Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City
ObjectiveThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-...
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Published in | BMJ open Vol. 10; no. 11; p. e040736 |
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Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
British Medical Journal Publishing Group
27.11.2020
BMJ Publishing Group LTD BMJ Publishing Group |
Series | Original research |
Subjects | |
Online Access | Get full text |
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Abstract | ObjectiveThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive.DesignDemographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive.SettingAll patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system.ParticipantsParticipants over the age of 18 years were included.Primary outcomesWe investigated in-hospital mortality during the study period.ResultsA total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL.ConclusionsIn our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged. |
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AbstractList | ObjectiveThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive.DesignDemographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive.SettingAll patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system.ParticipantsParticipants over the age of 18 years were included.Primary outcomesWe investigated in-hospital mortality during the study period.ResultsA total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL.ConclusionsIn our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged. The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive.OBJECTIVEThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive.Demographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive.DESIGNDemographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive.All patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system.SETTINGAll patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system.Participants over the age of 18 years were included.PARTICIPANTSParticipants over the age of 18 years were included.We investigated in-hospital mortality during the study period.PRIMARY OUTCOMESWe investigated in-hospital mortality during the study period.A total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL.RESULTSA total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL.In our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged.CONCLUSIONSIn our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged. Objective The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive.Design Demographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive.Setting All patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system.Participants Participants over the age of 18 years were included.Primary outcomes We investigated in-hospital mortality during the study period.Results A total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL.Conclusions In our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged. The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course of hospitalised patients, particularly in the USA. We aimed to compare clinical characteristic of patients with COVID-19 who had in-hospital mortality with those who were discharged alive. Demographic, clinical and outcomes data for patients admitted to five Mount Sinai Health System hospitals with confirmed COVID-19 between 27 February and 2 April 2020 were identified through institutional electronic health records. We performed a retrospective comparative analysis of patients who had in-hospital mortality or were discharged alive. All patients were admitted to the Mount Sinai Health System, a large quaternary care urban hospital system. Participants over the age of 18 years were included. We investigated in-hospital mortality during the study period. A total of 2199 patients with COVID-19 were hospitalised during the study period. As of 2 April, 1121 (51%) patients remained hospitalised, and 1078 (49%) completed their hospital course. Of the latter, the overall mortality was 29%, and 36% required intensive care. The median age was 65 years overall and 75 years in those who died. Pre-existing conditions were present in 65% of those who died and 46% of those discharged. In those who died, the admission median lymphocyte percentage was 11.7%, D-dimer was 2.4 μg/mL, C reactive protein was 162 mg/L and procalcitonin was 0.44 ng/mL. In those discharged, the admission median lymphocyte percentage was 16.6%, D-dimer was 0.93 μg/mL, C reactive protein was 79 mg/L and procalcitonin was 0.09 ng/mL. In our cohort of hospitalised patients, requirement of intensive care and mortality were high. Patients who died typically had more pre-existing conditions and greater perturbations in inflammatory markers as compared with those who were discharged. |
