Risk of bias and reporting completeness of randomised controlled trials in burn care: protocol for a systematic review

IntroductionBurn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is i...

Full description

Saved in:
Bibliographic Details
Published inBMJ open Vol. 9; no. 12; p. e033472
Main Authors Young, Amber, Reeves, Barnaby C, Cheng, Hung-Yuan, Wasiak, Jason, Muir, Duncan, Davies, Anna, Blazeby, Jane
Format Journal Article
LanguageEnglish
Published England British Medical Journal Publishing Group 18.12.2019
BMJ Publishing Group LTD
BMJ Publishing Group
Subjects
Bias
Burns
Burns - therapy
Citation management software
cochrane
Collaboration
consort
Human subjects
Humans
Injuries
Intervention
Laboratories
quality
randomised controlled trials as topic
Randomized Controlled Trials as Topic - standards
Research Methods
Systematic review
Systematic Reviews as Topic
Validity
cochrane
randomised controlled trials as topic
consort
bias
burns
quality
Online AccessGet full text
ISSN2044-6055
2044-6055
DOI10.1136/bmjopen-2019-033472

Cover

Abstract IntroductionBurn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration.Methods and analysisA systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including ‘burn’, ‘scald’, ‘thermal injury’ and ‘RCT’. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss’s Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains.Ethics and disseminationNo ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences.PROSPERO registration numberCRD42018111020.
AbstractList Burn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration. A systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including 'burn', 'scald', 'thermal injury' and 'RCT'. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss's Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains. No ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences. CRD42018111020.
Introduction Burn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration.Methods and analysis A systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including ‘burn’, ‘scald’, ‘thermal injury’ and ‘RCT’. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss’s Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains.Ethics and dissemination No ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences.PROSPERO registration number CRD42018111020.
IntroductionBurn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration.Methods and analysisA systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including ‘burn’, ‘scald’, ‘thermal injury’ and ‘RCT’. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss’s Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains.Ethics and disseminationNo ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences.PROSPERO registration numberCRD42018111020.
Burn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration.INTRODUCTIONBurn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires evidence which is best obtained through high-quality randomised controlled trials (RCT). The number of published RCTs of burn care is increasing. However, trial quality and reporting standards are unclear. This study will assess the risk of bias and adequacy of reporting in recent burn care RCTs using tools endorsed by the Cochrane Collaboration.A systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including 'burn', 'scald', 'thermal injury' and 'RCT'. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss's Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains.METHODS AND ANALYSISA systematic literature review will be undertaken, assessing parallel group RCTs evaluating therapeutic interventions for patients with cutaneous burns. Literature searches will use Ovid Medline, Ovid Embase, Web of Science and the Cochrane Library. Separate searches for each database will include medical subject heading and free text terms including 'burn', 'scald', 'thermal injury' and 'RCT'. Two reviewers will independently assess each study for inclusion. Risk of bias (RoB) will be assessed with the revised tool (RoB 2) and reporting completeness with the CONsolidated Standards of Reporting Trials (CONSORT) 2010 guidelines. We will report a narrative synthesis of all studies, including domain specific, and overall risk of bias for the primary outcome of each trial. Inter-rater agreement for RoB 2 will be reported using Fleiss's Kappa. For adherence to the CONSORT guidelines, we will generate a completeness of reporting index for the five domains.No ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences.ETHICS AND DISSEMINATIONNo ethics approval is required because published documents will be used. Findings of the study will be disseminated in a peer-reviewed journal and presented at conferences.CRD42018111020.PROSPERO REGISTRATION NUMBERCRD42018111020.
Author Wasiak, Jason
Cheng, Hung-Yuan
Young, Amber
Blazeby, Jane
Davies, Anna
Reeves, Barnaby C
Muir, Duncan
AuthorAffiliation 6 Austin Health Clinical School of Nursing , Latrobe University , Heidelberg , Victoria , Australia
3 Bristol Trials Centre (BRI-Hub) , Bristol Medical School, University of Bristol , Bristol , UK
1 Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School , University of Bristol , Bristol , UK
5 Olivia Newton John Cancer Wellness & Research Centre, Department of Radiation Oncology , Austin Health , Heidelberg , Victoria , Australia
4 Population Health Sciences , Bristol Medical School, University of Bristol , Bristol , UK
2 Paediatric Anaesthesia , University Hospitals Bristol NHS Foundation Trust , Bristol , UK
7 Centre for Academic Child Health , University of Bristol , Bristol , UK
8 NIHR Biomedical Research Centre , University of Bristol and University hospitals Bristol NHS Foundation Trust , Bristol , UK
AuthorAffiliation_xml – name: 8 NIHR Biomedical Research Centre , University of Bristol and University hospitals Bristol NHS Foundation Trust , Bristol , UK
– name: 4 Population Health Sciences , Bristol Medical School, University of Bristol , Bristol , UK
– name: 5 Olivia Newton John Cancer Wellness & Research Centre, Department of Radiation Oncology , Austin Health , Heidelberg , Victoria , Australia
– name: 6 Austin Health Clinical School of Nursing , Latrobe University , Heidelberg , Victoria , Australia
– name: 3 Bristol Trials Centre (BRI-Hub) , Bristol Medical School, University of Bristol , Bristol , UK
– name: 1 Bristol Centre for Surgical Research, Population Health Sciences, Bristol Medical School , University of Bristol , Bristol , UK
– name: 2 Paediatric Anaesthesia , University Hospitals Bristol NHS Foundation Trust , Bristol , UK
– name: 7 Centre for Academic Child Health , University of Bristol , Bristol , UK
Author_xml – sequence: 1
  givenname: Amber
  orcidid: 0000-0001-7205-492X
  surname: Young
  fullname: Young, Amber
  email: amber.young1@nhs.net
