Influenza vaccines licensed in the United States in healthy children: a systematic review and network meta-analysis (Protocol)
Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence suppor...
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Published in | Systematic reviews Vol. 1; no. 1; p. 65 |
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Main Authors | , , , , , , , |
Format | Journal Article |
Language | English |
Published |
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BioMed Central Ltd
29.12.2012
BioMed Central BMC |
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Abstract | Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence supporting the decision of which of available vaccines to use remains unclear.This review will summarize the evidence about the efficacy and safety of the available vaccines for seasonal influenza licensed in the United States for use in healthy children.
An umbrella systematic review (SR) and network meta-analysis will be conducted of randomized controlled trials (RCTs). We will search for SRs to identify parallel RCTs evaluating inactive and/or live attenuated influenza vaccines licensed in the United States for use in healthy children to prevent influenza. Subsequently, we will update the literature search of the selected SRs to the present time to capture recent controlled studies. To complement the work focused on harms, we will also select observational studies focusing on post marketing retrospective studies. Inclusion will not be limited by language, publication date or publication status. To identify additional candidate studies, we will review the reference lists of the eligible primary studies and narrative reviews; we will query the expert members of the Advisory Committee on Immunization Practices and review references from their previous statement. Additionally, we will review the reports from the Institute of Medicine on the adverse effects of vaccines. Two reviewers will independently determine study eligibility and will extract descriptive, methodological (using the Cochrane risk of bias tool for RCTs and the Newcastle-Ottawa scale for observational studies) and efficacy data. When possible, we will conduct meta-analyses and network meta-analyses by combining indirect and direct comparisons.We will evaluate heterogeneity using the I2 statistic and the agreement of indirect comparisons and direct evidence. We will report the Cochrane Q test to determine the statistical significance of heterogeneity.The overall quality of evidence will be assessed following the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) approach.
Our systematic review will allow patients, clinicians, guideline developers and policy makers to make evidence-based choices between the two available vaccine options, by providing information regarding benefits and harms of these types of vaccines. |
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AbstractList | UNLABELLED BACKGROUNDInfluenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence supporting the decision of which of available vaccines to use remains unclear.This review will summarize the evidence about the efficacy and safety of the available vaccines for seasonal influenza licensed in the United States for use in healthy children. METHODS/DESIGNAn umbrella systematic review (SR) and network meta-analysis will be conducted of randomized controlled trials (RCTs). We will search for SRs to identify parallel RCTs evaluating inactive and/or live attenuated influenza vaccines licensed in the United States for use in healthy children to prevent influenza. Subsequently, we will update the literature search of the selected SRs to the present time to capture recent controlled studies. To complement the work focused on harms, we will also select observational studies focusing on post marketing retrospective studies. Inclusion will not be limited by language, publication date or publication status. To identify additional candidate studies, we will review the reference lists of the eligible primary studies and narrative reviews; we will query the expert members of the Advisory Committee on Immunization Practices and review references from their previous statement. Additionally, we will review the reports from the Institute of Medicine on the adverse effects of vaccines. Two reviewers will independently determine study eligibility and will extract descriptive, methodological (using the Cochrane risk of bias tool for RCTs and the Newcastle-Ottawa scale for observational studies) and efficacy data. When possible, we will conduct meta-analyses and network meta-analyses by combining indirect and direct comparisons.We will evaluate heterogeneity using the I2 statistic and the agreement of indirect comparisons and direct evidence. We will report the Cochrane Q test to determine the statistical significance of heterogeneity.The overall quality of evidence will be assessed following the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) approach. DISCUSSIONOur systematic review will allow patients, clinicians, guideline developers and policy makers to make evidence-based choices between the two available vaccine options, by providing information regarding benefits and harms of these types of vaccines. Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence supporting the decision of which of available vaccines to use remains unclear.This review will summarize the evidence about the efficacy and safety of the available vaccines for seasonal influenza licensed in the United States for use in healthy children. An umbrella systematic review (SR) and network meta-analysis will be conducted of randomized controlled trials (RCTs). We will search for SRs to identify parallel RCTs evaluating inactive and/or live attenuated influenza vaccines licensed in the United States for use in healthy children to prevent influenza. Subsequently, we will update the literature search of the selected SRs to the present time to capture recent controlled studies. To complement the work focused on harms, we will also select observational studies focusing on post marketing retrospective studies. Inclusion will not be limited by language, publication date or publication status. To identify additional candidate studies, we will review the reference lists of the eligible primary studies and narrative reviews; we will query the expert members of the Advisory Committee on Immunization Practices and review references from their previous statement. Additionally, we will review the reports from the Institute of Medicine on the adverse effects of vaccines. Two reviewers will independently determine study eligibility and will extract descriptive, methodological (using the Cochrane risk of bias tool for RCTs and the Newcastle-Ottawa scale for observational studies) and efficacy data. When possible, we will conduct meta-analyses and network meta-analyses by combining indirect and direct comparisons.We will evaluate heterogeneity using the I2 statistic and the agreement of indirect comparisons and direct evidence. We will report the Cochrane Q test to determine the statistical significance of heterogeneity.The overall quality of evidence will be assessed following the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) approach. Our systematic review will allow patients, clinicians, guideline developers and policy makers to make evidence-based choices between the two available vaccine options, by providing information regarding benefits and harms of these types of vaccines. Abstract Background Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence supporting the decision of which of available vaccines to use remains unclear. This review will summarize the evidence about the efficacy and safety of the available vaccines for seasonal influenza licensed in the United States for use in healthy children. Methods/design An umbrella systematic review (SR) and network meta-analysis will be conducted of randomized controlled trials (RCTs). We will search for SRs to identify parallel RCTs evaluating inactive and/or live attenuated influenza vaccines licensed in the United States for use in healthy children to prevent influenza. Subsequently, we will update the literature search of the selected SRs to the present time to capture recent controlled studies. To complement the work focused on harms, we will also select observational studies focusing on post marketing retrospective studies. Inclusion will not be limited by language, publication date or publication status. To identify additional candidate studies, we will review the reference lists of the eligible primary studies and narrative reviews; we will query the expert members of the Advisory Committee on Immunization Practices and review references from their previous statement. Additionally, we will review the reports from the Institute of Medicine on the adverse effects of vaccines. Two reviewers will independently determine study eligibility and will extract descriptive, methodological (using the Cochrane risk of bias tool for RCTs and the Newcastle–Ottawa scale for observational studies) and efficacy data. When possible, we will conduct meta-analyses and network meta-analyses by combining indirect and direct comparisons. We will evaluate heterogeneity using the I2 statistic and