Coronary heart disease after prenatal exposure to the Dutch famine, 1944–45

• Published in: Heart (British Cardiac Society) Vol. 84; no. 6; pp. 595 - 598
• Main Authors: Roseboom, T J, van der Meulen, J H P, Osmond, C, Barker, D J P, Ravelli, A C J, Schroeder-Tanka, J M, van Montfrans, G A, Michels, R P J, Bleker, O P
• Format: Journal Article
• Language: English
• Published: London BMJ Publishing Group Ltd and British Cardiovascular Society 01.12.2000; BMJ; BMJ Publishing Group LTD
• Subjects: Angina pectoris; Biological and medical sciences; Birth Weight; Cardiology. Vascular system; Cardiovascular disease; Cardiovascular Medicine; Cephalometry; Cohort Studies; Coronary Disease - embryology; Coronary Disease - epidemiology; Coronary heart disease; Famine; Female; fetal origins hypothesis; Gestational Age; Health risk assessment; Heart; Humans; Infant, Newborn; Male; maternal malnutrition; Medical sciences; Middle Aged; Mortality; Netherlands - epidemiology; Placental Insufficiency - complications; Pregnancy; Pregnancy Complications; Prenatal exposure; Prenatal Exposure Delayed Effects; Prevalence; Risk Factors; Starvation - complications; Womens health; Netherlands; Europe; Human; Prenatal; Famine; Mother; Risk factor; Cardiovascular disease; Malnutrition; Coronary heart disease

OBJECTIVE To assess the effect of prenatal exposure to maternal malnutrition on coronary heart disease in people born around the time of the Dutch famine, 1944–45. DESIGN Historical cohort study. SETTING Community study. PATIENTS Singletons born alive between November 1943 and February 1947 for whom...