  organization: Paediatric Anaesthesia, University Hospitals Bristol NHS Foundation Trust, Bristol, UK
– sequence: 2
  givenname: Barnaby C
  orcidid: 0000-0002-5101-9487
  surname: Reeves
  fullname: Reeves, Barnaby C
  organization: Bristol Trials Centre (BRI-Hub), Bristol Medical School, University of Bristol, Bristol, UK
– sequence: 3
  givenname: Hung-Yuan
  surname: Cheng
  fullname: Cheng, Hung-Yuan
  organization: Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
– sequence: 4
  givenname: Jason
  surname: Wasiak
  fullname: Wasiak, Jason
  organization: Austin Health Clinical School of Nursing, Latrobe University, Heidelberg, Victoria, Australia
– sequence: 5
  givenname: Duncan
  surname: Muir
  fullname: Muir, Duncan
  organization: Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK
– sequence: 6
  givenname: Anna
  surname: Davies
  fullname: Davies, Anna
  organization: Centre for Academic Child Health, University of Bristol, Bristol, UK
– sequence: 7
  givenname: Jane
  surname: Blazeby
  fullname: Blazeby, Jane
  organization: NIHR Biomedical Research Centre, University of Bristol and University hospitals Bristol NHS Foundation Trust, Bristol, UK
BackLink https://www.ncbi.nlm.nih.gov/pubmed/31857316$$D View this record in MEDLINE/PubMed
BookMark eNqNUltrFDEUHqRia-0vECTgiy_T5jKZTHwQSvFSKAiizyHJnKxZZ5IxmV3pvzfjrmvbBzUEcsj5vu9cn1ZHIQaoqucEnxPC2gszruMEoaaYyBoz1gj6qDqhuGnqFnN-dMc-rs5yXuNyGi45p0-qY0Y6LhhpT6rtJ5-_oeiQ8TojHXqUYIpp9mGFbBynAWYIkPMCScUdR5-hL64wpzgMxZyT10NGPiCzSQFZneA1mlKco40DcjEhjfJtnmHUs7dFfuvhx7PqsSssONu_p9WXd28_X32obz6-v766vKkNF91cc4sbMLrvsCPaUiehZA19zygnDGtW3s5o7GjDHO2wsI5pgiUmVojOGstOq-udbh_1Wk3Jjzrdqqi9-vUR00rpUqwdQAkCWPSydw1frtTUGXCtNabtGOZd0Xqz05o2ZoTeQmmBHu6J3vcE_1Wt4la1kglCZBF4tRdI8fsG8qxKMy0Mgw4QN1lRRqUooXhToC8fQNexdLe0qqAawQWXdBF8cTejQyq_x1sAbAewKeacwB0gBKtlj9R-j9SyR2q3R4UlH7Csn8vwlplrP_yDe77jFud_Brv4QzgU-TfGT_Yt71s
CitedBy_id crossref_primary_10_1093_burnst_tkaa039
crossref_primary_10_1136_bmjopen_2021_052528
Cites_doi 10.2522/ptj.20070147
10.1136/bmj.d5928
10.1136/bmjopen-2017-019703
10.1111/medu.13130
10.1186/1745-6215-10-27
10.1016/j.jclinepi.2012.07.005
10.1186/2046-4053-4-1
10.1136/bmj.l4898
10.1111/wrr.12119
10.1002/14651858.CD011821.pub2
10.1016/j.burns.2010.03.011
10.1016/S0140-6736(16)31592-6
10.1136/bmjopen-2018-025135
10.1016/j.burns.2017.11.001
10.1111/jebm.12141
10.1136/bmj.g7647
10.1371/journal.pmed.1001987
10.1111/j.1875-595X.2011.00007.x
10.1136/bmjopen-2017-017267
10.1186/s13643-018-0746-1
10.1097/BRS.0b013e31822671eb
10.1016/j.burns.2012.04.007
10.1186/1741-7015-8-18
10.1016/S0895-4356(00)00360-7
10.1016/0197-2456(94)00031-W
10.1136/bmj.b4012
10.1371/journal.pone.0096920
10.1177/0962280216643347
10.1097/BCR.0b013e31829b0075
10.20982/tqmp.08.1.p023
10.1136/bmj.h809
10.1016/S0140-6736(04)17670-8
10.1016/S0140-6736(13)62227-8
10.1016/S0140-6736(13)61093-4
10.1016/S0140-6736(09)60329-9
10.1016/j.burns.2009.04.031
10.1136/bmj.316.7146.1719
ContentType Journal Article
Copyright Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.
2019 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. 2019
Copyright_xml – notice: Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.
– notice: 2019 Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/ . Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.
– notice: Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. 2019
DBID 9YT
ACMMV
AAYXX
CITATION
CGR
CUY
CVF
ECM
EIF
NPM
3V.
7RV
7X7
7XB
88E
88G
8FI
8FJ
8FK
ABUWG
AFKRA
AZQEC
BENPR
BTHHO
CCPQU
DWQXO
FYUFA
GHDGH
GNUQQ
K9-
K9.
KB0
M0R
M0S
M1P
M2M
NAPCQ
PHGZM
PHGZT
PIMPY
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PSYQQ
Q9U
7X8
5PM
DOA
DOI 10.1136/bmjopen-2019-033472
DatabaseName BMJ Open Access Journals
BMJ Journals:Open Access
CrossRef
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Central (Corporate)
Nursing & Allied Health Database
Health & Medical Collection (ProQuest)
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Psychology Database (Alumni)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central Essentials
ProQuest Central
BMJ Journals
ProQuest One Community College
ProQuest Central Korea
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
Consumer Health Database (Alumni Edition)
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Consumer Health Database (ProQuest)
ProQuest Health & Medical Collection
Medical Database
Psychology Database (ProQuest)
Nursing & Allied Health Premium
Proquest Central Premium
ProQuest One Academic (New)
Publicly Available Content Database
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest One Psychology
ProQuest Central Basic
MEDLINE - Academic
PubMed Central (Full Participant titles)
DOAJ Directory of Open Access Journals
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
Publicly Available Content Database
ProQuest One Psychology
ProQuest Central Student
ProQuest One Academic Middle East (New)
ProQuest Central Essentials
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Family Health (Alumni Edition)
ProQuest Central China
ProQuest Central
ProQuest Health & Medical Research Collection
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest Central Basic
ProQuest Family Health
ProQuest One Academic Eastern Edition
ProQuest Nursing & Allied Health Source
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Psychology Journals (Alumni)
ProQuest Hospital Collection (Alumni)
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest Psychology Journals
ProQuest One Academic UKI Edition
BMJ Journals
ProQuest Nursing & Allied Health Source (Alumni)
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE


MEDLINE - Academic
Publicly Available Content Database
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 3
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 4
  dbid: ACMMV
  name: BMJ Journals:Open Access
  url: https://journals.bmj.com/
  sourceTypes: Publisher
– sequence: 5
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
EISSN 2044-6055
ExternalDocumentID oai_doaj_org_article_71e07d9df45f45f9a2fbef6cbb683058
PMC6937119
31857316
10_1136_bmjopen_2019_033472
bmjopen
Genre Research Support, Non-U.S. Gov't
Journal Article
GrantInformation_xml – fundername: Research Trainees Coordinating Centre
  grantid: DRF-2016-09-031
  funderid: http://dx.doi.org/10.13039/501100000659
– fundername: Department of Health
  grantid: DRF-2016-09-031
– fundername: ;
  grantid: DRF-2016-09-031
GroupedDBID ---
4.4
53G
5VS
7RV
7X7
7~R
88E
8FI
8FJ
9YT
ABUWG
ACGFS
ACMMV
ADBBV
AENEX
AFKRA
ALIPV
ALMA_UNASSIGNED_HOLDINGS
AOIJS
AZQEC
BAWUL
BCNDV
BENPR
BKNYI
BPHCQ
BTFSW
BTHHO
CCPQU
DIK
DWQXO
EBS
FYUFA
GNUQQ
GROUPED_DOAJ
GX1
H13
HMCUK
HYE
HZ~
K9-
KQ8
M0R
M1P
M2M
M48
M~E
NAPCQ
O9-
OK1
PGMZT
PHGZT
PIMPY
PQQKQ
PROAC
PSQYO
PSYQQ
RHI
RMJ
RPM
UKHRP
AAYXX
ADRAZ
BVXVI
CITATION
EJD
PHGZM
CGR
CUY
CVF
ECM
EIF
NPM
PJZUB
PPXIY
3V.
