013_242 crossref_primary_10_1053_j_gastro_2007_11_059 crossref_primary_10_5264_eiyogakuzashi_81_260 crossref_primary_10_1038_ismej_2007_52 crossref_primary_10_1038_nm1110_1195 crossref_primary_10_3390_cells10102795 crossref_primary_10_1038_s41579_022_00805_x crossref_primary_10_1021_acs_jafc_8b03343 crossref_primary_10_3389_fcimb_2018_00281 crossref_primary_10_1097_DCR_0000000000002568 crossref_primary_10_4166_kjg_2011_58_6_300 crossref_primary_10_1016_j_pathophys_2016_02_002 crossref_primary_10_1111_are_14676 crossref_primary_10_1158_1940_6207_CAPR_14_0129 crossref_primary_10_1155_2022_7813278 crossref_primary_10_3389_fmicb_2020_572921 crossref_primary_10_3892_etm_2021_10757 crossref_primary_10_1128_spectrum_00616_22 crossref_primary_10_3390_nu16223806 crossref_primary_10_1093_annonc_mdz044 crossref_primary_10_1016_j_jcmgh_2020_04_003 crossref_primary_10_1371_journal_pone_0180190 crossref_primary_10_1093_jac_dkq345 crossref_primary_10_1186_1757_4749_1_19 crossref_primary_10_3389_fimmu_2019_03128 crossref_primary_10_3390_nano11082035 crossref_primary_10_1109_TNB_2012_2212204 crossref_primary_10_1007_s12603_014_0549_6 crossref_primary_10_1186_1475_2859_6_22 crossref_primary_10_7759_cureus_48655 crossref_primary_10_1016_j_gtc_2016_09_003 crossref_primary_10_3390_nu11050947 crossref_primary_10_1186_s12876_017_0683_9 crossref_primary_10_7554_eLife_58609 crossref_primary_10_3390_antibiotics11030324 crossref_primary_10_1073_pnas_1000097107 crossref_primary_10_1080_19490976_2021_1930871 crossref_primary_10_3390_cells13020177 crossref_primary_10_1371_journal_pone_0187515 crossref_primary_10_3390_ijms231911728 crossref_primary_10_4110_in_2022_22_e44 crossref_primary_10_1016_j_pathophys_2014_05_002 crossref_primary_10_1002_mbo3_645 crossref_primary_10_1186_2049_2618_1_2 crossref_primary_10_1093_ecco_jcc_jjaa253 crossref_primary_10_1016_j_transproceed_2015_12_040 crossref_primary_10_1186_2049_2618_1_9 crossref_primary_10_1128_JCM_01004_06 crossref_primary_10_1186_1479_7364_7_24 crossref_primary_10_1007_s12275_012_1362_8 crossref_primary_10_1155_2008_626827 crossref_primary_10_1021_acsomega_1c00302 crossref_primary_10_1371_journal_pone_0058005 crossref_primary_10_1016_j_pharmthera_2019_03_006 crossref_primary_10_1007_s00203_022_03069_4 crossref_primary_10_3390_microorganisms10071467 crossref_primary_10_1002_jobm_201500726 crossref_primary_10_1007_s12223_023_01072_w crossref_primary_10_1016_j_jare_2021_07_002 crossref_primary_10_1053_j_gastro_2014_02_009 crossref_primary_10_12938_bmfh_2015_019 crossref_primary_10_1016_j_jnutbio_2014_10_011 crossref_primary_10_1016_j_celrep_2023_112299 crossref_primary_10_1111_vop_12676 crossref_primary_10_1111_1462_2920_12000 crossref_primary_10_1038_scibx_2013_644 crossref_primary_10_3390_cancers13102353 crossref_primary_10_1210_clinem_dgaa166 crossref_primary_10_1186_s12934_016_0596_2 crossref_primary_10_1016_j_molimm_2023_11_013 crossref_primary_10_1097_MCG_0b013e318227414a crossref_primary_10_1039_C5FO00675A crossref_primary_10_1097_MIB_0000000000000674 crossref_primary_10_1016_j_coph_2019_04_018 crossref_primary_10_1053_j_gastro_2019_03_049 crossref_primary_10_1016_j_ebiom_2019_10_002 crossref_primary_10_1016_S1473_3099_07_70260_8 crossref_primary_10_1182_blood_2011_12_401166 crossref_primary_10_1111_j_1574_695X_2012_00935_x crossref_primary_10_3389_fimmu_2023_1264705 crossref_primary_10_1111_j_1365_2125_2008_03096_x crossref_primary_10_3389_frmbi_2023_1301609 crossref_primary_10_1007_s10620_009_0934_x crossref_primary_10_1016_j_amjms_2018_08_005 crossref_primary_10_1016_j_envres_2023_115921 crossref_primary_10_3390_biomedicines10082028 crossref_primary_10_1039_C7FO00305F crossref_primary_10_1053_j_gastro_2010_01_058 crossref_primary_10_1128_AEM_01921_06 crossref_primary_10_1038_ncomms2957 crossref_primary_10_1080_00365521_2020_1803396 crossref_primary_10_1128_AEM_05933_11 crossref_primary_10_1007_s11894_013_0313_9 crossref_primary_10_1016_j_jhep_2016_11_008 crossref_primary_10_3390_pathogens10060761 crossref_primary_10_1111_febs_16888 crossref_primary_10_1186_s13099_019_0291_z crossref_primary_10_3389_fcimb_2021_549678 crossref_primary_10_1002_fft2_147 crossref_primary_10_1155_2014_928461 crossref_primary_10_1093_hmg_ddr353 crossref_primary_10_1111_j_1365_2958_2006_05056_x crossref_primary_10_1007_s00384_016_2548_z crossref_primary_10_4161_gmic_28572 crossref_primary_10_1007_s11596_017_1767_z crossref_primary_10_1186_s12866_021_02173_7 crossref_primary_10_1186_1475_2891_8_49 crossref_primary_10_1128_microbiolspec_BAD_0005_2016 crossref_primary_10_1155_2022_9621668 crossref_primary_10_1007_s00281_017_0658_5 crossref_primary_10_1016_j_thromres_2020_03_003 crossref_primary_10_3389_fimmu_2021_694217 crossref_primary_10_1093_ecco_jcc_jjac029 crossref_primary_10_1371_journal_pone_0173818 crossref_primary_10_2147_IJN_S493434 crossref_primary_10_3389_fnins_2022_792996 crossref_primary_10_1111_nph_14560 crossref_primary_10_1186_s40168_024_01758_4 crossref_primary_10_1016_j_gpb_2016_02_005 crossref_primary_10_3389_fmicb_2019_02259 crossref_primary_10_1371_journal_pone_0062544 crossref_primary_10_1097_PSY_0000000000000470 crossref_primary_10_3390_jcm10215077 crossref_primary_10_1155_2013_425146 crossref_primary_10_3390_jcm11237074 crossref_primary_10_1021_acs_jafc_4c00867 crossref_primary_10_1093_jnci_djt300 crossref_primary_10_1146_annurev_food_030810_110338 