Obesity associated alterations in the biology of adipose stem cells mediate enhanced tumorigenesis by estrogen dependent pathways - Strong, Amy L; Strong, Thomas A; Rhodes, Lyndsay V; Semon, Julie A; Zhang, Xiujuan; Shi, Zhenzhen; Zhang, Shijia; Gimble, Jeffrey M; Burow, Matthew E; Bunnell, Bruce A (Breast cancer research : BCR, 2013)
Keywords: Adipocytes - metabolism; Adipose tissues; Analysis; Animals; Antibodies; Aromatase - metabolism; Biotechnology industry; Body mass index; Breast cancer; Breast Neoplasms - genetics; Breast Neoplasms - metabolism; Breast Neoplasms - mortality; Breast Neoplasms - pathology; Carcinogenesis; Care and treatment; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Coculture Techniques; Cyclin-Dependent Kinase Inhibitor p16 - genetics; Cyclin-Dependent Kinase Inhibitor p16 - metabolism; Development and progression; Diagnosis; Estrogen Receptor alpha - genetics; Estrogen Receptor alpha - metabolism; Estrogens - metabolism; Estrogens - pharmacology; Female; Gene Expression Profiling; Glutathione S-Transferase pi - genetics; Glutathione S-Transferase pi - metabolism; Health aspects; Humans; Intercellular Signaling Peptides and Proteins - genetics; Intercellular Signaling Peptides and Proteins - metabolism; Leptin; Leptin - genetics; Leptin - metabolism; MCF-7 Cells; Membrane Proteins - genetics; Membrane Proteins - metabolism; Mice; Mortality; Obesity; Obesity - genetics; Obesity - metabolism; Progesterone; Receptors, Estrogen - metabolism; Receptors, Progesterone - metabolism; Risk factors; Signal Transduction; Stem Cells - metabolism; Tumor Burden; United States; Viral antibodies; Women; United States