Mechanisms underlying Actinobacillus pleuropneumoniae exotoxin ApxI induced expression of IL-1β, IL-8 and TNF-α in porcine alveolar macrophages - Chen, Zeng-Weng; Chien, Maw-Sheng; Chang, Nai-Yun; Chen, Ter-Hsin; Wu, Chi-Ming; Huang, Chienjin; Lee, Wei-Cheng; Hsuan, Shih-Ling (Veterinary research (Paris), 2011)
Keywords: Actinobacillus Infections; Actinobacillus Infections - immunology; Actinobacillus Infections - microbiology; Actinobacillus Infections - veterinary; Actinobacillus pleuropneumoniae; Actinobacillus pleuropneumoniae - physiology; Animals; antiserum; Bacterial Proteins; Bacterial Proteins - metabolism; Blotting, Western; Blotting, Western - veterinary; enzyme-linked immunosorbent assay; gene expression; genes; genetics; heat inactivation; Hemolysin Proteins; Hemolysin Proteins - metabolism; immunology; Integrin beta Chains; Integrin beta Chains - genetics; Integrin beta Chains - metabolism; integrins; interleukin-1beta; Interleukin-1beta - genetics; interleukin-8; Interleukin-8 - genetics; lipopolysaccharides; Lipopolysaccharides - metabolism; lungs; macrophages; Macrophages, Alveolar; Macrophages, Alveolar - metabolism; messenger RNA; metabolism; microbiology; mitogen-activated protein kinase; Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases - genetics; Mitogen-Activated Protein Kinases - metabolism; Mycoplasma; neutralization; physiology; quantitative polymerase chain reaction; Real-Time Polymerase Chain Reaction; Real-Time Polymerase Chain Reaction - veterinary; secretion; Signal Transduction; Sus scrofa; Swine; Swine Diseases; Swine Diseases - immunology; Swine Diseases - microbiology; Trypan Blue; Trypan Blue - metabolism; tumor necrosis factor-alpha; Tumor Necrosis Factor-alpha - genetics; veterinary