Constructing a robust protein-protein interaction network by integrating multiple public databases

• Published in: BMC bioinformatics Vol. 12; no. S10; p. S7
• Main Authors: Martha, Venkata-Swamy, Liu, Zhichao, Guo, Li, Su, Zhenqiang, Ye, Yanbin, Fang, Hong, Ding, Don, Tong, Weida, Xu, Xiaowei
• Format: Journal Article
• Language: English
• Published: England BioMed Central 18.10.2011; BioMed Central Ltd; BMC
• Subjects: Algorithms; Bioinformatics; Biology; Cluster analysis; Data mining; Databases, Protein; Disease; Gene expression; Humans; Methods; Models, Biological; Proceedings; Protein Interaction Mapping - methods; Protein Interaction Maps; Proteins; Proteins - chemistry; Proteins - metabolism; Studies; Toxicants

Protein-protein interactions (PPIs) are a critical component for many underlying biological processes. A PPI network can provide insight into the mechanisms of these processes, as well as the relationships among different proteins and toxicants that are potentially involved in the processes. There a...