Successful awake proning is associated with improved clinical outcomes in patients with COVID-19: single-centre high-dependency unit experience

• Published in: BMJ open respiratory research Vol. 7; no. 1; p. e000678
• Main Authors: Hallifax, Rob J, Porter, Benedict ML, Elder, Patrick JD, Evans, Sarah B, Turnbull, Chris D, Hynes, Gareth, Lardner, Rachel, Archer, Kirsty, Bettinson, Henry V, Nickol, Annabel H, Flight, William G, Chapman, Stephen J, Hardinge, Maxine, Hoyles, Rachel K, Saunders, Peter, Sykes, Anny, Wrightson, John M, Moore, Alastair, Ho, Ling-Pei, Fraser, Emily, Pavord, Ian D, Talbot, Nicholas P, Bafadhel, Mona, Petousi, Nayia, Rahman, Najib M
• Format: Journal Article
• Language: English
• Published: England British Thoracic Society 01.09.2020; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Aged; Aged, 80 and over; Betacoronavirus; Body mass index; Chronic obstructive pulmonary disease; Continuous positive airway pressure; Continuous Positive Airway Pressure - methods; Coronavirus Infections - mortality; Coronavirus Infections - therapy; COVID-19; Diabetes; Disease Progression; Emergency medical care; Female; Frailty; Humans; Hypertension; Hypoxia; Intensive care; Intubation; Kidney diseases; Lung diseases; Male; Middle Aged; Mortality; Non-Invasive Ventilation; Noninvasive Ventilation - methods; Odds Ratio; Oxygen Inhalation Therapy - methods; Pandemics; Patient Positioning - methods; Patients; Pneumonia, Viral - mortality; Pneumonia, Viral - therapy; Prone Position; Regression analysis; Respiratory failure; respiratory infection; Retrospective Studies; SARS-CoV-2; Severe acute respiratory syndrome coronavirus 2; Treatment Outcome; United Kingdom; Ventilators; viral infection; Wakefulness; United Kingdom; non invasive ventilation; viral infection; respiratory infection

The SARS-CoV-2 can lead to severe illness with COVID-19. Outcomes of patients requiring mechanical ventilation are poor. Awake proning in COVID-19 improves oxygenation, but on data clinical outcomes is limited. This single-centre retrospective study aimed to assess whether successful awake proning o...