crossref_primary_10_1002_ibd_20392 crossref_primary_10_1074_jbc_M111_271007 crossref_primary_10_3390_ijerph20054624 crossref_primary_10_1039_b705657e crossref_primary_10_1186_s12866_021_02414_9 crossref_primary_10_1093_toxsci_kfv259 crossref_primary_10_1097_MEG_0000000000001842 crossref_primary_10_3109_00365521_2014_910834 crossref_primary_10_1038_nrgastro_2012_44 crossref_primary_10_1016_j_biopha_2023_115311 crossref_primary_10_3390_ijms242417630 crossref_primary_10_1186_s40168_016_0200_3 crossref_primary_10_1093_femsec_fiv008 crossref_primary_10_1080_19490976_2020_1725220 crossref_primary_10_1089_jmf_2008_0163 crossref_primary_10_1371_journal_pone_0066934 crossref_primary_10_3748_wjg_v21_i41_11862 crossref_primary_10_1016_j_bbcan_2023_188897 crossref_primary_10_1055_a_2062_9552 crossref_primary_10_1186_1471_2164_15_37 crossref_primary_10_3390_nu14020260 crossref_primary_10_1097_MEG_0000000000000989 crossref_primary_10_1371_journal_pone_0049138 crossref_primary_10_1186_1756_0500_7_50 crossref_primary_10_1016_j_chom_2014_08_014 crossref_primary_10_1007_s41975_023_00283_1 crossref_primary_10_1111_febs_16449 crossref_primary_10_1186_s10020_019_0102_5 crossref_primary_10_1038_s41418_021_00876_y crossref_primary_10_7554_eLife_50240 crossref_primary_10_3389_frmbi_2023_1174034 crossref_primary_10_1016_j_bpobgyn_2023_102365 crossref_primary_10_3389_fmmed_2023_1046414 crossref_primary_10_1186_1471_230X_10_134 crossref_primary_10_3390_ph14080708 crossref_primary_10_1016_j_isci_2020_101875 crossref_primary_10_1007_s12161_014_9923_6 crossref_primary_10_1111_1348_0421_13191 crossref_primary_10_1186_s12876_016_0534_0 crossref_primary_10_1186_s13287_022_03118_1 crossref_primary_10_1111_imm_13833 crossref_primary_10_1038_s41575_023_00854_4 crossref_primary_10_1097_MIB_0000000000000602 crossref_primary_10_1155_2020_6675206 crossref_primary_10_3390_vaccines10020244 crossref_primary_10_1111_cei_13049 crossref_primary_10_1016_j_phrs_2015_04_005 crossref_primary_10_1586_1744666X_4_2_133 crossref_primary_10_1093_ecco_jcc_jjab144 crossref_primary_10_3389_fmicb_2021_735562 crossref_primary_10_3389_fimmu_2018_03177 crossref_primary_10_1111_apm_12609 crossref_primary_10_1038_s41598_019_56631_4 crossref_primary_10_1111_cei_13040 crossref_primary_10_1016_j_jbspin_2013_02_005 crossref_primary_10_1099_ijs_0_003087_0 crossref_primary_10_3920_BM2017_0097 crossref_primary_10_1007_s00394_019_01910_z crossref_primary_10_1038_s41565_023_01346_x crossref_primary_10_3389_fmicb_2017_02242 crossref_primary_10_1016_j_jff_2019_103641 crossref_primary_10_3389_fmicb_2024_1481496 crossref_primary_10_3390_nu7031798 crossref_primary_10_4161_gmic_1_4_12520 crossref_primary_10_1016_j_coi_2014_08_004 crossref_primary_10_1093_ecco_jcc_jjw051 crossref_primary_10_3390_cancers12082038 crossref_primary_10_1007_s10620_006_9682_3 crossref_primary_10_1099_jmm_0_47719_0 crossref_primary_10_1111_j_1749_6632_2011_06340_x crossref_primary_10_1093_advances_nmy125 crossref_primary_10_1097_QCO_0000000000000300 crossref_primary_10_1111_j_1365_2362_2008_01966_x crossref_primary_10_1080_19490976_2014_997612 crossref_primary_10_1016_j_giec_2019_02_005 crossref_primary_10_3233_MNM_17182 crossref_primary_10_1038_nbt_3870 crossref_primary_10_1021_acs_jafc_9b04411 crossref_primary_10_1016_j_tvjl_2015_10_033 crossref_primary_10_1016_j_ygeno_2013_08_004 crossref_primary_10_1152_ajpgi_00360_2020 crossref_primary_10_1186_s40168_021_01028_7 crossref_primary_10_1016_j_neuint_2020_104938 crossref_primary_10_36233_0372_9311_192 crossref_primary_10_1016_j_copbio_2010_03_009 crossref_primary_10_1016_j_dld_2018_11_021 crossref_primary_10_1016_j_annder_2024_103290 crossref_primary_10_1186_s13099_021_00447_z crossref_primary_10_1538_expanim_20_0129 crossref_primary_10_1007_s00213_020_05520_0 crossref_primary_10_2217_fmb_14_22 crossref_primary_10_1016_j_jevs_2019_01_018 crossref_primary_10_3389_fcimb_2021_772962 crossref_primary_10_1080_10717544_2024_2415580 crossref_primary_10_1107_S1399004715009803 crossref_primary_10_1155_2018_1781036 crossref_primary_10_1002_ibd_20442 crossref_primary_10_4161_gmic_29810 crossref_primary_10_1016_j_coi_2012_05_007 crossref_primary_10_1097_MOG_0b013e3282f2b0e8 crossref_primary_10_1097_MS9_0000000000000408 crossref_primary_10_1128_mBio_02120_17 crossref_primary_10_1038_ajg_2011_308 crossref_primary_10_21518_2079_701X_2021_12_200_208 crossref_primary_10_1038_ajg_2011_304 crossref_primary_10_3390_ijms241914619 crossref_primary_10_3389_fmicb_2016_00446 crossref_primary_10_22424_jmsb_2019_37_1_27 crossref_primary_10_1016_j_ijmm_2007_07_016 crossref_primary_10_1038_s41564_017_0075_5 crossref_primary_10_1016_j_cgh_2013_03_036 crossref_primary_10_1002_ncp_10489 crossref_primary_10_1016_j_nantod_2017_08_006 crossref_primary_10_1016_j_shpsc_2007_09_001 crossref_primary_10_1016_j_syapm_2015_03_004 crossref_primary_10_1038_s41591_019_0405_7 crossref_primary_10_4049_jimmunol_1601621 crossref_primary_10_3390_nu13072125 crossref_primary_10_1113_JP275396 crossref_primary_10_1007_s10620_015_3726_5 crossref_primary_10_1016_j_clp_2018_01_008 crossref_primary_10_3390_md14120224 crossref_primary_10_1586_14737159_6_3_345 crossref_primary_10_1177_17562848231207280 crossref_primary_10_1016_j_jff_2022_104956 crossref_primary_10_3389_fimmu_2023_1156397 crossref_primary_10_1186_s13293_022_00422_6 crossref_primary_10_1038_ismej_2012_39 