Diagnostic and prognostic role of synovial tissue analysis in juvenile idiopathic arthritis: a monocentric study

• Published in: Rheumatic & musculoskeletal diseases open Vol. 9; no. 4; p. e003296
• Main Authors: Costi, Stefania, Armiraglio, Elisabetta, Pregnolato, Francesca, Chighizola, Cecilia Beatrice, Marino, Achille, Randelli, Pietro Simone, Parafioriti, Antonina, Caporali, Roberto
• Format: Journal Article
• Language: English
• Published: England EULAR 14.12.2023; BMJ Publishing Group LTD; BMJ Publishing Group
• Series: Original research
• Subjects: Arthritis; Arthritis, Juvenile; Arthritis, Juvenile - diagnosis; Arthritis, Juvenile - drug therapy; Biological Therapy; Biopsy; Child; Disease; Disease Progression; Fibrin - metabolism; Foreign bodies; Histology; Humans; Orthopedics; Paediatric Rheumatology; Patients; Pediatrics; Prognosis; Remission (Medicine); Rheumatology; Synovial Membrane - metabolism; Synovitis; Synovitis - pathology; Variables; Arthritis, Juvenile; Synovitis; Biological Therapy

ObjectivesThis study investigates the diagnostic role of synovial tissue analysis in children presenting with arthritis and assesses its prognostic significance to predict clinical outcome in juvenile idiopathic arthritis (JIA).MethodsSynovial samples of paediatric patients undergoing synovial biops...