Expression of innate immune complement regulators on brain epithelial cells during human bacterial meningitis

• Published in: Journal of neuroinflammation Vol. 3; no. 1; p. 22
• Main Authors: Canova, Cecile, Neal, Jim W, Gasque, Philippe
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 02.09.2006; BioMed Central; BMC

In meningitis, the cerebrospinal fluid contains high levels of innate immune molecules (e.g. complement) which are essential to ward off the infectious challenge and to promote the infiltration of phagocytes (neutrophils, monocytes). However, epithelial cells of either the ependymal layer, one of th...