Eight week exposure to a high sugar high fat diet results in adiposity gain and alterations in metabolic biomarkers in baboons (Papio hamadryas sp.)

• Published in: Cardiovascular diabetology Vol. 9; no. 1; p. 71
• Main Authors: Higgins, Paul B, Bastarrachea, Raul A, Lopez-Alvarenga, Juan Carlos, Garcia-Forey, Maggie, Proffitt, J Michael, Voruganti, V Saroja, Tejero, M Elizabeth, Mattern, Vicki, Haack, Karin, Shade, Robert E, Cole, Shelley A, Comuzzie, Anthony G
• Format: Journal Article
• Language: English
• Published: England BioMed Central 29.10.2010; BioMed Central Ltd; BMC
• Subjects: Absorptiometry, Photon; Adiponectin - blood; Adiposity; Animals; Behavior; Biomarkers; Biomarkers - blood; Biomedical research; C-Reactive Protein - metabolism; Carbohydrates; Data collection; Design; Diet; Dietary Fats - adverse effects; Dietary Sucrose - adverse effects; Energy Intake; Energy Metabolism; Energy resources; Family medical history; Feeds; Glycated Hemoglobin A - metabolism; Insulin; Insulin - blood; Insulin resistance; Leptin - blood; Male; Metabolic Syndrome - blood; Metabolic Syndrome - etiology; Metabolic Syndrome - physiopathology; Nutrition; Obesity - blood; Obesity - etiology; Obesity - physiopathology; Original Investigation; Papio; Papio hamadryas; Studies; Time Factors; Triglycerides - blood

Baboons (Papio hamadryas Sp.) develop features of the cardiometabolic syndrome and represent a clinically-relevant animal model in which to study the aetiology of the disorder. To further evaluate the baboon as a model for the study of the cardiometabolic syndrome, we developed a high sugar high fat...