Author | Russak, Adam J Vaid, Akhil Nangia, Udit Narula, Jagat Kapoor, Arjun Fuster, V Just, Allan Bagiella, Emilia Charney, Dennis Levin, Matthew A Kia, Arash Danieletto, Matteo Paranjpe, Ishan Bottinger, Erwin P Charney, Alexander W Fayad, Zahi A Miotto, Riccardo Meyer, Dara De Freitas, Jessica K Kovatch, Patricia Johnson, Kipp W Cordon-Cardo, Carlos Golden, Eddye Horowitz, Carol R Somani, Sulaiman Freeman, Robert M Huckins, Laura M Jhang, Jeffrey Nadkarni, Girish N O’Reilly, Paul Nestler, Eric J Glowe, Patricia Finkelstein, Joseph Reich, David L O'Hagan, Ross Timsina, Prem Firpo, Adolfo Manna, Sayan Jaladanki, Suraj K Aberg, Judith A Murphy, Barbara Lala, Anuradha Singh, Manbir Glicksberg, Benjamin S |
AuthorAffiliation | 2 Department of Internal Medicine , Icahn School of Medicine at Mount Sinai , New York , New York , USA 10 Mount Sinai Data Warehouse , Mount Sinai Health System , New York , New York , USA 23 Institute for Exposomic Research , Icahn School of Medicine at Mount Sinai , New York , New York , USA 1 The Hasso Plattner Institute for Digital Health at Mount Sinai , New York , New York , USA 14 Department of Radiology , Icahn School of Medicine at Mount Sinai , New York , New York , USA 3 Department of Genetics and Genomic Sciences , Icahn School of Medicine at Mount Sinai , New York , New York , USA 24 The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai , New York , New York , USA 13 Icahn School of Medicine at Mount Sinai BioMedical Engineering and Imaging Institute , New York , New York , USA 22 Icahn School of Medicine at Mount Sinai Department of Environmental Medicine and Public Health , New York , New York , USA 4 The Zena and Michael A. Wiener Car |
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organization: Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 27 givenname: Patricia surname: Kovatch fullname: Kovatch, Patricia organization: Mount Sinai Data Warehouse, Mount Sinai Health System, New York, New York, USA – sequence: 28 givenname: Joseph surname: Finkelstein fullname: Finkelstein, Joseph organization: Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 29 givenname: Judith A surname: Aberg fullname: Aberg, Judith A organization: Icahn School of Medicine at Mount Sinai Department of Medicine, New York, New York, USA – sequence: 30 givenname: Emilia surname: Bagiella fullname: Bagiella, Emilia organization: Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 31 givenname: Carol R surname: Horowitz fullname: Horowitz, Carol R organization: Icahn School of Medicine at Mount Sinai Department of Medicine, New York, New York, USA – sequence: 32 givenname: Barbara surname: Murphy fullname: Murphy, Barbara organization: Icahn School of Medicine at Mount Sinai Department of Medicine, New York, New York, USA – sequence: 33 givenname: Zahi A surname: Fayad fullname: Fayad, Zahi A organization: Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 34 givenname: Jagat surname: Narula fullname: Narula, Jagat organization: Department of Cardiology, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 35 givenname: Eric J surname: Nestler fullname: Nestler, Eric J organization: The Nash Family Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York, USA – sequence: 36 givenname: V surname: Fuster fullname: Fuster, V organization: Department of Medicine, Division of Cardiology, Zena and Michael A. 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BackLink | https://www.ncbi.nlm.nih.gov/pubmed/33247020$$D View this record in MEDLINE/PubMed |
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Copyright | Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2020 Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. http://creativecommons.org/licenses/by-nc/4.0/ This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. 2020 |
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CorporateAuthor | Mount Sinai COVID Informatics Center (MSCIC) |
