Rhabdomyomas and tuberous sclerosis complex: our experience in 33 cases

• Published in: BMC cardiovascular disorders Vol. 14; no. 1; p. 66
• Main Authors: Sciacca, Pietro, Giacchi, Valentina, Mattia, Carmine, Greco, Filippo, Smilari, Pierluigi, Betta, Pasqua, Distefano, Giuseppe
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 09.05.2014; BioMed Central
• Subjects: Age; Analysis; Behavior; Children; Children & youth; Colleges & universities; Diagnosis; DNA Mutational Analysis; Echocardiography, Doppler; Electrocardiography; Gene mutations; Genetic Predisposition to Disease; Genetic Testing - methods; Health aspects; Heart failure; Heart Neoplasms - complications; Heart Neoplasms - diagnosis; Heart Neoplasms - mortality; Humans; Infant; Infant, Newborn; Infants (Newborn); Intellectual disabilities; Language disorders; Medical treatment; Mutation; Nervous system diseases; Patient outcomes; Patients; Pediatrics; People with disabilities; Phenotype; Predictive Value of Tests; Prognosis; Rhabdomyoma - complications; Rhabdomyoma - diagnosis; Rhabdomyoma - mortality; Risk Factors; Skin; Tuberous sclerosis; Tuberous Sclerosis - complications; Tuberous Sclerosis - diagnosis; Tuberous Sclerosis - genetics; Tumor Suppressor Proteins - genetics; Ultrasonography, Prenatal

Rhabdomyomas are the most common type of cardiac tumors in children. Anatomically, they can be considered as hamartomas. They are usually randomly diagnosed antenatally or postnatally sometimes presenting in the neonatal period with haemodynamic compromise or severe arrhythmias although most neonata...