7XB
8FK
K9.
PKEHL
PQEST
PQUKI
PRINS
Q9U
7X8
PUEGO
5PM
ID FETCH-LOGICAL-b578t-5c04ebad80f1ac2f9e731edd325130a33258ba0f243f2807cf3a10901c778cbc3
IEDL.DBID 9YT
ISSN 2044-6055
IngestDate Wed Aug 27 01:16:15 EDT 2025
Thu Aug 21 13:54:26 EDT 2025
Fri Sep 05 06:57:28 EDT 2025
Fri Jul 25 22:50:24 EDT 2025
Mon Jul 21 06:05:04 EDT 2025
Tue Jul 01 03:00:03 EDT 2025
Thu Apr 24 22:50:27 EDT 2025
Thu Apr 24 22:49:01 EDT 2025
Thu Apr 24 22:50:20 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 12
Keywords cochrane
randomised controlled trials as topic
consort
bias
burns
quality
Language English
License This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ.
This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-b578t-5c04ebad80f1ac2f9e731edd325130a33258ba0f243f2807cf3a10901c778cbc3
Notes Protocol
ObjectType-Article-2
SourceType-Scholarly Journals-1
content type line 14
ObjectType-Feature-3
ObjectType-Evidence Based Healthcare-1
ObjectType-Article-1
ObjectType-Feature-2
content type line 23
ORCID 0000-0002-5101-9487
0000-0001-7205-492X
OpenAccessLink http://dx.doi.org/10.1136/bmjopen-2019-033472
PMID 31857316
PQID 2347575929
PQPubID 2040975
ParticipantIDs doaj_primary_oai_doaj_org_article_71e07d9df45f45f9a2fbef6cbb683058
pubmedcentral_primary_oai_pubmedcentral_nih_gov_6937119
proquest_miscellaneous_2329730554
proquest_journals_2347575929
pubmed_primary_31857316
crossref_primary_10_1136_bmjopen_2019_033472
crossref_citationtrail_10_1136_bmjopen_2019_033472
bmj_primary_10_1136_bmjopen_2019_033472
bmj_journals_10_1136_bmjopen_2019_033472
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2019-12-18
PublicationDateYYYYMMDD 2019-12-18
PublicationDate_xml – month: 12
  year: 2019
  text: 2019-12-18
  day: 18
PublicationDecade 2010
PublicationPlace England
PublicationPlace_xml – name: England
– name: London
– name: BMA House, Tavistock Square, London, WC1H 9JR
PublicationTitle BMJ open
PublicationTitleAbbrev BMJ Open
PublicationTitleAlternate BMJ Open
PublicationYear 2019
Publisher British Medical Journal Publishing Group
BMJ Publishing Group LTD
BMJ Publishing Group
Publisher_xml – name: British Medical Journal Publishing Group
– name: BMJ Publishing Group LTD
– name: BMJ Publishing Group
References Shahrokhi, Arno, Jeschke (R8) 2014; 22
Norman, Christie, Liu (R10) 2017; 10
Zeng, Zhang, Kwong (R24) 2015; 8
Glanville, Lefebvre, Miles (R34) 2006; 94
Schulz, Altman, Moher (R46) 2010; 8
Armijo-Olivo, Ospina, da Costa (R39) 2014; 9
Verhagen, de Vet, de Bie (R25) 2001; 54
Graham, Haines, Goldsmith (R40) 2012; 37
Moher, Jadad, Nichol (R22) 1995; 16
Hartling, Hamm, Milne (R41) 2013; 66
Moher, Hopewell, Schulz (R28) 2010; 340
Danilla, Wasiak, Searle (R14) 2009; 35
Cioffi, Farella (R20) 2011; 61
Page, McKenzie, Higgins (R26) 2018; 8
Shamseer, Moher, Clarke (R30) 2015; 349
Yordanov, Dechartres, Porcher (R2) 2015; 350
Jeschke, Herndon (R7) 2014; 383
Jeschke, Finnerty, Shahrokhi (R5) 2013; 34
Ioannidis, Greenland, Hlatky (R3) 2014; 383
Sinha, Yoon, Shin (R16) 2018; 44
Olivo, Macedo, Gadotti (R23) 2008; 88
Al-Benna, Alzoubaidi, Al-Ajam (R15) 2010; 36
Mills, Chan, Wu (R32) 2009; 10
Moher, Shamseer, Clarke (R29) 2015; 4
Rothwell (R17) 2005; 365
Hallgren (R44) 2012; 8
Hartling, Ospina, Liang (R42) 2009; 339
Sibbald, Roberts (R33) 1998; 316
Horsley, Galipeau, Petkovic (R47) 2017; 51
Young, Davies, Bland (R9) 2019; 9
Bilandzic, Fitzpatrick, Rosella (R43) 2016; 13
Selig, Lumenta, Giretzlehner (R6) 2012; 38
Higgins, Altman, Gøtzsche (R18) 2011; 343
Chalmers, Glasziou (R1) 2009; 374
Djulbegovic, Guyatt (R21) 2017; 390
Jüni, Altman, Egger (R4) 2001; 323
Sterne, Savović, Page (R27) 2019; 366
Breederveld, Tuinebreijer (R11) 2012; 12
Gates, Gates, Duarte (R37) 2018; 7
(R35) 2019
Nelson, Edwards (R45) 2018; 27
Young, Brookes, Rumsey (R36) 2017; 7
Chalmers, Glasziou 2009; 374
Higgins, Altman, Gøtzsche 2011; 343
Al-Benna, Alzoubaidi, Al-Ajam 2010; 36
Verhagen, de Vet, de Bie 2001; 54
Glanville, Lefebvre, Miles 2006; 94
Gates, Gates, Duarte 2018; 7
Hartling, Ospina, Liang 2009; 339
Jüni, Altman, Egger 2001; 323
Danilla, Wasiak, Searle 2009; 35
Young, Brookes, Rumsey 2017; 7
Sinha, Yoon, Shin 2018; 44
Graham, Haines, Goldsmith 2012; 37
Ioannidis, Greenland, Hlatky 2014; 383
Young, Davies, Bland 2019; 9
Breederveld, Tuinebreijer 2012; 12
Selig, Lumenta, Giretzlehner 2012; 38
Olivo, Macedo, Gadotti 2008; 88
Moher, Hopewell, Schulz 2010; 340
Sibbald, Roberts 1998; 316
Sterne, Savović, Page 2019; 366
Bilandzic, Fitzpatrick, Rosella 2016; 13
Zeng, Zhang, Kwong 2015; 8
Moher, Shamseer, Clarke 2015; 4
Hallgren 2012; 8
Mills, Chan, Wu 2009; 10
Djulbegovic, Guyatt 2017; 390
Rothwell 2005; 365
Cioffi, Farella 2011; 61
Norman, Christie, Liu 2017; 10
Horsley, Galipeau, Petkovic 2017; 51
2019
