Comparison of brush and biopsy sampling methods of the ileal pouch for assessment of mucosa-associated microbiota of human subjects

• Published in: Microbiome Vol. 2; no. 1; p. 5
• Main Authors: Huse, Susan M, Young, Vincent B, Morrison, Hilary G, Antonopoulos, Dionysios A, Kwon, John, Dalal, Sushila, Arrieta, Rose, Hubert, Nathaniel A, Shen, Lici, Vineis, Joseph H, Koval, Jason C, Sogin, Mitchell L, Chang, Eugene B, Raffals, Laura E
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 14.02.2014; BioMed Central
• Subjects: BASIC BIOLOGICAL SCIENCES; cytology brush; microbial sampling; microbiome; microbiome methods Microbiome methods; mucosal biopsy; mucosal brushing; ulcerative colitis

Mucosal biopsy is the most common sampling technique used to assess microbial communities associated with the intestinal mucosa. Biopsies disrupt the epithelium and can be associated with complications such as bleeding. Biopsies sample a limited area of the mucosa, which can lead to potential sampli...