Designing the next generation of medicines for malaria control and eradication

• Published in: Malaria journal Vol. 12; no. 1; p. 187
• Main Authors: Burrows, Jeremy N, van Huijsduijnen, Rob Hooft, Möhrle, Jörg J, Oeuvray, Claude, Wells, Timothy N C
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 06.06.2013; BioMed Central
• Subjects: Anopheles; Antimalarials - isolation & purification; Antimalarials - pharmacokinetics; Antimalarials - pharmacology; Antimalarials - therapeutic use; Dihydrofolate reductase; Disease prevention; Drug discovery; Drug Discovery - methods; Drug Discovery - trends; Drug dosages; Drug Resistance; Drug Stability; Drug Therapy, Combination - methods; Drugs; Humans; Infections; Malaria; Malaria - drug therapy; Malaria - prevention & control; Parasites; Patients; Pharmaceutical industry; Prevention; Public health; Review; Tuberculosis; Vaccines; Switzerland

In the fight against malaria new medicines are an essential weapon. For the parts of the world where the current gold standard artemisinin combination therapies are active, significant improvements can still be made: for example combination medicines which allow for single dose regimens, cheaper, sa...