Hartling, Hamm, Milne 2013; 66
Jeschke, Herndon 2014; 383
Moher, Jadad, Nichol 1995; 16
Yordanov, Dechartres, Porcher 2015; 350
Schulz, Altman, Moher 2010; 8
Armijo-Olivo, Ospina, da Costa 2014; 9
Shahrokhi, Arno, Jeschke 2014; 22
Nelson, Edwards 2018; 27
Page, McKenzie, Higgins 2018; 8
Shamseer, Moher, Clarke 2015; 349
Jeschke, Finnerty, Shahrokhi 2013; 34
References_xml – volume: 88
  start-page: 156
  year: 2008
  ident: R23
  article-title: Scales to assess the quality of randomized controlled trials: a systematic review
  publication-title: Phys Ther
  doi: 10.2522/ptj.20070147
– volume: 343
  year: 2011
  ident: R18
  article-title: The Cochrane collaboration's tool for assessing risk of bias in randomised trials
  publication-title: BMJ
  doi: 10.1136/bmj.d5928
– volume: 94
  year: 2006
  ident: R34
  article-title: How to identify randomized controlled trials in MEDLINE: ten years on
  publication-title: J Med Libr Assoc
– volume: 8
  year: 2018
  ident: R26
  article-title: Tools for assessing risk of reporting biases in studies and syntheses of studies: a systematic review
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2017-019703
– volume: 51
  start-page: 61
  year: 2017
  ident: R47
  article-title: Reporting quality and risk of bias in randomised trials in health professions education
  publication-title: Med Educ
  doi: 10.1111/medu.13130
– volume: 10
  year: 2009
  ident: R32
  article-title: Design, analysis, and presentation of crossover trials
  publication-title: Trials
  doi: 10.1186/1745-6215-10-27
– volume: 66
  start-page: 973
  year: 2013
  ident: R41
  article-title: Testing the risk of bias tool showed low reliability between individual reviewers and across consensus assessments of reviewer pairs
  publication-title: J Clin Epidemiol
  doi: 10.1016/j.jclinepi.2012.07.005
– volume: 4
  year: 2015
  ident: R29
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement
  publication-title: Syst Rev
  doi: 10.1186/2046-4053-4-1
– volume: 366
  year: 2019
  ident: R27
  article-title: Rob 2: a revised tool for assessing risk of bias in randomised trials
  publication-title: BMJ
  doi: 10.1136/bmj.l4898
– volume: 22
  start-page: 14
  year: 2014
  ident: R8
  article-title: The use of dermal substitutes in burn surgery: acute phase
  publication-title: Wound Repair Regen
  doi: 10.1111/wrr.12119
– volume: 10
  year: 2017
  ident: R10
  article-title: Antiseptics for burns
  publication-title: Cochrane Database Syst Rev
  doi: 10.1002/14651858.CD011821.pub2
– volume: 36
  start-page: 1190
  year: 2010
  ident: R15
  article-title: Evidence-Based burn care—An assessment of the methodological quality of research published in burn care journals from 1982 to 2008
  publication-title: Burns
  doi: 10.1016/j.burns.2010.03.011
– volume: 390
  start-page: 415
  year: 2017
  ident: R21
  article-title: Progress in evidence-based medicine: a quarter century on
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(16)31592-6
– volume: 9
  year: 2019
  ident: R9
  article-title: Systematic review of clinical outcome reporting in randomised controlled trials of burn care
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2018-025135
– volume: 44
  start-page: 263
  year: 2018
  ident: R16
  article-title: Burn clinical trials: a systematic review of registration and publications
  publication-title: Burns
  doi: 10.1016/j.burns.2017.11.001
– volume: 8
  start-page: 2
  year: 2015
  ident: R24
  article-title: The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review
  publication-title: J Evid Based Med
  doi: 10.1111/jebm.12141
– volume: 349
  year: 2015
  ident: R30
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation
  publication-title: BMJ
  doi: 10.1136/bmj.g7647
– volume: 323
  start-page: 42
  year: 2001
  ident: R4
  article-title: Assessing the quality of controlled clinical trials
  publication-title: Bmj
– volume: 13
  year: 2016
  ident: R43
  article-title: Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors: application of a new Cochrane risk of bias tool
  publication-title: PLoS Med
  doi: 10.1371/journal.pmed.1001987
– volume: 61
  start-page: 37
  year: 2011
  ident: R20
  article-title: Quality of randomised controlled trials in dentistry
  publication-title: Int Dent J
  doi: 10.1111/j.1875-595X.2011.00007.x
– volume: 7
  year: 2017
  ident: R36
  article-title: Agreement on what to measure in randomised controlled trials in burn care: study protocol for the development of a core outcome set
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2017-017267
– volume: 7
  year: 2018
  ident: R37
  article-title: Evaluation of the reliability, usability, and applicability of AMSTAR, AMSTAR 2, and ROBIS: protocol for a descriptive analytic study
