Comparison of status epilepticus models induced by pilocarpine and nerve agents - a systematic review of the underlying aetiology and adopted therapeutic approaches

• Published in: Current medicinal chemistry Vol. 18; no. 6; p. 886
• Main Authors: Tang, F R, Loke, W K, Ling, E A
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.02.2011
• Subjects: Animals; Brain - drug effects; Brain - metabolism; Chemical Warfare Agents - pharmacology; Chemical Warfare Agents - toxicity; Humans; Pilocarpine - pharmacology; Pilocarpine - toxicity; Sarin - pharmacology; Sarin - toxicity; Soman - pharmacology; Soman - toxicity; Status Epilepticus - chemically induced; Status Epilepticus - etiology; Status Epilepticus - metabolism; Status Epilepticus - therapy

Among potential radiological, nuclear, biological and chemical weapons, cholinergic nerve agents from chemical weapons remain a realistic terrorist threat due to its combination of high lethality, demonstrated use and relative abundance of un-destroyed stockpiles in various militaries around the wor...