Neuroimaging findings in newborns with congenital heart disease prior to surgery: an observational study

• Published in: Archives of disease in childhood Vol. 104; no. 11; pp. 1042 - 1048
• Main Authors: Kelly, Christopher J, Arulkumaran, Sophie, Tristão Pereira, Catarina, Cordero-Grande, Lucilio, Hughes, Emer J, Teixeira, Rui Pedro A G, Steinweg, Johannes K, Victor, Suresh, Pushparajah, Kuberan, Hajnal, Joseph V, Simpson, John, Edwards, A David, Rutherford, Mary A, Counsell, Serena J
• Format: Journal Article
• Language: English
• Published: England BMJ Publishing Group Ltd and Royal College of Paediatrics and Child Health 01.11.2019; BMJ Publishing Group LTD; BMJ Publishing Group
• Subjects: Arteries; Balloon treatment; Body Weight; Brain; cardiac surgery; Cardiac Surgical Procedures; cardiology; Cardiovascular disease; Cardiovascular diseases; Cerebellum; Communication Skills; Congenital diseases; Coronary artery disease; Executive Function; Female; Health risk assessment; Heart Defects, Congenital - physiopathology; Heart Defects, Congenital - surgery; Heart diseases; Heart Disorders; Hemorrhage; Humans; imaging; Infant, Newborn; Infants; Injuries; Lesions; Magnetic resonance imaging; Male; Neonates; neonatology; neurodevelopment; Neurodevelopmental disorders; Neurodevelopmental Disorders - diagnostic imaging; Neurodevelopmental Disorders - physiopathology; Neuroimaging; Newborn babies; NMR; Nuclear magnetic resonance; Observational studies; Original; Original article; Pediatrics; Population Distribution; Population Education; Preoperative Care; Prospective Studies; Substantia alba; Surgery; Transposition; United Kingdom - epidemiology; Young Children; United Kingdom; United Kingdom > UK; cardiac surgery; neonatology; neurodevelopment; imaging; cardiology

ObjectivesNeurodevelopmental impairment has become the most important comorbidity in infants with congenital heart disease (CHD). We aimed to (1) investigate the burden of brain lesions in infants with CHD prior to surgery and (2) explore clinical factors associated with injury.Study designProspecti...