Development and Standardization of a Furosemide Stress Test to Predict the Severity of Acute Kidney Injury

• Published in: Critical care (London, England) Vol. 17; no. 5; p. R207
• Main Authors: Chawla, Lakhmir S, Davison, Danielle L, Brasha-Mitchell, Ermira, Koyner, Jay L, Arthur, John M, Shaw, Andrew D, Tumlin, James A, Trevino, Sharon A, Kimmel, Paul L, Seneff, Michael G
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 20.09.2013; BioMed Central
• Subjects: Acute Kidney Injury - diagnosis; Acute Kidney Injury - urine; Acute renal failure; Aged; Cohort Studies; Diagnosis; Diuretics; Exercise Test - standards; Exercise Test - trends; Exercise tests; Female; Furosemide; Health aspects; Humans; Male; Middle Aged; Pilot Projects; Predictive Value of Tests; Prognosis; Prospective Studies; Retrospective Studies; Severity of Illness Index

In the setting of early acute kidney injury (AKI), no test has been shown to definitively predict the progression to more severe stages. We investigated the ability of a furosemide stress test (FST) (one-time dose of 1.0 or 1.5 mg/kg depending on prior furosemide-exposure) to predict the development...