  publication-title: Syst Rev
  doi: 10.1186/s13643-018-0746-1
– volume: 37
  start-page: 515
  year: 2012
  ident: R40
  article-title: Reliability of 3 assessment tools used to evaluate randomized controlled trials for treatment of neck pain
  publication-title: Spine
  doi: 10.1097/BRS.0b013e31822671eb
– volume: 38
  start-page: 960
  year: 2012
  ident: R6
  article-title: The properties of an “ideal” burn wound dressing – What do we need in daily clinical practice? Results of a worldwide online survey among burn care specialists
  publication-title: Burns
  doi: 10.1016/j.burns.2012.04.007
– volume: 8
  year: 2010
  ident: R46
  article-title: Consort 2010 statement: updated guidelines for reporting parallel group randomised trials
  publication-title: BMC Med
  doi: 10.1186/1741-7015-8-18
– volume: 54
  start-page: 651
  year: 2001
  ident: R25
  article-title: The art of quality assessment of RCTs included in systematic reviews
  publication-title: J Clin Epidemiol
  doi: 10.1016/S0895-4356(00)00360-7
– volume: 16
  start-page: 62
  year: 1995
  ident: R22
  article-title: Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists
  publication-title: Control Clin Trials
  doi: 10.1016/0197-2456(94)00031-W
– volume: 339
  year: 2009
  ident: R42
  article-title: Risk of bias versus quality assessment of randomised controlled trials: cross sectional study
  publication-title: BMJ
  doi: 10.1136/bmj.b4012
– year: 2019
  ident: R35
  article-title: Study design search filters
  publication-title: BMJ Best Practice
– volume: 9
  year: 2014
  ident: R39
  article-title: Poor reliability between Cochrane reviewers and blinded external reviewers when applying the Cochrane risk of bias tool in physical therapy trials
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0096920
– volume: 27
  start-page: 812
  year: 2018
  ident: R45
  article-title: A measure of association for ordered categorical data in population-based studies
  publication-title: Stat Methods Med Res
  doi: 10.1177/0962280216643347
– volume: 34
  start-page: 612
  year: 2013
  ident: R5
  article-title: Wound coverage technologies in burn care: novel techniques
  publication-title: J Burn Care Res
  doi: 10.1097/BCR.0b013e31829b0075
– volume: 8
  start-page: 23
  year: 2012
  ident: R44
  article-title: Computing inter-rater reliability for observational data: an overview and tutorial
  publication-title: Tutor Quant Methods Psychol
  doi: 10.20982/tqmp.08.1.p023
– volume: 350
  year: 2015
  ident: R2
  article-title: Avoidable waste of research related to inadequate methods in clinical trials
  publication-title: BMJ
  doi: 10.1136/bmj.h809
– volume: 365
  start-page: 82
  year: 2005
  ident: R17
  article-title: External validity of randomised controlled trials: “To whom do the results of this trial apply?”
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(04)17670-8
– volume: 340
  year: 2010
  ident: R28
  article-title: Consort 2010 statement: updated guidelines for reporting parallel group randomised trials
  publication-title: BMJ (Clinical research
– volume: 12
  year: 2012
  ident: R11
  article-title: Recombinant human growth hormone for treating burns and donor sites
  publication-title: Cochrane Database Syst Rev
– volume: 383
  start-page: 166
  year: 2014
  ident: R3
  article-title: Increasing value and reducing waste in research design, conduct, and analysis
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(13)62227-8
– volume: 383
  start-page: 1168
  year: 2014
  ident: R7
  article-title: Burns in children: standard and new treatments
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(13)61093-4
– volume: 374
  start-page: 86
  year: 2009
  ident: R1
  article-title: Avoidable waste in the production and reporting of research evidence
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(09)60329-9
– volume: 35
  start-page: 956
  year: 2009
  ident: R14
  article-title: Methodological quality of randomised controlled trials in burns care. A systematic review
  publication-title: Burns
  doi: 10.1016/j.burns.2009.04.031
– volume: 316
  start-page: 1719
  year: 1998
  ident: R33
  article-title: Understanding controlled trials: crossover trials
  publication-title: BMJ
  doi: 10.1136/bmj.316.7146.1719
– volume: 38
  start-page: 960
  year: 2012
  article-title: The properties of an “ideal” burn wound dressing – What do we need in daily clinical practice? Results of a worldwide online survey among burn care specialists
  publication-title: Burns
  doi: 10.1016/j.burns.2012.04.007
– volume: 365
  start-page: 82
  year: 2005
  article-title: External validity of randomised controlled trials: “To whom do the results of this trial apply?”
