Prediction of response to PPI therapy and factors influencing treatment outcome in patients with GORD: a prospective pragmatic trial using pantoprazole

• Published in: BMC gastroenterology Vol. 11; no. 1; p. 52
• Main Authors: Heading, Robert C, Mönnikes, Hubert, Tholen, Anne, Schmitt, Holger
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 11.05.2011; BioMed Central; BMC
• Subjects: 2-Pyridinylmethylsulfinylbenzimidazoles - adverse effects; 2-Pyridinylmethylsulfinylbenzimidazoles - therapeutic use; Adult; Anxiety; Body Mass Index; Dosage and administration; Drug therapy; Female; Gastroesophageal reflux; Gastroesophageal Reflux - drug therapy; Gastroesophageal Reflux - pathology; Humans; Irritable Bowel Syndrome; Logistic Models; Male; Middle Aged; Pantoprazole; Patient outcomes; Patient Satisfaction; Proton Pump Inhibitors - adverse effects; Proton Pump Inhibitors - therapeutic use; Quality of Life; Sex Factors; Surveys and Questionnaires; Treatment Outcome; United Kingdom; Switzerland; Germany

Management of patients with gastro-oesophageal reflux disease (GORD) can be assisted by information predicting the likely response to proton pump inhibitor (PPI) treatment. The aim was to undertake a study of GORD patients designed to approximate ordinary clinical practice that would identify patien...