Electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy in multiple myeloma: a feasibility study

• Published in: Journal of hematology and oncology Vol. 7; no. 1; p. 41
• Main Authors: Garcia, M Kay, Cohen, Lorenzo, Guo, Ying, Zhou, Yuhong, You, Bing, Chiang, Joseph, Orlowski, Robert Z, Weber, Donna, Shah, Jatin, Alexanian, Raymond, Thomas, Sheeba, Romaguera, Jorge, Zhang, Liang, Badillo, Maria, Chen, Yiming, Wei, Qi, Lee, Richard, Delasalle, Kay, Green, Vivian, Wang, Michael
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.05.2014; BioMed Central
• Subjects: Acupuncture; Aged; Antineoplastic Combined Chemotherapy Protocols - adverse effects; Antineoplastic Combined Chemotherapy Protocols - therapeutic use; Boronic Acids - administration & dosage; Boronic Acids - adverse effects; Bortezomib; Cancer; Chemotherapy; Electroacupuncture - methods; Feasibility Studies; Female; Gene expression; Genetic aspects; Hematology; Humans; Male; Medical treatment; Medicine; Middle Aged; Multiple Myeloma - drug therapy; Nervous system; Oncology; Oncology, Experimental; Pain; Pain Measurement - methods; Peripheral Nervous System Diseases - chemically induced; Peripheral Nervous System Diseases - therapy; Pyrazines - administration & dosage; Pyrazines - adverse effects; Spinal cord; Thalidomide - administration & dosage; Thalidomide - adverse effects; Time Factors; Treatment Outcome

This single-arm study evaluated feasibility, safety, and initial efficacy of electroacupuncture for thalidomide/bortezomib-induced peripheral neuropathy (PN) in cancer patients with multiple myeloma. Patients with neuropathy ≥ grade 2 received 20 acupuncture treatments over 9 weeks. For the 19 evalu...