crossref_primary_10_1111_apt_14454 crossref_primary_10_3390_microorganisms9071449 crossref_primary_10_1097_MPG_0b013e3181615b3a crossref_primary_10_1002_ibd_21751 crossref_primary_10_1002_kjm2_12459 crossref_primary_10_1093_ecco_jcc_jjy207 crossref_primary_10_1007_s40265_023_01871_y crossref_primary_10_3389_fmicb_2015_01285 crossref_primary_10_1093_ecco_jcc_jjw024 crossref_primary_10_1007_s00253_015_7205_x crossref_primary_10_1016_j_psj_2019_10_029 crossref_primary_10_1016_j_lpm_2016_02_008 crossref_primary_10_1053_j_gastro_2011_07_046 crossref_primary_10_2217_dmt_11_24 crossref_primary_10_1017_S0007114520000896 crossref_primary_10_1038_mi_2016_67 crossref_primary_10_1177_1756284818822250 crossref_primary_10_1128_spectrum_00425_21 crossref_primary_10_1371_journal_pone_0052132 crossref_primary_10_1016_j_micpath_2020_104251 crossref_primary_10_14309_ctg_0000000000000547 crossref_primary_10_1016_j_scitotenv_2021_150685 crossref_primary_10_1038_nature08821 crossref_primary_10_1093_ecco_jcc_jjv147 crossref_primary_10_3390_jcm9082448 crossref_primary_10_1155_2013_636785 crossref_primary_10_1371_journal_pone_0032545 crossref_primary_10_1016_j_cytogfr_2017_12_002 crossref_primary_10_1186_s12917_018_1691_x crossref_primary_10_1111_j_1365_2036_2009_04034_x crossref_primary_10_1038_nrgastro_2012_152 crossref_primary_10_2174_1389450121666201020160803 crossref_primary_10_1097_MNH_0000000000000262 crossref_primary_10_1093_ecco_jcc_jjac064 crossref_primary_10_3389_fphar_2020_00538 crossref_primary_10_1093_ecco_jcc_jjac065 crossref_primary_10_5005_jp_jogi_5_1_5 crossref_primary_10_1128_cmr_00133_23 crossref_primary_10_3917_heg_062_0119 crossref_primary_10_1007_s11306_020_01671_5 crossref_primary_10_1016_j_imlet_2014_07_017 crossref_primary_10_1111_j_1399_3038_2012_01328_x crossref_primary_10_1097_MCG_0b013e31827b4f94 crossref_primary_10_1080_21688370_2018_1539595 crossref_primary_10_3390_ijms17040578 crossref_primary_10_1111_apt_12282 crossref_primary_10_1093_dnares_dsn033 crossref_primary_10_1021_jf402441f crossref_primary_10_1080_1744666X_2021_1935877 crossref_primary_10_1007_s40588_024_00227_8 crossref_primary_10_3389_fcimb_2020_544704 crossref_primary_10_3389_fnut_2022_876112 crossref_primary_10_1038_srep10514 crossref_primary_10_1007_s00253_015_6582_5 crossref_primary_10_1155_2015_931574 crossref_primary_10_1080_10934529_2012_668064 crossref_primary_10_3109_00365521_2014_966320 crossref_primary_10_1097_QAD_0b013e3282fc972e crossref_primary_10_1007_s12016_018_8690_3 crossref_primary_10_1080_07315724_2014_983249 crossref_primary_10_5411_wji_v3_i3_31 crossref_primary_10_1016_j_ijmm_2018_04_008 crossref_primary_10_3389_fimmu_2015_00558 crossref_primary_10_1016_j_jss_2015_12_008 crossref_primary_10_3389_fimmu_2015_00555 crossref_primary_10_1186_1471_2105_14_136 crossref_primary_10_1186_gb_2012_13_9_r79 crossref_primary_10_1093_g3journal_jkac293 crossref_primary_10_1051_medsci_20163211009 crossref_primary_10_1097_MEG_0000000000002050 crossref_primary_10_1111_j_1365_2036_2008_03860_x crossref_primary_10_1016_j_fct_2016_06_015 crossref_primary_10_7554_eLife_89776 crossref_primary_10_1186_s40168_017_0384_1 crossref_primary_10_1186_s13054_016_1491_2 crossref_primary_10_1021_acs_biochem_8b01006 crossref_primary_10_1111_1751_2980_12081 crossref_primary_10_1093_ecco_jcc_jjv102 crossref_primary_10_1021_ac401776k crossref_primary_10_1016_j_febslet_2014_05_007 crossref_primary_10_1172_JCI62236 crossref_primary_10_1186_1757_4749_4_19 crossref_primary_10_3390_fermentation7030156 crossref_primary_10_1186_1757_4749_4_12 crossref_primary_10_1111_j_1365_2036_2006_03053_x crossref_primary_10_1016_j_mimet_2013_10_006 crossref_primary_10_1136_gutjnl_2015_309940 crossref_primary_10_4161_gmic_20169 crossref_primary_10_1080_17474124_2019_1671822 crossref_primary_10_1093_ecco_jcc_jjv119 crossref_primary_10_1136_bmjopen_2019_031137 crossref_primary_10_1111_odi_12589 crossref_primary_10_1186_gb_2011_12_6_r60 crossref_primary_10_1016_j_cell_2018_02_044 crossref_primary_10_2334_josnusd_16_0722 crossref_primary_10_2165_11632710_000000000_00000 crossref_primary_10_1096_fj_10_177980 crossref_primary_10_3389_fimmu_2023_1004756 crossref_primary_10_1186_s12903_023_03442_9 crossref_primary_10_3390_nu12082337 crossref_primary_10_1002_art_38892 crossref_primary_10_1002_ibd_20818 crossref_primary_10_1038_s41598_017_04672_y crossref_primary_10_1172_jci_insight_86907 crossref_primary_10_3389_fcell_2021_719072 crossref_primary_10_1186_1471_2180_8_79 crossref_primary_10_3389_fmicb_2020_01553 crossref_primary_10_3389_fcimb_2021_599734 crossref_primary_10_1155_2021_4192451 crossref_primary_10_3389_fmicb_2016_00455 crossref_primary_10_3389_fmicb_2019_01655 crossref_primary_10_1016_j_bpg_2014_04_008 crossref_primary_10_3389_fimmu_2019_00554 crossref_primary_10_1073_pnas_1504887113 crossref_primary_10_1073_pnas_0809363105 crossref_primary_10_1097_MIB_0000000000000382 crossref_primary_10_1038_s41598_022_04773_3 crossref_primary_10_3390_microorganisms12112333 crossref_primary_10_1177_2050640616663689 crossref_primary_10_1016_j_cegh_2023_101497 crossref_primary_10_1038_srep43465 crossref_primary_10_1016_j_vaccine_2018_04_066 crossref_primary_10_3389_fsurg_2022_882625 crossref_primary_10_3390_nu12082347 crossref_primary_10_1002_bies_201500151 crossref_primary_10_1016_j_jpeds_2016_08_044 crossref_primary_10_4103_jmgims_jmgims_59_19 