Antioxidant and anti-inflammatory effects of selenium in oral buccal mucosa and small intestinal mucosa during intestinal ischemia-reperfusion injury

• Published in: Journal of inflammation (London, England) Vol. 11; no. 1; p. 36
• Main Authors: Kim, Yongsoo, Kim, Dong Chil, Cho, Eui-Sic, Ko, Seung-O, Kwon, Woon Yong, Suh, Gil Joon, Shin, Hyo-Keun
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 30.10.2014; BioMed Central
• Subjects: Analysis; Antioxidants; Complications and side effects; Dosage and administration; Drug dosages; Drug therapy; Enzymes; Experiments; Heart attacks; Ischemia; Lipid peroxidation; Lipids; Medical research; Multiple organ dysfunction syndrome; Phosphorylation; Physiological aspects; Reperfusion injury; Rodents; Selenium; Small intestine; Studies; Buccal mucosa; Lipid peroxidation; NF kappaB; Selenium; Ischemia reperfusion injury; Small intestine

The aim of this study were to investigate whether selenium treatment attenuates lipid peroxidation and downregulates the NF-κB pathway in small intestinal mucosa and to examine whether the effect of selenium is also observed in oral buccal mucosa, during small intestinal IR injury. Eighteen rats wer...