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Studies Needed publication-title: N Engl J Med doi: 10.1056/NEJMp2002125 – volume: 382 start-page: 1708 year: 2020 article-title: Clinical characteristics of coronavirus disease 2019 in China publication-title: N Engl J Med doi: 10.1056/NEJMoa2002032 – volume: 76 start-page: 533 year: 2020 article-title: Prevalence and impact of myocardial injury in patients hospitalized with COVID-19 infection publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2020.06.007 – volume: 77 start-page: 198 year: 2020 article-title: Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction publication-title: Histopathology doi: 10.1111/his.14134 – volume: 382 start-page: 2005 year: 2020 article-title: Epidemiology of Covid-19 in a long-term care facility in King County, Washington publication-title: N Engl J Med doi: 10.1056/NEJMoa2005412 – volume: 323 start-page: 1612 year: 2020 article-title: Characteristics and outcomes of 21 critically ill patients with COVID-19 in Washington state publication-title: JAMA doi: 10.1001/jama.2020.4326 – volume: 323 start-page: 1574 year: 2020 article-title: Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy publication-title: JAMA doi: 10.1001/jama.2020.5394 – volume: 8 start-page: 475 year: 2020 article-title: Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study publication-title: Lancet Respir Med doi: 10.1016/S2213-2600(20)30079-5 – volume: 26 start-page: 1017 year: 2020 article-title: Extrapulmonary manifestations of COVID-19 publication-title: Nat Med doi: 10.1038/s41591-020-0968-3 – volume: 395 start-page: 1 year: 2020 article-title: Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 publication-title: J Thromb Thrombolysis doi: 10.1007/s11239-020-02105-8 – volume: 31 start-page: 2145 year: 2020 article-title: Aki in hospitalized patients with and without COVID-19: a comparison study publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2020040509 – volume: 172 start-page: 577 year: 2020 article-title: The incubation period of coronavirus disease 2019 (COVID-19) from publicly reported confirmed cases: estimation and application publication-title: Ann Intern Med doi: 10.7326/M20-0504 – year: 2020 article-title: Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy publication-title: Clin Microbiol Infect doi: 10.1016/j.cmi.2020.07.049 – volume: 395 start-page: 1054 year: 2020 article-title: Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study publication-title: Lancet doi: 10.1016/S0140-6736(20)30566-3 – volume: 505 start-page: 190 year: 2020 article-title: Procalcitonin in patients with severe coronavirus disease 2019 (COVID-19): a meta-analysis publication-title: Clin Chim Acta doi: 10.1016/j.cca.2020.03.004 – start-page: ASN.2020050615 year: 2020 article-title: Aki in hospitalized patients with COVID-19 publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2020050615 – volume: 382 start-page: 2012 year: 2020 article-title: Covid-19 in critically Ill patients in the seattle region - case series publication-title: N Engl J Med doi: 10.1056/NEJMoa2004500 – volume: 382 start-page: 1476 year: 2020 article-title: SARS-CoV-2 infection among travelers returning from Wuhan, China publication-title: N Engl J Med doi: 10.1056/NEJMc2003100 – volume: 382 start-page: 2372 year: 2020 article-title: Clinical characteristics of Covid-19 in New York City publication-title: N Engl J Med doi: 10.1056/NEJMc2010419 – volume: 20 start-page: 669 year: 2020 article-title: Estimates of the severity of coronavirus disease 2019: a model-based analysis publication-title: Lancet Infect Dis doi: 10.1016/S1473-3099(20)30243-7 – year: 2020 article-title: Epidemiology Working Group for NCIP Epidemic Response, Chinese Center for Disease Control and Prevention. [The epidemiological characteristics of an outbreak of 2019 novel coronavirus diseases (COVID-19) in China] publication-title: China CDC Weekly doi: 10.3760/cma.j.issn.0254-6450.2020.02.003 – volume: 76 start-page: 122 year: 2020 article-title: Association of treatment dose anticoagulation with in-hospital survival among hospitalized patients with COVID-19 publication-title: J Am Coll Cardiol doi: 10.1016/j.jacc.2020.05.001 – volume: 382 year: 2020 article-title: Coagulopathy and antiphospholipid antibodies in patients with Covid-19 publication-title: N Engl J Med doi: 10.1056/NEJMc2007575 – volume: 382 start-page: 2372 year: 2020 ident: 2020112712401907000_10.11.e040736.28 article-title: Clinical characteristics of Covid-19 in New York City publication-title: N Engl J Med doi: 10.1056/NEJMc2010419 – ident: 2020112712401907000_10.11.e040736.22 doi: 10.1016/S0140-6736(20)30566-3 – ident: 2020112712401907000_10.11.e040736.27 doi: 10.1016/j.cca.2020.03.004 – ident: 2020112712401907000_10.11.e040736.1 – ident: 2020112712401907000_10.11.e040736.20 doi: 10.1056/NEJMoa2001191 – volume: 324 start-page: 799 year: 2020 ident: 2020112712401907000_10.11.e040736.11 article-title: Thrombosis in hospitalized patients with COVID-19 in a new York City health system publication-title: JAMA doi: 10.1001/jama.2020.13372 – volume: 395 start-page: 1 year: 