crossref_primary_10_1016_j_psj_2020_03_062 crossref_primary_10_3390_nu12123759 crossref_primary_10_1080_19490976_2016_1241933 crossref_primary_10_1016_j_ijmm_2016_03_004 crossref_primary_10_1111_apt_12665 crossref_primary_10_1007_s00108_022_01396_8 crossref_primary_10_3389_fmicb_2016_00462 crossref_primary_10_1017_S175173111800040X crossref_primary_10_3390_cells13050381 crossref_primary_10_3390_microorganisms8020200 crossref_primary_10_1016_j_jpeds_2016_08_049 crossref_primary_10_1136_gutjnl_2015_309990 crossref_primary_10_4199_C00047ED1V01Y201110ISP029 crossref_primary_10_1155_2021_6417658 crossref_primary_10_3389_fimmu_2017_00255 crossref_primary_10_5483_BMBRep_2017_50_11_165 crossref_primary_10_1371_journal_pcbi_1003706 crossref_primary_10_1146_annurev_food_030212_182554 crossref_primary_10_1017_S0029665114000639 crossref_primary_10_11569_wcjd_v27_i10_605 crossref_primary_10_3390_nu12123749 crossref_primary_10_3748_wjg_v20_i42_15650 crossref_primary_10_4161_19490976_2014_972241 crossref_primary_10_3389_fimmu_2019_02754 crossref_primary_10_7717_peerj_9622 crossref_primary_10_1038_nrgastro_2017_88 crossref_primary_10_1038_s41598_023_33050_0 crossref_primary_10_1136_gutjnl_2012_303786 crossref_primary_10_1039_c2mb25133g crossref_primary_10_1097_INF_0000000000002103 crossref_primary_10_4103_ghep_ghep_18_22 crossref_primary_10_1111_j_1753_4887_2012_00498_x crossref_primary_10_1371_journal_pone_0140301 crossref_primary_10_1038_nrgastro_2014_167 crossref_primary_10_1371_journal_pone_0192066 crossref_primary_10_1080_15659801_2015_1042768 crossref_primary_10_1016_S0399_8320_06_73301_2 crossref_primary_10_3748_wjg_v20_i42_15657 crossref_primary_10_3390_nu11112629 crossref_primary_10_1016_j_chom_2015_12_016 crossref_primary_10_1371_journal_ppat_1006653 crossref_primary_10_1136_gutjnl_2014_308341 crossref_primary_10_1186_1471_2334_11_210 crossref_primary_10_1038_srep09131 crossref_primary_10_1016_j_fshw_2017_07_003 crossref_primary_10_1080_00439339_2023_2298513 crossref_primary_10_3389_fimmu_2022_1026511 crossref_primary_10_1007_s10646_021_02407_4 crossref_primary_10_1111_j_1440_1746_2010_06498_x crossref_primary_10_1007_s11250_020_02538_6 crossref_primary_10_1086_523336 crossref_primary_10_1152_ajpgi_00114_2016 crossref_primary_10_1080_09168451_2015_1006566 crossref_primary_10_1038_nature12506 crossref_primary_10_3389_fmicb_2017_01703 crossref_primary_10_1016_j_jbc_2025_108320 crossref_primary_10_3389_fmicb_2020_615404 crossref_primary_10_3390_biom13111569 crossref_primary_10_1016_j_clim_2017_07_001 crossref_primary_10_7717_peerj_6200 crossref_primary_10_1016_j_csbj_2021_11_037 crossref_primary_10_1016_j_jaci_2011_04_060 crossref_primary_10_1002_hep_28829 crossref_primary_10_1111_jmp_12730 crossref_primary_10_1053_j_gastro_2023_11_304 crossref_primary_10_3390_cells8010033 crossref_primary_10_3390_microorganisms7100440 crossref_primary_10_3748_wjg_v24_i28_3130 crossref_primary_10_1038_s41385_021_00466_8 crossref_primary_10_1097_MOG_0b013e32830007f7 crossref_primary_10_3390_biomedicines10020289 crossref_primary_10_1093_ibd_izy371 crossref_primary_10_1128_spectrum_00388_24 crossref_primary_10_1017_S0007114514003274 crossref_primary_10_1038_nmeth964 crossref_primary_10_1093_burnst_tkad004 crossref_primary_10_1016_j_jinf_2018_10_005 crossref_primary_10_3389_fcimb_2022_932373 crossref_primary_10_1177_1756283X12459294 crossref_primary_10_1159_000495115 crossref_primary_10_1038_s41467_024_53832_y crossref_primary_10_1371_journal_pone_0146162 crossref_primary_10_1016_j_csbj_2022_04_006 crossref_primary_10_1093_ibd_izx033 crossref_primary_10_35712_aig_v2_i4_111 crossref_primary_10_3390_s22062316 crossref_primary_10_1016_j_mib_2015_01_007 crossref_primary_10_1016_j_jtauto_2019_100032 crossref_primary_10_1186_1757_4749_3_7 crossref_primary_10_1126_scitranslmed_aah6888 crossref_primary_10_1186_gm446 crossref_primary_10_1016_j_heliyon_2021_e08194 crossref_primary_10_1016_j_tjnut_2023_11_001 crossref_primary_10_3390_jcm10184055 crossref_primary_10_1007_BF02829968 crossref_primary_10_1007_s00535_010_0368_4 crossref_primary_10_1053_j_gastro_2015_05_041 crossref_primary_10_1007_s00702_019_02083_z crossref_primary_10_1016_j_smim_2006_09_001 crossref_primary_10_3389_fmed_2022_1068567 crossref_primary_10_1016_j_yexmp_2021_104642 crossref_primary_10_3389_fimmu_2023_1143526 crossref_primary_10_1016_S0399_8320_10_70007_5 crossref_primary_10_1007_s11033_024_09273_3 crossref_primary_10_1556_030_2021_01498 crossref_primary_10_3390_cancers13092124 crossref_primary_10_1093_ilar_ilv030 crossref_primary_10_1016_j_gtc_2012_08_003 crossref_primary_10_1155_2015_167249 crossref_primary_10_1093_ilar_ilv019 crossref_primary_10_1136_gutjnl_2016_312137 crossref_primary_10_1152_ajpgi_00184_2013 crossref_primary_10_1016_j_jneuroim_2018_07_015 crossref_primary_10_3393_jksc_2008_24_4_302 crossref_primary_10_1371_journal_pone_0207111 crossref_primary_10_3390_ijms222111359 crossref_primary_10_1016_j_trsl_2020_03_012 crossref_primary_10_1111_sji_12805 crossref_primary_10_1038_mi_2011_9 crossref_primary_10_1097_MIB_0000000000000776 crossref_primary_10_4166_kjg_2010_56_6_394 crossref_primary_10_1136_postgradmedj_2015_133285 crossref_primary_10_1007_s12602_024_10335_y crossref_primary_10_1007_s00281_019_00756_1 crossref_primary_10_1016_j_trsl_2016_06_002 crossref_primary_10_1038_s41598_018_37298_9 crossref_primary_10_3390_microorganisms10071371 