Recent Advances in Peptide Nucleic Acids as Antibacterial Agents

• Published in: Current medicinal chemistry Vol. 28; no. 6; p. 1104
• Main Authors: Chen, Wei, Dong, Bo, Liu, Wenen, Liu, Zhengchun
• Format: Journal Article
• Language: English
• Published: United Arab Emirates 01.01.2021
• Subjects: Anti-Bacterial Agents - pharmacology; Bacteria; Humans; Peptide Nucleic Acids - pharmacology; RNA, Messenger; Peptide nucleic acid (PNA); messenger RNA (mRNA); antibacterial; ribosomal RNA (rRNA); antibiotic-resistant bacteria; antisense

The emergence of antibiotic-resistant bacteria and the slow progress in searching for new antimicrobial agents makes it hard to treat bacterial infections and cause problems for the healthcare system worldwide, including high costs, prolonged hospitalizations, and increased mortality. Therefore, the...