2020 ident: 2020112712401907000_10.11.e040736.10 article-title: Difference of coagulation features between severe pneumonia induced by SARS-CoV2 and non-SARS-CoV2 publication-title: J Thromb Thrombolysis – ident: 2020112712401907000_10.11.e040736.21 doi: 10.1016/S1473-3099(20)30243-7 – ident: 2020112712401907000_10.11.e040736.18 doi: 10.1056/NEJMoa2005412 – start-page: ASN.2020050615 year: 2020 ident: 2020112712401907000_10.11.e040736.5 article-title: Aki in hospitalized patients with COVID-19 publication-title: J Am Soc Nephrol doi: 10.1681/ASN.2020050615 – volume: 382 start-page: 1194 year: 2020 ident: 2020112712401907000_10.11.e040736.16 article-title: Defining the Epidemiology of Covid-19 - Studies Needed publication-title: N Engl J Med doi: 10.1056/NEJMp2002125 – ident: 2020112712401907000_10.11.e040736.23 doi: 10.1056/NEJMoa2004500 – volume: 382 start-page: 1476 year: 2020 ident: 2020112712401907000_10.11.e040736.19 article-title: SARS-CoV-2 infection among travelers returning from Wuhan, China publication-title: N Engl J Med doi: 10.1056/NEJMc2003100 – ident: 2020112712401907000_10.11.e040736.2 doi: 10.1056/NEJMoa2002032 – volume: 77 start-page: 198 year: 2020 ident: 2020112712401907000_10.11.e040736.8 article-title: Postmortem examination of COVID‐19 patients reveals diffuse alveolar damage with severe capillary congestion and variegated findings in lungs and other organs suggesting vascular dysfunction publication-title: Histopathology doi: 10.1111/his.14134 – ident: 2020112712401907000_10.11.e040736.25 doi: 10.1001/jama.2020.4326 – ident: 2020112712401907000_10.11.e040736.6 doi: 10.1016/j.jacc.2020.06.007 – ident: 2020112712401907000_10.11.e040736.24 doi: 10.3760/cma.j.issn.0254-6450.2020.02.003 – volume: 323 start-page: 1574 year: 2020 ident: 2020112712401907000_10.11.e040736.12 article-title: Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy publication-title: JAMA doi: 10.1001/jama.2020.5394 – ident: 2020112712401907000_10.11.e040736.9 doi: 10.1056/NEJMc2007575 – ident: 2020112712401907000_10.11.e040736.26 doi: 10.1101/2020.03.24.20040162 – ident: 2020112712401907000_10.11.e040736.4 doi: 10.1681/ASN.2020040509 – ident: 2020112712401907000_10.11.e040736.29 doi: 10.7326/M20-0504 – ident: 2020112712401907000_10.11.e040736.3 doi: 10.1038/s41591-020-0968-3 – ident: 2020112712401907000_10.11.e040736.15 – year: 2020 ident: 2020112712401907000_10.11.e040736.14 article-title: Clinical characteristics, management and in-hospital mortality of patients with coronavirus disease 2019 in Genoa, Italy publication-title: Clin Microbiol Infect doi: 10.1016/j.cmi.2020.07.049 – volume: 8 start-page: 475 year: 2020 ident: 2020112712401907000_10.11.e040736.13 article-title: Clinical course and outcomes of critically ill patients with SARS-CoV-2 pneumonia in Wuhan, China: a single-centered, retrospective, observational study publication-title: Lancet Respir Med doi: 10.1016/S2213-2600(20)30079-5 – ident: 2020112712401907000_10.11.e040736.17 – ident: 2020112712401907000_10.11.e040736.7 doi: 10.1016/j.jacc.2020.05.001 |
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Snippet | ObjectiveThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the... The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the clinical course... ObjectiveThe COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the... Objective The COVID-19 pandemic is a global public health crisis, with over 33 million cases and 999 000 deaths worldwide. Data are needed regarding the... |
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SubjectTerms | Adolescent Adult African Americans Age Aged Aged, 80 and over Blood pressure C-Reactive Protein - metabolism Cardiovascular disease Cohort analysis Comorbidity Coronary vessels Coronaviruses COVID-19 COVID-19 - blood COVID-19 - epidemiology COVID-19 - mortality Critical Care - statistics & numerical data Demographics Diabetes Electronic health records Ethnicity Female Fibrin Fibrinogen Degradation Products - metabolism Heart failure Hispanic Americans Hospital Mortality Hospitalization Hospitals Humans Hypertension Infectious Diseases internal medicine Kidney diseases Laboratories Lymphocytes - metabolism Male Middle Aged Mortality New York City - epidemiology Pacific Islander people Pandemics Patient admissions Pre-existing conditions Procalcitonin - blood Public health Race Retrospective Studies Risk Factors SARS-CoV-2 Vital signs Young Adult |
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Title | Retrospective cohort study of clinical characteristics of 2199 hospitalised patients with COVID-19 in New York City |
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