crossref_primary_10_3390_cimb45050249 crossref_primary_10_1016_j_biotechadv_2016_08_003 crossref_primary_10_1016_S0007_9960_07_91322_X crossref_primary_10_2217_17460913_2_3_285 crossref_primary_10_1146_annurev_pathol_1_110304_100128 crossref_primary_10_1016_j_imlet_2013_01_007 crossref_primary_10_1101_gr_108332_110 crossref_primary_10_3390_nu12020551 crossref_primary_10_1002_ibd_20084 crossref_primary_10_1038_nrrheum_2016_85 crossref_primary_10_1021_pr300900b crossref_primary_10_1159_000504148 crossref_primary_10_1097_MIB_0000000000000793 crossref_primary_10_1080_14789450_2018_1523724 crossref_primary_10_1093_nar_gkx1209 crossref_primary_10_1136_gutjnl_2015_310027 crossref_primary_10_3390_ijms24021254 crossref_primary_10_1038_s41591_019_0377_7 crossref_primary_10_1016_j_chom_2012_10_012 crossref_primary_10_1007_s10620_020_06090_z crossref_primary_10_1016_j_jaut_2015_07_003 crossref_primary_10_1016_j_semcancer_2020_07_006 crossref_primary_10_1097_MD_0000000000018476 crossref_primary_10_1080_00365521_2018_1447597 crossref_primary_10_1007_s00253_021_11646_8 crossref_primary_10_1172_jci_insight_148543 crossref_primary_10_1038_s41396_019_0357_4 crossref_primary_10_1038_s41586_019_1238_8 crossref_primary_10_1089_mdr_2009_0916 crossref_primary_10_1097_MOG_0b013e32833f1195 crossref_primary_10_3390_metabo11060406 crossref_primary_10_1016_S0399_8320_10_70020_8 crossref_primary_10_1016_j_chom_2025_01_002 crossref_primary_10_7554_eLife_89776_3 crossref_primary_10_7759_cureus_19343 crossref_primary_10_3390_ijms22031416 crossref_primary_10_1016_j_biochi_2021_02_010 crossref_primary_10_1080_19490976_2014_1000080 crossref_primary_10_3389_fonc_2020_00902 crossref_primary_10_1016_j_taap_2020_114900 crossref_primary_10_1016_j_micpath_2023_106159 crossref_primary_10_1016_j_bspc_2024_105984 crossref_primary_10_4291_wjgp_v3_i1_27 crossref_primary_10_3389_fphys_2021_715506 crossref_primary_10_3390_ijms222011255 crossref_primary_10_1093_infdis_jiu409 crossref_primary_10_4161_gmic_1_3_12485 crossref_primary_10_1038_ismej_2016_13 crossref_primary_10_1177_1098612X221077876 crossref_primary_10_1186_s12866_014_0250_2 crossref_primary_10_1186_1476_7961_6_11 crossref_primary_10_1159_000354902 crossref_primary_10_26599_FSHW_2022_9250180 crossref_primary_10_3390_ijms25010561 crossref_primary_10_1136_archdischild_2016_311643 crossref_primary_10_1016_j_dld_2012_04_014 crossref_primary_10_1111_j_1574_6941_2011_01252_x crossref_primary_10_1111_jgh_14432 crossref_primary_10_1002_ibd_21366 crossref_primary_10_1016_j_compbiolchem_2014_08_016 crossref_primary_10_4103_2045_9912_390251 crossref_primary_10_3390_ijms222011243 crossref_primary_10_1098_rstb_2015_0500 crossref_primary_10_37349_ei_2021_00008 crossref_primary_10_1007_s15034_018_1347_8 crossref_primary_10_1007_s12328_017_0813_5 crossref_primary_10_3390_ijms24065673 crossref_primary_10_1136_gutjnl_2021_326828 crossref_primary_10_1136_bmjopen_2017_021233 crossref_primary_10_1093_ibd_izy318 crossref_primary_10_1128_JCM_00312_06 crossref_primary_10_1155_2021_7479540 crossref_primary_10_1186_s12876_016_0437_0 crossref_primary_10_1080_1745039X_2019_1614849 crossref_primary_10_3390_ijms22063076 crossref_primary_10_1002_ibd_21354 crossref_primary_10_1152_ajpgi_00154_2011 crossref_primary_10_2217_pgs_2020_0044 crossref_primary_10_1039_D0FO00713G crossref_primary_10_3748_wjg_v20_i40_14805 crossref_primary_10_3389_fmicb_2018_03062 crossref_primary_10_3390_nu8120728 crossref_primary_10_1016_j_idc_2010_07_008 crossref_primary_10_1371_journal_pcbi_1004573 crossref_primary_10_3389_fcimb_2021_631972 crossref_primary_10_1128_AEM_00362_14 crossref_primary_10_1186_1471_2180_10_63 crossref_primary_10_3390_microorganisms9050977 crossref_primary_10_1007_s00109_011_0802_y crossref_primary_10_1038_nrmicro2403 crossref_primary_10_1038_s41522_017_0022_5 crossref_primary_10_1242_jeb_001370 crossref_primary_10_4161_gmic_19934 crossref_primary_10_3390_children8070554 crossref_primary_10_1038_nrmicro_2017_58 crossref_primary_10_1039_C9FO01142K crossref_primary_10_1096_fj_10_156190 crossref_primary_10_1038_s41598_018_23261_1 crossref_primary_10_7759_cureus_54569 crossref_primary_10_1093_jambio_lxae086 crossref_primary_10_1136_gutjnl_2013_305320 crossref_primary_10_1002_ibd_21319 crossref_primary_10_1016_j_pt_2017_04_004 crossref_primary_10_1097_MIB_0000000000000717 crossref_primary_10_1053_j_gastro_2010_08_049 crossref_primary_10_1007_s00284_018_1468_2 crossref_primary_10_3390_diagnostics11081376 crossref_primary_10_1128_mbio_00078_24 crossref_primary_10_1093_cvr_cvaa128 crossref_primary_10_1136_archdischild_2018_316659 crossref_primary_10_1053_j_gastro_2011_01_054 crossref_primary_10_1097_01_MIB_0000440815_76627_64 crossref_primary_10_1097_MIB_0000000000000710
ContentType	Journal Article
Copyright	Copyright 2006 by Gut 2006 INIST-CNRS Copyright: 2006 Copyright 2006 by Gut Distributed under a Creative Commons Attribution 4.0 International License Copyright © 2006 BMJ Publishing Group & British Society of Gastroenterology
Copyright_xml	– notice: Copyright 2006 by Gut – notice: 2006 INIST-CNRS – notice: Copyright: 2006 Copyright 2006 by Gut – notice: Distributed under a Creative Commons Attribution 4.0 International License – notice: Copyright © 2006 BMJ Publishing Group & British Society of Gastroenterology