the agreement of indirect comparisons and direct evidence. We will report the Cochrane Q test to determine the statistical significance of heterogeneity. The overall quality of evidence will be assessed following the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) approach. Discussion Our systematic review will allow patients, clinicians, guideline developers and policy makers to make evidence-based choices between the two available vaccine options, by providing information regarding benefits and harms of these types of vaccines. BACKGROUND: Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for prevention methods, including vaccination. While evidence about the decision on whether to vaccinate healthy children is robust, evidence supporting the decision of which of available vaccines to use remains unclear.This review will summarize the evidence about the efficacy and safety of the available vaccines for seasonal influenza licensed in the United States for use in healthy children. METHODS/DESIGN: An umbrella systematic review (SR) and network meta-analysis will be conducted of randomized controlled trials (RCTs). We will search for SRs to identify parallel RCTs evaluating inactive and/or live attenuated influenza vaccines licensed in the United States for use in healthy children to prevent influenza. Subsequently, we will update the literature search of the selected SRs to the present time to capture recent controlled studies. To complement the work focused on harms, we will also select observational studies focusing on post marketing retrospective studies. Inclusion will not be limited by language, publication date or publication status. To identify additional candidate studies, we will review the reference lists of the eligible primary studies and narrative reviews; we will query the expert members of the Advisory Committee on Immunization Practices and review references from their previous statement. Additionally, we will review the reports from the Institute of Medicine on the adverse effects of vaccines. Two reviewers will independently determine study eligibility and will extract descriptive, methodological (using the Cochrane risk of bias tool for RCTs and the Newcastle-Ottawa scale for observational studies) and efficacy data. When possible, we will conduct meta-analyses and network meta-analyses by combining indirect and direct comparisons.We will evaluate heterogeneity using the I2 statistic and the agreement of indirect comparisons and direct evidence. We will report the Cochrane Q test to determine the statistical significance of heterogeneity.The overall quality of evidence will be assessed following the GRADE (Grading of Recommendation, Assessment, Development and Evaluation) approach. DISCUSSION: Our systematic review will allow patients, clinicians, guideline developers and policy makers to make evidence-based choices between the two available vaccine options, by providing information regarding benefits and harms of these types of vaccines. |
ArticleNumber | 65 |
Author | Elraiyah, Tarig Wang, Zhen Montori, Victor M Grohskopf, Lisa A Prutsky, Gabriela J Murad, Mohammad Hassan Domecq, Juan Pablo Prokop, Larry J |
AuthorAffiliation | 2 Unidad de Conocimiento y Evidencia (CONEVID), Universidad Peruana Cayetano Heredia, 430 Honorio Delgado Ave, San Martin de Porres, Lima 31, Peru 4 Division of Endocrinology, Diabetes, Metabolism, Nutrition, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA 3 Division of Preventive, Occupational and Aerospace Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA 1 Knowledge and Evaluation Research Unit (KER), Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA 5 Mayo Clinic Libraries, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA 6 Influenza Division, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA, 30333, USA |
AuthorAffiliation_xml | – name: 4 Division of Endocrinology, Diabetes, Metabolism, Nutrition, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA – name: 3 Division of Preventive, Occupational and Aerospace Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA – name: 5 Mayo Clinic Libraries, Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA – name: 1 Knowledge and Evaluation Research Unit (KER), Mayo Clinic, 200 First Street SW, Rochester, MN, 55905, USA – name: 6 Influenza Division, Centers for Disease Control and Prevention (CDC), 1600 Clifton Road, Atlanta, GA, 30333, USA – name: 2 Unidad de Conocimiento y Evidencia (CONEVID), Universidad Peruana Cayetano Heredia, 430 Honorio Delgado Ave, San Martin de Porres, Lima 31, Peru |
