Modulating crossover positioning by introducing large structural changes in chromosomes

• Published in: BMC genomics Vol. 16; no. 1; p. 89
• Main Authors: Ederveen, Antoine, Lai, Yuching, van Driel, Marc A, Gerats, Tom, Peters, Janny L
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 15.02.2015; BioMed Central
• Subjects: Analysis; Arabidopsis - genetics; Arabidopsis thaliana; Chromosome Deletion; Chromosome Inversion - radiation effects; Chromosomes; Chromosomes, Plant - chemistry; Chromosomes, Plant - metabolism; Chromosomes, Plant - radiation effects; Crossing Over, Genetic - genetics; Gamma Rays; Gene Frequency; Genetic aspects; Genotype; Loss of Heterozygosity - radiation effects; Meiosis; Physiological aspects; Recombination, Genetic; Germany

Crossing over assures the correct segregation of the homologous chromosomes to both poles of the dividing meiocyte. This exchange of DNA creates new allelic combinations thus increasing the genetic variation present in offspring. Crossovers are not uniformly distributed along chromosomes; rather the...