Genome-wide association of sleep and circadian phenotypes

• Published in: BMC medical genetics Vol. 8; no. Suppl 1; p. S9
• Main Authors: Gottlieb, Daniel J, O'Connor, George T, Wilk, Jemma B
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 19.09.2007; BioMed Central
• Subjects: Adult; Alleles; Cardiovascular Diseases - genetics; Cardiovascular Diseases - physiopathology; Circadian Rhythm - genetics; Cohort Studies; Female; Gene Frequency; Genetic Linkage; Genome, Human; Genotype; Humans; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Sleep - genetics; Surveys and Questionnaires

Numerous studies suggest genetic influences on sleepiness and circadian rhythms. The Sleep Heart Health Study collected questionnaire data on sleep habits and sleepiness from 2848 Framingham Heart Study Offspring Cohort participants. More than 700 participants were genotyped using the Affymetrix 100...