DBID	BSCLL AAYXX CITATION IQODW CGR CUY CVF ECM EIF NPM 3V. 7X7 7XB 88E 88I 8AF 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA AZQEC BBNVY BENPR BHPHI BTHHO CCPQU DWQXO FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M2P M7P PHGZM PHGZT PJZUB PKEHL PPXIY PQEST PQGLB PQQKQ PQUKI PRINS Q9U 7QL 7T7 8FD C1K FR3 P64 RC3 7X8 1XC VOOES 5PM
DOI	10.1136/gut.2005.073817
DatabaseName	Istex CrossRef Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed ProQuest Central (Corporate) Health & Medical Collection (Proquest) ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Science Database (Alumni Edition) STEM Database ProQuest SciTech Collection ProQuest Natural Science Journals Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland ProQuest Central Essentials Biological Science Database ProQuest Central Natural Science Collection BMJ Journals ProQuest One Community College ProQuest Central Korea Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student ProQuest SciTech Premium Collection ProQuest Health & Medical Complete (Alumni) Biological Sciences Health & Medical Collection (Alumni) Proquest Medical Database Science Database Biological Science Database ProQuest Central Premium ProQuest One Academic ProQuest Health & Medical Research Collection ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Applied & Life Sciences ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China ProQuest Central Basic Bacteriology Abstracts (Microbiology B) Industrial and Applied Microbiology Abstracts (Microbiology A) Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database Biotechnology and BioEngineering Abstracts Genetics Abstracts MEDLINE - Academic Hyper Article en Ligne (HAL) Hyper Article en Ligne (HAL) (Open Access) PubMed Central (Full Participant titles)
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) ProQuest Central Student ProQuest One Academic Middle East (New) ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest AP Science ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest One Health & Nursing ProQuest Natural Science Collection ProQuest Central China ProQuest Central ProQuest One Applied & Life Sciences ProQuest Health & Medical Research Collection Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Health & Medical Research Collection Biological Science Collection ProQuest Central (New) ProQuest Medical Library (Alumni) ProQuest Science Journals (Alumni Edition) ProQuest Biological Science Collection ProQuest Central Basic ProQuest Science Journals ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition BMJ Journals ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) Genetics Abstracts Technology Research Database Bacteriology Abstracts (Microbiology B) Engineering Research Database Industrial and Applied Microbiology Abstracts (Microbiology A) Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management MEDLINE - Academic
DatabaseTitleList	ProQuest Central Student Genetics Abstracts MEDLINE MEDLINE - Academic
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 3 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Medicine
EISSN	1468-3288
EndPage	211
ExternalDocumentID	PMC1856500 oai_HAL_hal_02667954v1 4014170481 16188921 17402321 10_1136_gut_2005_073817 ark_67375_NVC_M53D7CJV_1 gutjnl
Genre	Research Support, Non-U.S. Gov't Journal Article
GroupedDBID	--- .55 .GJ .VT 08G 0R~ 18M 29I 2WC 354 39C 3O- 4.4 40O 53G 5GY 5VS 7X7 7~S 88E 88I 8AF 8F7 8FE 8FH 8FI 8FJ 8R4 8R5 AAHLL AAKAS AAOJX AAUVZ AAWJN AAYEP ABAAH ABKDF ABMQD ABOCM ABTFR ABUWG ABVAJ ACGFO ACGFS ACGOD ACGTL ACHTP ACMFJ ACOAB ACOFX ACQSR ACTZY ADBBV ADCEG ADFRT ADUGQ ADZCM AENEX AFKRA AFWFF AGQPQ AHMBA AHNKE AHQMW AI. AJYBZ ALIPV ALMA_UNASSIGNED_HOLDINGS ASPBG AVWKF AZFZN AZQEC BAWUL BBNVY BENPR BHPHI BLJBA BOMFT BPHCQ BTFSW BTHHO BVXVI C1A C45 CAG CCPQU COF CS3 CXRWF DIK DU5 DWQXO E3Z EBS EJD F5P FD8 FEDTE FYUFA GNUQQ GX1 H13 HAJ HCIFZ HMCUK HVGLF HYE HZ~ IAO IEA IH2 IHR INH INR IOF ITC J5H KQ8 L7B LK8 M1P M2P M7P N9A NTWIH NXWIF O9- OK1 OVD P2P PHGZT PQQKQ PROAC PSQYO Q2X R53 RHI RMJ RPM RV8 TEORI TR2 UKHRP UYXKK V24 VH1 VM9 VVN W8F WH7 WOQ X7M YFH YOC YQY ZGI ZXP ZY1 3V. ABJNI BSCLL RHF AAYXX ACQHZ ADGHP AERUA CITATION PHGZM IQODW PJZUB PPXIY PQGLB CGR CUY CVF ECM EIF NPM PKN 7XB 8FK K9. PKEHL PQEST PQUKI PRINS Q9U 7QL 7T7 8FD C1K FR3 P64 RC3 7X8 1XC VOOES 5PM
ID	FETCH-LOGICAL-b587t-59aa3360afb0410cc4c301b7f861480b76a2fb937b6ba6ecfff081c6c6e32b5c3
IEDL.DBID	7X7
ISSN	0017-5749
IngestDate	Thu Aug 21 13:37:37 EDT 2025 Fri May 09 12:18:00 EDT 2025 Fri Jul 11 08:53:47 EDT 2025 Mon Jul 21 11:45:43 EDT 2025 Fri Jul 25 11:45:43 EDT 2025 Wed Feb 19 01:36:06 EST 2025 Mon Jul 21 09:13:01 EDT 2025 Tue Jul 01 04:11:15 EDT 2025 Thu Apr 24 23:05:34 EDT 2025 Wed Oct 30 09:31:44 EDT 2024 Thu Apr 24 23:05:38 EDT 2025
IsDoiOpenAccess	true
IsOpenAccess	true
IsPeerReviewed	true
IsScholarly	true
Issue	2
Keywords	Crohn disease Gastroenterology Digestive diseases Intestinal disease Surgical approach Feces Inflammatory disease PHYLOGENY 16S rRNA CROHN'S DISEASE FAECAL MICROBIOTA METAGENOME FIRMICUTES FLUORESCENT IN SITU HIBRIDIZATION
Language	English
License	CC BY 4.0 Distributed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-b587t-59aa3360afb0410cc4c301b7f861480b76a2fb937b6ba6ecfff081c6c6e32b5c3
Notes	Correspondence to:  Dr J Dore  INRA-UEPSD, 78350 Jouy-en-Josas, France; joel.dore@jouy.inra.fr local:0550205 ark:/67375/NVC-M53D7CJV-1 href:gutjnl-55-205.pdf istex:DEEC691B1829E82F8F0E83A441AA12AD57FC78DA PMID:16188921 ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 content type line 23
