Prediction of prognostic biomarkers for Interferon-based therapy to Hepatitis C Virus patients: a metaanalysis of the NS5A protein in subtypes 1a, 1b, and 3a

• Published in: Virology journal Vol. 7; no. 1; p. 130
• Main Authors: ElHefnawi, Mahmoud M, Zada, Suher, El-Azab, Iman A
• Format: Journal Article
• Language: English
• Published: BioMed Central Ltd 15.06.2010; BioMed Central; BMC
• Subjects: Analysis; Biological markers; Drug therapy; Hepatitis C virus; Interferon; Markov processes; RNA; United States

Hepatitis C virus (HCV) is a worldwide health problem with no vaccine and the only approved therapy is Interferon-based plus Ribavarin. Response prediction to treatment has health and economic impacts, and is a multi-factorial problem including both host and viral factors (e.g: age, sex, ethnicity,...