Reducing the incidence of infection after caesarean section: implications of prophylaxis with antibiotics for hospital resources

• Published in: BMJ Vol. 299; no. 6706; pp. 1003 - 1006
• Main Authors: Mugford, M., Kingston, J., Chalmers, I.
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 21.10.1989; British Medical Association; BMJ Publishing Group LTD
• Subjects: Ampicillin - therapeutic use; Antibiotics; Cefoxitin - therapeutic use; Cesarean section; Cesarean Section - adverse effects; Cesarean Section - economics; Cost efficiency; Cost estimates; Cost-Benefit Analysis; Dosage; England; Female; Health care costs; Hospital costs; Hospital Departments - economics; Humans; Infections; Obstetrics and Gynecology Department, Hospital - economics; Postnatal care; Postnatal Care - economics; Pregnancy; Premedication - economics; Retrospective Studies; Risk Factors; Statistics as Topic; Surgical Wound Infection - economics; Surgical Wound Infection - prevention & control; Wound infections; England; British Isles, England

OBJECTIVES--To estimate the cost effectiveness of giving prophylactic antibiotics routinely to reduce the incidence of wound infection after caesarean section. DESIGN--Estimation of cost effectiveness was based, firstly, on a retrospective overview of 58 controlled trials and, secondly, on evidence...