Author_xml | – sequence: 1 givenname: Gabriela J surname: Prutsky fullname: Prutsky, Gabriela J email: prutskylopez.gabriela@mayo.edu organization: Knowledge and Evaluation Research Unit (KER), Mayo Clinic, 200 First Street S.W., Rochester, MN 55905, USA. prutskylopez.gabriela@mayo.edu – sequence: 2 givenname: Juan Pablo surname: Domecq fullname: Domecq, Juan Pablo – sequence: 3 givenname: Tarig surname: Elraiyah fullname: Elraiyah, Tarig – sequence: 4 givenname: Zhen surname: Wang fullname: Wang, Zhen – sequence: 5 givenname: Lisa A surname: Grohskopf fullname: Grohskopf, Lisa A – sequence: 6 givenname: Larry J surname: Prokop fullname: Prokop, Larry J – sequence: 7 givenname: Victor M surname: Montori fullname: Montori, Victor M – sequence: 8 givenname: Mohammad Hassan surname: Murad fullname: Murad, Mohammad Hassan |
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Cites_doi | 10.1136/bmj.327.7414.557 10.1542/peds.2011-0737C 10.1056/NEJMoa054869 10.1186/1471-2288-7-10 10.1016/j.jclinepi.2009.06.006 10.1001/jama.292.11.1333 10.1007/s00345-011-0667-2 10.3310/hta9260 10.1016/j.vaccine.2012.02.041 10.1016/j.jval.2011.01.011 10.1097/01.inf.0000092188.48726.e4 10.1093/aje/kwp345 10.1001/jama.295.6.676 10.1016/S1526-0542(03)00027-7 10.1186/1471-2288-11-15 10.1016/j.jclinepi.2011.06.004 10.1542/peds.2011-2295 10.1002/14651858.CD004879.pub3 10.1002/0470854200.ch4 10.1002/jrsm.30 10.1002/sim.1201 |
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References | 15367555 - JAMA. 2004 Sep 15;292(11):1333-40 21387101 - World J Urol. 2011 Jun;29(3):311-7 12758046 - Paediatr Respir Rev. 2003 Jun;4(2):99-104 21291558 - BMC Med Res Methodol. 2011;11(1):15 17302989 - BMC Med Res Methodol. 2007;7:10 11760981 - CMAJ. 2001 Nov 13;165(10):1339-41 21866086 - MMWR Morb Mortal Wkly Rep. 2011 Aug 26;60(33):1128-32 21802902 - J Clin Epidemiol. 2011 Dec;64(12):1311-6 16822994 - N Engl J Med. 2006 Jul 6;355(1):31-40 20689501 - MMWR Recomm Rep. 2010 Aug 6;59(RR-8):1-62 20798667 - MMWR Morb Mortal Wkly Rep. 2010 Aug 27;59(33):1057-62 16467236 - JAMA. 2006 Feb 8;295(6):676-80 19631507 - J Clin Epidemiol. 2009 Oct;62(10):e1-34 22383482 - Pediatrics. 2012 Mar;129 Suppl 2:S54-62 14551476 - Pediatr Infect Dis J. 2003 Oct;22(10 Suppl):S207-10 19965887 - Am J Epidemiol. 2010 Jan 15;171(2):177-88 16014203 - Health Technol Assess. 2005 Jul;9(26):1-134, iii-iv 21669367 - Value Health. 2011 Jun;14(4):429-37 21890834 - Pediatrics. 2011 Oct;128(4):813-25 22391401 - Vaccine. 2012 Dec 17;31(1):12-9 12210616 - Stat Med. 2002 Aug 30;21(16):2313-24 18425905 - Cochrane Database Syst Rev. 2008;(2):CD004879 26061466 - Res Synth Methods. 2010 Jul;1(3-4):198-211 12958120 - BMJ. 2003 Sep 6;327(7414):557-60 KFA Stratton (55_CR15) 2011 GH Guyatt (55_CR28) 2011; 64 WW Thompson (55_CR2) 2004; 292 AM Glenny (55_CR22) 2005; 9 American Academy of Pediatrics Committee on Infectious Diseases (55_CR9) 2011; 128 J Higgins (55_CR17) 2011 V Smith (55_CR10) 2011; 11 Centers for Disease Control and Prevention (CDC) (55_CR1) 2010; 59 A Liberati (55_CR25) 2009; 62 SE Canfield (55_CR27) 2011; 29 FM Munoz (55_CR4) 2003; 4 P Duclos (55_CR29) 2012; 31 N Principi (55_CR6) 2003; 22 JL Peters (55_CR24) 2006; 295 SK Greene (55_CR16) 2010; 171 A Whitehead (55_CR19) 2002 JP Higgins (55_CR20) 2003; 327 R Jaeschke (55_CR18) 2008 KA Poehling (55_CR3) 2006; 355 AE Fiore (55_CR5) 2010; 59 DC Hoaglin (55_CR26) 2011; 14 T Lumley (55_CR21) 2002; 21 VM Montori (55_CR23) 2001; 165 DRK Thomson (55_CR11) 2011; 1 Centers for Disease Control and Prevention (CDC) (55_CR8) 2011; 60 AE Fiore (55_CR7) 2012; 129 BJ Shea (55_CR12) 2007; 7 KAD Stratton (55_CR13) 2004 Program CotRotNIPsRPaDS (55_CR14) 2005 55_CR30 |
References_xml | – volume: 327 start-page: 557 year: 2003 ident: 55_CR20 publication-title: BMJ doi: 10.1136/bmj.327.7414.557 contributor: fullname: JP Higgins – volume: 129 start-page: S54 issue: Suppl 2 year: 2012 ident: 55_CR7 publication-title: Pediatrics doi: 10.1542/peds.2011-0737C contributor: fullname: AE Fiore – volume: 355 start-page: 31 year: 2006 ident: 55_CR3 publication-title: N Engl J Med doi: 10.1056/NEJMoa054869 contributor: fullname: KA Poehling – volume: 7 start-page: 10 year: 2007 ident: 55_CR12 publication-title: BMC Med Res Methodol doi: 10.1186/1471-2288-7-10 contributor: fullname: BJ Shea – volume: 62 start-page: e1 year: 2009 ident: 55_CR25 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2009.06.006 contributor: fullname: A Liberati – volume: 292 start-page: 1333 year: 2004 ident: 55_CR2 publication-title: JAMA doi: 10.1001/jama.292.11.1333 contributor: fullname: WW Thompson – volume: 29 start-page: 311 year: 2011 ident: 55_CR27 publication-title: World J Urol doi: 10.1007/s00345-011-0667-2 contributor: fullname: SE Canfield – volume-title: Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0 [updated March 2011] year: 2011 ident: 55_CR17 contributor: fullname: J Higgins – volume: 60 start-page: 1128 year: 2011 ident: 55_CR8 publication-title: MMWR Morb Mortal Wkly Rep contributor: fullname: Centers for Disease Control and Prevention (CDC) – volume: 9 start-page: 1 year: 2005 ident: 55_CR22 publication-title: Health Technol Assess doi: 10.3310/hta9260 contributor: fullname: AM Glenny – volume: 31 start-page: 12 year: 2012 ident: 55_CR29 publication-title: Vaccine doi: 10.1016/j.vaccine.2012.02.041 contributor: fullname: P Duclos – volume: 14 start-page: 429 year: 2011 ident: 55_CR26 publication-title: Value Health doi: 10.1016/j.jval.2011.01.011 contributor: fullname: DC Hoaglin – volume: 22 start-page: S207 year: 2003 ident: 55_CR6 publication-title: Pediatr Infect Dis J doi: 10.1097/01.inf.0000092188.48726.e4 contributor: fullname: N Principi – volume: 171 start-page: 177 year: 2010 ident: 55_CR16 publication-title: Am J Epidemiol doi: 10.1093/aje/kwp345 contributor: fullname: SK Greene – volume-title: Adverse Effects of Vaccines: Evidence and Causality year: 2011 ident: 55_CR15 contributor: fullname: KFA Stratton – volume: 295 start-page: 676 year: 2006 ident: 55_CR24 publication-title: JAMA doi: 10.1001/jama.295.6.676 contributor: fullname: JL Peters – volume: 165 start-page: 1339 year: 2001 ident: 55_CR23 publication-title: CMAJ contributor: fullname: VM Montori – volume: 4 start-page: 99 year: 2003 ident: 55_CR4 publication-title: Paediatr Respir Rev doi: 10.1016/S1526-0542(03)00027-7 contributor: fullname: FM Munoz – volume: 59 start-page: 1 year: 2010 ident: 55_CR5 publication-title: MMWR Recomm Rep contributor: fullname: AE Fiore – volume: 11 start-page: 15 year: 2011 ident: 55_CR10 publication-title: BMC Med Res Methodol doi: 10.1186/1471-2288-11-15 contributor: fullname: V Smith – volume: 59 start-page: 1057 year: 2010 ident: 55_CR1 publication-title: MMWR Morb Mortal Wkly Rep contributor: fullname: Centers for Disease Control and Prevention (CDC) – start-page: 221 volume-title: User’s Guides to the Medical Literature: A Manual for Evidence-Based Clinical Practice year: 2008 ident: 55_CR18 contributor: fullname: R Jaeschke – volume-title: Immunization Safety Review: Influenza Vaccine and Neurologic Complications year: 2004 ident: 55_CR13 contributor: fullname: KAD Stratton – volume: 64 start-page: 1311 year: 2011 ident: 55_CR28 publication-title: J Clin Epidemiol doi: 10.1016/j.jclinepi.2011.06.004 contributor: fullname: GH Guyatt – volume: 128 start-page: 813 year: 2011 ident: 55_CR9 publication-title: Pediatrics doi: 10.1542/peds.2011-2295 contributor: fullname: American Academy of Pediatrics Committee on Infectious Diseases – ident: 55_CR30 doi: 10.1002/14651858.CD004879.pub3 – volume-title: Vaccine Safety Research, Data Access, and Public Trust year: 2005 ident: 55_CR14 contributor: fullname: Program CotRotNIPsRPaDS – start-page: 57 volume-title: Meta-analysis of controlled clinical trials, Volume 23 year: 2002 ident: 55_CR19 doi: 10.1002/0470854200.ch4 contributor: fullname: A Whitehead – volume: 1 start-page: 198 year: 2011 ident: 55_CR11 publication-title: Research Synthesis Methods doi: 10.1002/jrsm.30 contributor: fullname: DRK Thomson – volume: 21 start-page: 2313 year: 2002 ident: 55_CR21 publication-title: Stat Med doi: 10.1002/sim.1201 contributor: fullname: T Lumley |
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Snippet | Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important target for... UNLABELLED BACKGROUNDInfluenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an... BACKGROUND: Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an important... Abstract Background Influenza is an acute respiratory illness caused by influenza viruses, which occurs in epidemics worldwide every year. Children are an... |
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SubjectTerms | Child Children Humans Influenza Influenza vaccine Influenza Vaccines Influenza, Human - prevention & control Meta-Analysis as Topic Protocol Research Design Review Literature as Topic Systematic review United States - epidemiology |
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Title | Influenza vaccines licensed in the United States in healthy children: a systematic review and network meta-analysis (Protocol) |
URI | https://www.ncbi.nlm.nih.gov/pubmed/23272706 https://search.proquest.com/docview/1273260311 http://dx.doi.org/10.1186/2046-4053-1-65 https://pubmed.ncbi.nlm.nih.gov/PMC3537683 https://doaj.org/article/bab758aaf0f54b49892bbe3eb079bcaa |
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