Lobular breast cancer: incidence and genetic and non-genetic risk factors

• Published in: Breast cancer research : BCR Vol. 17; no. 1; p. 37
• Main Authors: Dossus, Laure, Benusiglio, Patrick R
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.03.2015; BioMed Central
• Subjects: Breast cancer; Breast Neoplasms - epidemiology; Breast Neoplasms - etiology; Cancer; Carcinoma, Lobular - epidemiology; Carcinoma, Lobular - etiology; Development and progression; Diagnosis; Disease susceptibility; Environment; Female; Gene mutations; Gene-Environment Interaction; Genetic aspects; Genetic Predisposition to Disease; Genetic research; Genetics; Health aspects; Humans; Incidence; Life Sciences; Mammography; Menopause; Oncology, Experimental; Review; Risk Factors; Santé publique et épidémiologie; Tumor proteins

While most invasive breast cancers consist of carcinomas of the ductal type, about 10% are invasive lobular carcinomas. Invasive lobular and ductal carcinomas differ with respect to risk factors. Invasive lobular carcinoma is more strongly associated with exposure to female hormones, and therefore i...