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(04)17670-8
– volume: 7
  year: 2018
  article-title: Evaluation of the reliability, usability, and applicability of AMSTAR, AMSTAR 2, and ROBIS: protocol for a descriptive analytic study
  publication-title: Syst Rev
  doi: 10.1186/s13643-018-0746-1
– volume: 94
  year: 2006
  article-title: How to identify randomized controlled trials in MEDLINE: ten years on
  publication-title: J Med Libr Assoc
– volume: 88
  start-page: 156
  year: 2008
  article-title: Scales to assess the quality of randomized controlled trials: a systematic review
  publication-title: Phys Ther
  doi: 10.2522/ptj.20070147
– volume: 340
  year: 2010
  article-title: Consort 2010 statement: updated guidelines for reporting parallel group randomised trials
  publication-title: BMJ (Clinical research
– volume: 35
  start-page: 956
  year: 2009
  article-title: Methodological quality of randomised controlled trials in burns care. A systematic review
  publication-title: Burns
  doi: 10.1016/j.burns.2009.04.031
– volume: 10
  year: 2009
  article-title: Design, analysis, and presentation of crossover trials
  publication-title: Trials
  doi: 10.1186/1745-6215-10-27
– volume: 374
  start-page: 86
  year: 2009
  article-title: Avoidable waste in the production and reporting of research evidence
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(09)60329-9
– volume: 34
  start-page: 612
  year: 2013
  article-title: Wound coverage technologies in burn care: novel techniques
  publication-title: J Burn Care Res
  doi: 10.1097/BCR.0b013e31829b0075
– year: 2019
  article-title: Study design search filters
  publication-title: BMJ Best Practice
– volume: 8
  year: 2010
  article-title: Consort 2010 statement: updated guidelines for reporting parallel group randomised trials
  publication-title: BMC Med
  doi: 10.1186/1741-7015-8-18
– volume: 37
  start-page: 515
  year: 2012
  article-title: Reliability of 3 assessment tools used to evaluate randomized controlled trials for treatment of neck pain
  publication-title: Spine
  doi: 10.1097/BRS.0b013e31822671eb
– volume: 8
  start-page: 23
  year: 2012
  article-title: Computing inter-rater reliability for observational data: an overview and tutorial
  publication-title: Tutor Quant Methods Psychol
  doi: 10.20982/tqmp.08.1.p023
– volume: 16
  start-page: 62
  year: 1995
  article-title: Assessing the quality of randomized controlled trials: an annotated bibliography of scales and checklists
  publication-title: Control Clin Trials
  doi: 10.1016/0197-2456(94)00031-W
– volume: 44
  start-page: 263
  year: 2018
  article-title: Burn clinical trials: a systematic review of registration and publications
  publication-title: Burns
  doi: 10.1016/j.burns.2017.11.001
– volume: 10
  year: 2017
  article-title: Antiseptics for burns
  publication-title: Cochrane Database Syst Rev
  doi: 10.1002/14651858.CD011821.pub2
– volume: 61
  start-page: 37
  year: 2011
  article-title: Quality of randomised controlled trials in dentistry
  publication-title: Int Dent J
  doi: 10.1111/j.1875-595X.2011.00007.x
– volume: 9
  year: 2019
  article-title: Systematic review of clinical outcome reporting in randomised controlled trials of burn care
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2018-025135
– volume: 27
  start-page: 812
  year: 2018
  article-title: A measure of association for ordered categorical data in population-based studies
  publication-title: Stat Methods Med Res
  doi: 10.1177/0962280216643347
– volume: 51
  start-page: 61
  year: 2017
  article-title: Reporting quality and risk of bias in randomised trials in health professions education
  publication-title: Med Educ
  doi: 10.1111/medu.13130
– volume: 7
  year: 2017
  article-title: Agreement on what to measure in randomised controlled trials in burn care: study protocol for the development of a core outcome set
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2017-017267
– volume: 36
  start-page: 1190
  year: 2010
  article-title: Evidence-Based burn care—An assessment of the methodological quality of research published in burn care journals from 1982 to 2008
  publication-title: Burns
  doi: 10.1016/j.burns.2010.03.011
– volume: 383
  start-page: 1168
  year: 2014
  article-title: Burns in children: standard and new treatments
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(13)61093-4
– volume: 383
  start-page: 166
  year: 2014
  article-title: Increasing value and reducing waste in research design, conduct, and analysis
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(13)62227-8
– volume: 323
  start-page: 42
  year: 2001
  article-title: Assessing the quality of controlled clinical trials
  publication-title: Bmj
– volume: 343
  year: 2011
  article-title: The Cochrane collaboration's tool for assessing risk of bias in randomised trials
  publication-title: BMJ
  doi: 10.1136/bmj.d5928
– volume: 390
  start-page: 415
  year: 2017
  article-title: Progress in evidence-based medicine: a quarter century on
  publication-title: The Lancet
  doi: 10.1016/S0140-6736(16)31592-6
– volume: 22
  start-page: 14
  year: 2014
  article-title: The use of dermal substitutes in burn surgery: acute phase
  publication-title: Wound Repair Regen
  doi: 10.1111/wrr.12119
– volume: 12
  year: 2012
  article-title: Recombinant human growth hormone for treating burns and donor sites
  publication-title: Cochrane Database Syst Rev
– volume: 9
  year: 2014
  article-title: Poor reliability between Cochrane reviewers and blinded external reviewers when applying the Cochrane risk of bias tool in physical therapy trials
  publication-title: PLoS One
  doi: 10.1371/journal.pone.0096920
– volume: 8
  year: 2018
  article-title: Tools for assessing risk of reporting biases in studies and syntheses of studies: a systematic review
  publication-title: BMJ Open
  doi: 10.1136/bmjopen-2017-019703
– volume: 8
  start-page: 2
  year: 2015
  article-title: The methodological quality assessment tools for preclinical and clinical studies, systematic review and meta-analysis, and clinical practice guideline: a systematic review
  publication-title: J Evid Based Med
  doi: 10.1111/jebm.12141
– volume: 366
  year: 2019
  article-title: Rob 2: a revised tool for assessing risk of bias in randomised trials
  publication-title: BMJ
  doi: 10.1136/bmj.l4898
– volume: 316
  start-page: 1719
  year: 1998
  article-title: Understanding controlled trials: crossover trials
  publication-title: BMJ
  doi: 10.1136/bmj.316.7146.1719
– volume: 349
  year: 2015
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation
  publication-title: BMJ
  doi: 10.1136/bmj.g7647
– volume: 4
  year: 2015
  article-title: Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015 statement
  publication-title: Syst Rev
  doi: 10.1186/2046-4053-4-1
– volume: 339
  year: 2009
  article-title: Risk of bias versus quality assessment of randomised controlled trials: cross sectional study
  publication-title: BMJ
  doi: 10.1136/bmj.b4012
– volume: 54
  start-page: 651
  year: 2001
  article-title: The art of quality assessment of RCTs included in systematic reviews
  publication-title: J Clin Epidemiol
  doi: 10.1016/S0895-4356(00)00360-7
– volume: 13
  year: 2016
  article-title: Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors: application of a new Cochrane risk of bias tool
  publication-title: PLoS Med
  doi: 10.1371/journal.pmed.1001987
– volume: 350
  year: 2015
  article-title: Avoidable waste of research related to inadequate methods in clinical trials
  publication-title: BMJ
  doi: 10.1136/bmj.h809
– volume: 66
  start-page: 973
  year: 2013
  article-title: Testing the risk of bias tool showed low reliability between individual reviewers and across consensus assessments of reviewer pairs
  publication-title: J Clin Epidemiol
  doi: 10.1016/j.jclinepi.2012.07.005
SSID ssj0000459552
Score 2.2135508
Snippet IntroductionBurn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies...
