Efficacy of a carrageenan nasal spray in patients with common cold: a randomized controlled trial

• Published in: Respiratory research Vol. 14; no. 1; p. 124
• Main Authors: Ludwig, Martin, Enzenhofer, Elisabeth, Schneider, Sven, Rauch, Margit, Bodenteich, Angelika, Neumann, Kurt, Prieschl-Grassauer, Eva, Grassauer, Andreas, Lion, Thomas, Mueller, Christian A
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 13.11.2013; BioMed Central
• Subjects: Administration, Intranasal; Adult; Analysis; Antiviral Agents - administration & dosage; Antiviral Agents - pharmacology; Antiviral Agents - therapeutic use; Carrageenan - administration & dosage; Carrageenan - pharmacology; Carrageenan - therapeutic use; Carrageenin; Clinical trials; Cold (Disease); Colds; Common Cold - drug therapy; Common Cold - virology; Dose-Response Relationship, Drug; Double-Blind Method; Drug therapy; Female; Health aspects; Humans; Intranasal medication; Male; Medical research; Medicine, Experimental; Middle Aged; Nasal Lavage Fluid - virology; Nasal Sprays; Nose; Product development; Rhinovirus - drug effects; Risk factors; Time Factors; Treatment Outcome; Viral infections; Viral Load - drug effects; Virus diseases; United States

The common cold is the most widespread viral infection in humans. Iota-carrageenan has previously shown antiviral effectiveness against cold viruses in clinical trials. This study investigated the efficacy of a carrageenan-containing nasal spray on the duration of the common cold and nasal fluid vir...