ORCID	0000-0003-1561-7700 0000-0003-4228-1712
OpenAccessLink	https://hal.inrae.fr/hal-02667954
PMID	16188921
PQID	1779335330
PQPubID	2041069
PageCount	7
ParticipantIDs	pubmedcentral_primary_oai_pubmedcentral_nih_gov_1856500 hal_primary_oai_HAL_hal_02667954v1 proquest_miscellaneous_70682916 proquest_miscellaneous_19433594 proquest_journals_1779335330 pubmed_primary_16188921 pascalfrancis_primary_17402321 crossref_primary_10_1136_gut_2005_073817 crossref_citationtrail_10_1136_gut_2005_073817 istex_primary_ark_67375_NVC_M53D7CJV_1 bmj_primary_10_1136_gut_2005_073817
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	2006-02-01
PublicationDateYYYYMMDD	2006-02-01
PublicationDate_xml	– month: 02 year: 2006 text: 2006-02-01 day: 01
PublicationDecade	2000
PublicationPlace	London
PublicationPlace_xml	– name: London – name: England
PublicationTitle	Gut
PublicationTitleAlternate	Gut
PublicationYear	2006
Publisher	BMJ Publishing Group Ltd and British Society of Gastroenterology BMJ BMJ Publishing Group LTD BMJ Publishing Group BMJ Group
Publisher_xml	– name: BMJ Publishing Group Ltd and British Society of Gastroenterology – name: BMJ – name: BMJ Publishing Group LTD – name: BMJ Publishing Group – name: BMJ Group
References	11823207 - Appl Environ Microbiol. 2002 Feb;68(2):673-90 15184153 - Appl Environ Microbiol. 2004 Jun;70(6):3528-34 4598229 - Appl Microbiol. 1974 May;27(5):961-79 12324374 - Appl Environ Microbiol. 2002 Oct;68(10):5186-90 10831436 - Appl Environ Microbiol. 2000 Jun;66(6):2541-7 14684564 - Gut. 2004 Jan;53(1):1-4 10543789 - Appl Environ Microbiol. 1999 Nov;65(11):4799-807 15703577 - Curr Opin Gastroenterol. 2003 Jul;19(4):358-65 12363017 - Microbiol Immunol. 2002;46(8):535-48 10742256 - Appl Environ Microbiol. 2000 Apr;66(4):1654-61 12520046 - Nucleic Acids Res. 2003 Jan 1;31(1):442-3 11152940 - FEMS Microbiol Rev. 2001 Jan;25(1):39-67 8902363 - Comput Appl Biosci. 1996 Aug;12(4):357-8 9212428 - Appl Environ Microbiol. 1997 Jul;63(7):2802-13 11352068 - Science. 2001 May 11;292(5519):1115-8 19712374 - FEMS Microbiol Ecol. 2004 Oct 1;50(1):25-36 19709182 - FEMS Microbiol Ecol. 2002 Jan 1;39(1):33-9 10940278 - Gut. 2000 Sep;47(3):397-403 12513976 - Appl Environ Microbiol. 2003 Jan;69(1):49-55 16849351 - Gut. 2006 Aug;55(8):1207 8550487 - J Bacteriol. 1996 Feb;178(3):591-9 15168372 - Gastroenterology. 2004 May;126(6):1620-33 15082587 - Gut. 2004 May;53(5):685-93 16000838 - Appl Environ Microbiol. 2005 Jul;71(7):4153-5 12524406 - Gut. 2003 Feb;52(2):237-42 7463489 - J Mol Evol. 1980 Dec;16(2):111-20 11385576 - Nature. 2001 May 31;411(6837):599-603 15001713 - Science. 2004 Apr 2;304(5667):66-74 10742046 - Mol Biol Evol. 2000 Apr;17(4):540-52 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 7984417 - Nucleic Acids Res. 1994 Nov 11;22(22):4673-80
References_xml	– reference: 11385576 - Nature. 2001 May 31;411(6837):599-603 – reference: 7984417 - Nucleic Acids Res. 1994 Nov 11;22(22):4673-80 – reference: 19712374 - FEMS Microbiol Ecol. 2004 Oct 1;50(1):25-36 – reference: 12324374 - Appl Environ Microbiol. 2002 Oct;68(10):5186-90 – reference: 12520046 - Nucleic Acids Res. 2003 Jan 1;31(1):442-3 – reference: 10940278 - Gut. 2000 Sep;47(3):397-403 – reference: 16849351 - Gut. 2006 Aug;55(8):1207 – reference: 8902363 - Comput Appl Biosci. 1996 Aug;12(4):357-8 – reference: 10831436 - Appl Environ Microbiol. 2000 Jun;66(6):2541-7 – reference: 11823207 - Appl Environ Microbiol. 2002 Feb;68(2):673-90 – reference: 11352068 - Science. 2001 May 11;292(5519):1115-8 – reference: 12513976 - Appl Environ Microbiol. 2003 Jan;69(1):49-55 – reference: 10742256 - Appl Environ Microbiol. 2000 Apr;66(4):1654-61 – reference: 10742046 - Mol Biol Evol. 2000 Apr;17(4):540-52 – reference: 15184153 - Appl Environ Microbiol. 2004 Jun;70(6):3528-34 – reference: 15703577 - Curr Opin Gastroenterol. 2003 Jul;19(4):358-65 – reference: 4598229 - Appl Microbiol. 1974 May;27(5):961-79 – reference: 7463489 - J Mol Evol. 1980 Dec;16(2):111-20 – reference: 12363017 - Microbiol Immunol. 2002;46(8):535-48 – reference: 19709182 - FEMS Microbiol Ecol. 2002 Jan 1;39(1):33-9 – reference: 12583961 - Lancet. 2003 Feb 8;361(9356):512-9 – reference: 15001713 - Science. 2004 Apr 2;304(5667):66-74 – reference: 11152940 - FEMS Microbiol Rev. 2001 Jan;25(1):39-67 – reference: 15082587 - Gut. 2004 May;53(5):685-93 – reference: 16000838 - Appl Environ Microbiol. 2005 Jul;71(7):4153-5 – reference: 15168372 - Gastroenterology. 2004 May;126(6):1620-33 – reference: 8550487 - J Bacteriol. 1996 Feb;178(3):591-9 – reference: 10543789 - Appl Environ Microbiol. 1999 Nov;65(11):4799-807 – reference: 14684564 - Gut. 2004 Jan;53(1):1-4 – reference: 9212428 - Appl Environ Microbiol. 1997 Jul;63(7):2802-13 – reference: 12524406 - Gut. 2003 Feb;52(2):237-42
SSID	ssj0008891
Score	2.4742932
Snippet	Background and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn’s disease (CD) is strongly suspected.... A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected. However, investigation of... Background and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected.... BACKGROUND: and aim: A role for the intestinal microbial community (microbiota) in the onset and chronicity of Crohn's disease (CD) is strongly suspected....