Burn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies requires...
Introduction Burn care represents a healthcare and economic burden to patients internationally. Choice of the most clinically effective treatment strategies...
SourceID doaj
pubmedcentral
proquest
pubmed
crossref
bmj
SourceType Open Website
Open Access Repository
Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage e033472
SubjectTerms Bias
Burns
Burns - therapy
Citation management software
cochrane
Collaboration
consort
Human subjects
Humans
Injuries
Intervention
Laboratories
quality
randomised controlled trials as topic
Randomized Controlled Trials as Topic - standards
Research Methods
Systematic review
Systematic Reviews as Topic
Validity
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3Na9VAEB-0B_Ei9TtaZQVBD4Zmv5KsNxVLEfQgFnoL-4nP1kR8r_37ndlsX98TqR6EQEJ2Ntns_HZnws7-BuB58i6a4HjNvTe1QpNaOyd8LVxCd127ztoc5fupPTxSH4718UaqL4oJm-mB547b73hsumBCUpoOY0VyMbXeubZHrOZtvo1pNn6m8hystNFaFJohLtt99_0b5aNCVNCuHSkVcQJfx7tbBinz9v_J2fw9ZnLDCB3swq3iPbI3c6tvw7U43oEbH8v6-F04_7xYnrApMbewS2bHwOY1AbRPLAePk4uMcxuJoJEKE2o5Blbi1U_xMmfxWLLFyLC3R0aBYa8ZkTlMiBiGHi6z7JL9mc07X-7B0cH7L-8O65JZoXY4Qle19o2Kzoa-Sdx6kUzsJI8hSPR2ZGMlnntnmySUTESX45O0FMHJfdf13nl5H3bGaYwPgXEdfRuEd6KPqgvWcK9jiEZF7S3vbQUvsZOHMjKWQ_7pkO1Q9DGQPoZZHxW8INEfM83G1ZLiQmeDL1zmlFLj9OpKr9aV_ukdbwkMa1Hi4c43EJ1DQefwN3RWsHcBpcsuEPh4yosqTAXP1sWocFqrsWOczkiGkoo16OxV8GBG3roltOGdEo5V0G1hcqup2yXj4mumDm-J_pCbR__j2x7DzTyYuKh5vwc7q59n8Ql6aCv3NA_GX26_O-k
  priority: 102
  providerName: Directory of Open Access Journals
– databaseName: Health & Medical Collection (ProQuest)
  dbid: 7X7
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3di9QwEA96gvgiftvzlAiCPliuSZqm8UVUPA5BH8SDfSv51NWzvbvu-fc7k2a7rsgiFFra6TZkZjK_TSa_IeRZdDZob1nJnNNlDSG1tJa7ktsIcF1aZUzK8v3UHJ_UHxZykSfcxpxWuR4T00DtB4dz5Idc1AqLSXL9-uy8xKpRuLqaS2hcJdcSdRnYs1qoeY4F4IqWkmeyISaaQ_vzO1alAtvAvTsCfpNDUIG7W2Epsff_C3L-nTn5Ryg6ukVuZgxJ30xKv02uhP4Ouf4xr5LfJb8-L8cfdIjULs1ITe_ptDIAUYqmFHIEyjDCoQiEKj-AroOnOWv9FC5TLY-RLnsKfd5TTA97RZHSYQC7oYBzqaEbDmg67X-5R06O3n95d1zm-gqlBT9dldJVdbDGt1VkxvGogxIseC8A84jKCDi31lSR1yIiaY6LwmAeJ3NKtc46cZ_s9UMfHhLKZHCN587yNtTKG82cDD7oOkhnWGsK8gI6ucv-MXbpr4douqyPDvXRTfooyHMUPZvINnZL8rXOOpcZzbGwxunul17OL_3XN96iMcyiyMadbgwXX7vs3J1ioVJe-1hLPLTh0YbYOGubFsbTtiAHa1PadMHGoAvydH4MCscVG9OH4RJlsLRYBZCvIA8my5tbgtvesexYQdSWTW41dftJv_yWCMQbJEFken93sx6RG8lNGC9Ze0D2VheX4TEgsJV9ktzsN7scMoU
  priority: 102
  providerName: ProQuest
– databaseName: Scholars Portal Journals: Open Access
  dbid: M48
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV3ra9RAEF9KC-IXsT6jVVYQ9IPR7CvJCiIqliLUD-JBv4V96umZ6N211P_emc3e1ZNaCoGE7OTBzszOLDv7-xHyODobtLesZM7pUkJILa3lruQ2QrqubGNMqvL9WB9M5IcjdbRFVqyouQMX507tkE9qMp89P_31-zU4_KvMSPLC_viGTaBw3JAjhGxgTN6B0FTjbOww5_tpaJZKq8TCwyspS0jlVUYi-s97IOLA3Y2YlaD9z8tH_y2r_CtO7V8n13KCSd-MFrFLtkJ_g1w5zEvoN8nJp-niOx0itVOzoKb3dFw2gBBGU305ZtEw_KEIxDE_gCEET3NJ-wwuE9HHgk57CgrpKdaOvaSI9zCAUVFIgqmhZwDRdNwcc4tM9t9_fndQZvKF0oITL0vlKhms8W0VmXE86tAIFrwXkBCJygg4t9ZUkUsREVHHRWGwyJO5pmmddeI22e6HPtwllKngas-d5W2QjTeaORV80DIoZ1hrCvIUOrlb6b5L8xJRd1kfHeqjG_VRkCco-nNE4rhYkq901rkMd46sG7OLH3q2fuhS33iLxrAWRajudGOYf-my53cNC1XjtY9S4aENjzbE2llbtzDYtgXZW5nSWRdweD1Sp3JdkEfrZlA4LueYPgzHKIO8Y2DCsiB3Rstb_wnuiUdOsoI0Gza58aubLf30a0IXrxEhkel7l_jufXI1-QrjJWv3yPZyfhweQI62tA-T3_0BOks69w
  priority: 102
  providerName: Scholars Portal
Title Risk of bias and reporting completeness of randomised controlled trials in burn care: protocol for a systematic review
