Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

• Published in: Current neuropharmacology Vol. 14; no. 3; pp. 260 - 271
• Main Authors: Filograna, Roberta, Beltramini, Mariano, Bubacco, Luigi, Bisaglia, Marco
• Format: Journal Article
• Language: English
• Published: United Arab Emirates Bentham Science Publishers Ltd 01.04.2016; Bentham Science Publishers
• Subjects: Animals; Antioxidants - therapeutic use; Antiparkinson Agents - therapeutic use; Disease Models, Animal; Humans; Oxidative Stress - drug effects; Parkinson Disease - drug therapy

Parkinson's disease (PD) is a degenerative neurological syndrome, which is characterized by the preferential death of dopaminergic (DAergic) neurons in the Substantia Nigra. The pathogenesis of this disorder remains poorly understood and PD is still incurable. Current drug treatments are aimed...