Intensive glycaemic targets in overweight and obese individuals with gestational diabetes mellitus: clinical trial protocol for the iGDM study

• Published in: BMJ open Vol. 14; no. 2; p. e082126
• Main Authors: Scifres, Christina M, Battarbee, Ashley N, Feghali, Maisa N, Pierce, Stephanie, Edwards, Rodney K, Smith, Emily M, Guise, David, Bhamidipalli, Sruthi, Daggy, Joanne, Tuuli, Methodius G
• Format: Journal Article
• Language: English
• Published: England British Medical Journal Publishing Group 29.02.2024; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Protocol
• Subjects: Birth weight; Body mass index; Cesarean section; Clinical medicine; Clinical trials; Consent; Diabetes in pregnancy; Diabetes, Gestational - drug therapy; Female; Fetal Macrosomia; Gestational diabetes; Glucose; Humans; Hypoglycemia; Infant, Newborn; Maternal medicine; Medicine; Multicenter Studies as Topic; Obesity; Obesity - complications; Obstetrics; Obstetrics and Gynaecology; Overweight; Overweight - complications; Pragmatic Clinical Trials as Topic; Preeclampsia; Pregnancy; Randomized controlled trial; Randomized Controlled Trials as Topic; Respiratory distress syndrome; Womens health; United States > US; Obesity; Diabetes in pregnancy; Randomized controlled trial; Maternal medicine

IntroductionThe prevalence of both obesity and gestational diabetes mellitus (GDM) has increased, and each is associated with adverse perinatal outcomes including fetal overgrowth, neonatal morbidity, hypertensive disorders of pregnancy and caesarean delivery. Women with GDM who are also overweight...