URI https://bmjopen.bmj.com/content/9/12/e033472.full
https://www.ncbi.nlm.nih.gov/pubmed/31857316
https://www.proquest.com/docview/2347575929
https://www.proquest.com/docview/2329730554
https://pubmed.ncbi.nlm.nih.gov/PMC6937119
https://doaj.org/article/71e07d9df45f45f9a2fbef6cbb683058
Volume 9
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwjV1ba9RAFB60hdIX8W60LiMI-mAwc0km41tbWouwRUor61OYK12tibhbf7_nTLJpV7QUlmTZnGTDucw5yZz5PkJeR2eD9pblzDmdS0ipubXc5dxGKNdLq4xJXb7H1dGZ_DQrZ9cWq6_P4DNRvbc_viGRFJgTl9sIIRWMuJuIypIIC76ejq9UoDrRZeLY4YWUORTq5YAz9J_rbJMtXDyM5E2QWkBgLTklDP9_FZ5_909eS0iH98m9oZKku73pH5A7oX1ItqbDXPkj8vtkvvhOu0jt3CyoaT3t5wcgV9HUSI7lMoxzKAIJy3dg8eDp0Lt-AV8To8eCzlsKmm8pNol9oAjs0IH3UKh2qaFXSNC0XwXzmJwdHpzuH-UDy0JuIVqXeekKGazxdRGZcTzqAPoI3guofERhBOxra4rIpYgIneOiMNjNyZxStbNOPCEbbdeGZ4SyMrjKc2d5HaTyRjNXBh-0DKUzrDYZeQtKboYoWTTpAURUzWCaBk3T9KbJyBsU_dlDbtwsyVc2a9yAa470Ghc3n_RuPOlW_7GHzjCKIiZ3-gEctRlCvFEsFMprH2WJH214tCFWztqqhlG1zsjOypWuVMDh8siRynVGXo2HweA4b2Pa0F2iDBKMgTfLjDztPW-8k5X_ZkSt-eTara4faefnCUa8QihEpp_fWtMvyHYKHsZzVu-QjeWvy_ASSrKlnZC7aqYmKRwnZHN3fzr9Avu9g-PPJ5P0mgO2H2cMtlNZ_wG6STa3
linkProvider BMJ Publishing Group Ltd
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3bbtNAEB2VVAJeEHcMBRYJBA9Y9e76ioQQhVYpbSNUtVLfzF4hUOxSpyB-im9kxnYSglDES6VIiexxstk5OzP2zswBeOyNdoXVPOTGFGGMLjXUWphQaI_heqIzpdos31E6PIzfHSVHK_BrWgtDaZVTm9gaalsbeka-LmScEZmkKF6dfAuJNYp2V6cUGh0sdtzPH3jL1rzcfov6fSLE1ubBm2HYswqEGtE5CRMTxU4rm0eeKyN84TLJnbUSPb2MlMT3XKvIi1h6ahVjvFSUvchNluVGG4nfewFWY6poHcDqxubo_f7sqQ4GSEWSiL69EZfpuv76mXiwEI1ULSTxXwh0Y3h0wRG2fAH_CnL_ztX8w_ltXYUrfdTKXncwuwYrrroOF_f6ffkb8H1_3HxhtWd6rBqmKsu6vQj0i6xNWqfQHG0qiaBztDWiy1nW58kf48eWPaRh44qhlitGCWkvGDWRqBGpDCNrpti86zTrKm5uwuG5zP0tGFR15e4A44kzqRVGi9zFmVUFN4mzrohdYhTPVQDPcJLLfkU2ZXuzI9Oy10dJ-ig7fQTwlERPuvYeyyXFVGel6XuoE5XH8fKLns8u-q_f2CAwzESp_3d7oD79WPbmpMy4izJbWB8n9CqU8Nr51Gid5mjB8wDWplCaT8F8CQXwaHYaFU57RKpy9RnJEJlZhEFmALc75M1GQoX2RHQWQLaAyYWhLp6pxp_aluUptV3kxd3lw3oIl4YHe7vl7vZo5x5cbpcMFyHP12AwOT1z9zH-m-gH_aJj8OG81_lv9r1wvA
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3bbtNAEB2VIlW8IO4YSlkkEDxgxbtre20khAolailUCFEpb2avECh2aVIQv8bXMWM7CUEo4qVSpET2ONnsnLnYOzsH4H6wxpfO8JhbW8YphtTYGGFjYQKm65lRWrdVvgf57mH6apSN1uDXbC8MlVXOfGLrqF1j6Rn5QMhUEZmkKAehL4t4uzN8dvwtJgYpWmmd0Wl0ENn3P3_g7dvk6d4O6vqBEMOX71_sxj3DQGwQqdM4s0nqjXZFEri2IpReSe6dkxj1ZaIlvhdGJ0GkMlDbGBukpkpGbpUqrLESv_ccnFcSsyq0JTVS8-c7mCqVWSb6Rkdc5gPz9TMxYiEuad-QxP8jMKDh0aWQ2DIH_Cvd_btq848wOLwEF_v8lW13gLsMa76-Ahtv-hX6q_D93XjyhTWBmbGeMF071q1KYIRkbfk6JenoXUkEw6RrEGfesb5i_gg_tjwiEzauGeq7ZlSa9oRRO4kGMcswx2aaLfpPs27vzTU4PJOZvw7rdVP7m8B45m3uhDWi8KlyuuQ2886Xqc-s5oWO4BFOctXb5qRqb3tkXvX6qEgfVaePCB6S6HHX6GO1pJjprLJ9N3Ui9ThafdHj-UX_9RvPCQxzUeoE3h5oTj5WvWOpFPeJcqULaUavUotgfMitMXmBvryIYHMGpcUULIwpgnvz06hwWi3StW9OSYZozRJMNyO40SFvPhLack-UZxGoJUwuDXX5TD3-1DYvz6kBIy9vrR7WXdhA665e7x3s34YLrcVwEfNiE9anJ6f-DiaCU7PVWhyDD2dt4r8BtyFzgw
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Risk+of+bias+and+reporting+completeness+of+randomised+controlled+trials+in+burn+care%3A+protocol+for+a+systematic+review&rft.jtitle=BMJ+open&rft.au=Young%2C+Amber&rft.au=Reeves%2C+Barnaby+C&rft.au=Cheng%2C+Hung-Yuan&rft.au=Wasiak%2C+Jason&rft.date=2019-12-18&rft.issn=2044-6055&rft.eissn=2044-6055&rft.volume=9&rft.issue=12&rft.spage=e033472&rft_id=info:doi/10.1136%2Fbmjopen-2019-033472&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2044-6055&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2044-6055&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2044-6055&client=summon