Study protocol of the global Effisayil 1 Phase II, multicentre, randomised, double-blind, placebo-controlled trial of spesolimab in patients with generalized pustular psoriasis presenting with an acute flare - Choon, Siew Eng; Lebwohl, Mark G; Marrakchi, Slaheddine; Burden, A David; Tsai, Tsen-Fang; Morita, Akimichi; Navarini, Alexander A; Zheng, Min; Xu, Jinhua; Turki, Hamida; Rajeswari, Sushmita; Deng, Hongjie; et al. (BMJ open, 2021)
Keywords: clinical trials; Cytokines; Dermatology; dermatopathology; Disease; Double-blind studies; Erythema; Inflammation; Monoclonal antibodies; Mutation; Psoriasis; TNF inhibitors; Tumor necrosis factor-TNF; Thailand; Japan; Taiwan; dermatopathology; psoriasis; clinical trials