SourceID	pubmedcentral hal proquest pubmed pascalfrancis crossref istex bmj
SourceType	Open Access Repository Aggregation Database Index Database Enrichment Source Publisher
StartPage	205
SubjectTerms	Adolescent Adult Bacteria Bacteria - classification Bacteria - genetics Bacteria - isolation & purification Bacterial Typing Techniques Biological and medical sciences Cloning CPL Crohn Disease - microbiology Crohn patient library Crohn's disease Deoxyribonucleic acid DNA DNA, Bacterial - genetics Ecosystem Ecosystems faecal microbiota Feces - microbiology Female Firmicutes FISH fluorescent in situ hybridisation Gastroenterology. Liver. Pancreas. Abdomen Gene Library Genes Genomes healthy subject library HSL Humans IBD In Situ Hybridization, Fluorescence Inflammatory Bowel Disease Life Sciences Male Medical sciences metagenome Microorganisms Molecular weight operational taxonomic unit Other diseases. Semiology OTU PCR Phylogenetics Phylogeny polymerase chain reaction RNA, Bacterial - genetics RNA, Ribosomal, 16S - genetics saline sodium citrate SDS sodium dodecyl sulphate SSC Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Studies
Title	Reduced diversity of faecal microbiota in Crohn’s disease revealed by a metagenomic approach
URI	http://gut.bmj.com/content/55/2/205.full https://api.istex.fr/ark:/67375/NVC-M53D7CJV-1/fulltext.pdf https://www.ncbi.nlm.nih.gov/pubmed/16188921 https://www.proquest.com/docview/1779335330 https://www.proquest.com/docview/19433594 https://www.proquest.com/docview/70682916 https://hal.inrae.fr/hal-02667954 https://pubmed.ncbi.nlm.nih.gov/PMC1856500
Volume	55
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwhV3fb9MwELbYKiFeEL8pjGIBAl7Ckji2kyc0yqZqohWa2NQHJMt2YtqNJqNNEfz33DVOSxGD1_gcJ76zfWd__o6QF45lTAu8HJNKEyQizAJjU4hSkAhaC87jFC84D0dicJocj_nYb7gtPKyynRNXE3VeWdwj348kWBJDLOTby28BZo3C01WfQmOHdJC6DCFdcrwOuBDBE7UzMZdJ5ql9Iib2vyxrv6EikaMOVhYzO99am3YmiIzsYGf_QMSkXkCnuSbbxd_c0T9Rlb8tU0e3yE3vX9KDxiBuk2tFeYdcH_oT9Lvk8wlytRY5zVtABq0cdbqAZuls2tAy1ZpOS9qfV5Py1YL6MxyKZE-wnOTU_KSazopaI8Er1KEtMfk9cnp0-Kk_CHyGhcDwVNYBz7RmTITamTCJQmsTCwPeSJciP2hopNCxM-DBGGG0KKxzDlwIK6woWGy4ZffJblmVxUNCdcKdyEGaG5tkIk15HKZ5AS8xljmju-Q59LC6bDg01Cr2YEKBHjATJleNHrrkTasBZT1JOebK-Hp1hdfrCv999zNQ6VoKebUHBx8UPoNAVMiMJ9-jLnm50vhaTM8vEPsmuRqd9dWQs_eyf3ymQLC3ZRKb1iWE5CwGgb3WRpSfFxZqY8Vd8nRdDCMaj2l0WVRLkMkSEMmSqyVkKNIY_PouedCY3KZxEYHRY-Nyyxi3_nq7pJxOVqzi4LiBtx4--vdnPyY3mk0oBPTskd16viyegFtWm95q7PVI593h6OPJL2tBNSc
linkProvider	ProQuest
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELe2VYK9IL4pjM3i-yUsTfyRPCA0uk3d1lZo2qY9IBnbidcCTUebAvun-Bu5a5KWIgZPe03OduI734d9_h0hz1wYh1rg5ZhIGo8JP_aMjSBKQSBoLTgPIrzg3OmK1jHbP-WnS-RndRcG0yornThV1MnQ4h75ZkOCJIWYC_n2_KuHVaPwdLUqoVGIxUF68R1CtvGbvW3g7_Mg2N05ara8sqqAZ3gkc4_HWoeh8LUzPmv41jILQm6kixAT0zdS6MAZsNpGGC1S65wDs2mFFWkYGG5D6HeZ1Bh0AYqg9m6n-_5wpvujqkYf6H4uWVyCCTVCsXk2ycstHImoeGDLzODTgjVc7mEuZg3Z-wNzNPUY2OSK-hp_c4D_zOP8zTDu3iQ3So-WbhUieIsspdltcq1TntnfIR8OER02TWhSpYDQoaNOpzAsHfQLIKhc035Gm6NhL3s5puWpEUV4KTBgCTUXVNNBmmuElIU2tIJCv0uOr2T275GVbJilDwjVjDuRADU3lsUiinjgR0kKnRgbOqPr5CnMsDovUDvUNNoJhQI-YO1Nrgo-1MnrigPKlrDoWJ3jy-UNXs0a_LfvJ8DSGRUiebe22gqfQegrZMzZt0advJhyfEamR58x205y1T1pqg4Pt2Vz_0QB4fqCSMxHlww8rwAI1ioZUaUmGqv5uqmTjdlr0CF4MKSzdDgBmpgBScwup5C-iAKIJOrkfiFy88FFA4QeB5cLwrjw14tvsn5vimMOriLEB_7Df3_2BrneOuq0VXuve_CIrBZbYJhOtEZW8tEkfQxOYW7Wy5VIycerXvy_AP38co4
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Lj9MwELb2Ia24IN4Ull2L9yU0iWM7OSC0aqm6j1YIsasekIztxLRA06XNAvvX-HXMNElLEQunvTZju8nMeDz2528IeexYwrTAyzGxNF4k_MQzNoYsBYmgteA8jPGCc68vusfRwYAP1sjP-i4MwirrOXE-UacTi3vkzUCCJTHEQjZdBYt40-68Ov3qYQUpPGmty2mUJnKYnX-H9G32cr8Nun4Shp3X71pdr6ow4Bkey8LjidaMCV8740eBb21kweCNdDHyY_pGCh06AxHcCKNFZp1zEEKtsCJjoeGWQb_rZFMyHqCPycEi2UP0UFBHAS6jpKIVCphofjwrqs0cifx4ENXM-NNKXFwfIipzExX9A9GaegYKc2Wljb8thf9EdP4WIjvXyNVqbUv3SmO8Ttay_AbZ6lWn9zfJ-7fIE5ulNK3BIHTiqNMZDEvHo5ISqtB0lNPWdDLMn81odX5EkWgKQllKzTnVdJwVGslloQ2tSdFvkeNL-fa3yUY-ybO7hOqIO5GCNDc2SkQc89CP0ww6MZY5oxvkEXxhdVryd6h53sOEAj1gFU6uSj00yItaA8pWBOlYp-PLxQ2eLxr8t--HoNKFFHJ6d_eOFP4GSbCQCY--BQ3ydK7xhZiefkbcneSqf9JSPc7asnVwokBwZ8UklqPLCNZgIQhs1zaiqjlpppYe1CC7i8cwm-ARkc6zyRnIJBGIJNHFEtIXcQg5RYPcKU1uObgIwOhxcLlijCtvvfokHw3njOawaIRMwb_377-9S7bA5dXRfv_wPrlS7oUhrmibbBTTs-wBrA4LszN3Q0o-XLbf_wIhUHVe
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Reduced+diversity+of+faecal+microbiota+in+Crohn%27s+disease+revealed+by+a+metagenomic+approach&rft.jtitle=Gut&rft.au=Manichanh%2C+C&rft.au=Rigottier-Gois%2C+L&rft.au=Bonnaud%2C+E&rft.au=Gloux%2C+K&rft.date=2006-02-01&rft.pub=BMJ+Publishing+Group+LTD&rft.issn=0017-5749&rft.eissn=1468-3288&rft.volume=55&rft.issue=2&rft.spage=205&rft_id=info:doi/10.1136%2Fgut.2005.073817&rft.externalDBID=HAS_PDF_LINK&rft.externalDocID=4014170481
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0017-5749&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0017-5749&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0017-5749&client=summon