Plasmapheresis reverses all side-effects of a cisplatin overdose--a case report and treatment recommendation

• Published in: BMC cancer Vol. 6; no. 1; p. 1
• Main Authors: Hofmann, Guenter, Bauernhofer, Thomas, Krippl, Peter, Lang-Loidolt, Doris, Horn, Sabine, Goessler, Walter, Schippinger, Walter, Ploner, Ferdinand, Stoeger, Herbert, Samonigg, Hellmut
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 04.01.2006; BioMed Central; BMC
• Subjects: Antineoplastic Agents - blood; Antineoplastic Agents - toxicity; Carcinoma, Non-Small-Cell Lung - drug therapy; Case Report; Cisplatin - blood; Cisplatin - toxicity; Female; Hearing Loss - chemically induced; Humans; Liver - enzymology; Lung Neoplasms - drug therapy; Middle Aged; Nausea - chemically induced; Plasmapheresis - methods; Renal Insufficiency - chemically induced; Time Factors; Vomiting - chemically induced

Cisplatin is widely used as an antineoplastic agent since it is effective against a broad spectrum of different tumours. Nevertheless, it has several potential side effects affecting different organ systems and an overdose may lead to life-threatening complications and even death. We report on a 46-...