Optimization of [11C]methionine PET study: appropriate scan timing and effect of plasma amino acid concentrations on the SUV

• Published in: EJNMMI research Vol. 3; no. 1; pp. 27 - 7
• Main Authors: Isohashi, Kayako, Shimosegawa, Eku, Kato, Hiroki, Kanai, Yasukazu, Naka, Sadahiro, Fujino, Koichi, Watabe, Hiroshi, Hatazawa, Jun
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 15.04.2013; Springer Nature B.V; BioMed Central Ltd; Springer
• Subjects: Cardiac Imaging; Imaging; Medicine; Medicine & Public Health; Nuclear Medicine; Oncology; Original Research; Orthopedics; Radiology; Normal volunteers; PET; Methionine; Plasma concentrations of neutral amino acids
• ISSN: 2191-219X; 2191-219X
• DOI: 10.1186/2191-219X-3-27

Background [ 11 C]methionine (MET) has been used to monitor amino acid metabolism in tumors, the pancreas, liver, and myocardium. The aim of the present study was to standardize [ 11 C]MET positron emission tomography (PET) by optimizing the timing of initiation of the scan and applying correction t...